• 1. Aggregation-induced emission based on a fluorinated macrocycle: visualizing spontaneous and ultrafast solid-state molecular motions at room temperature via F?F interactions?
  Mei Zhang,Jingjing Guo,Tingting Liu,Zhanyu He,Majeed Irfan,Zujin Zhao,Zhuo Zeng J. Mater. Chem. C, 2020,8, 14919-14924
• 2. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
• 3. Aggregation of biologically important peptides and proteins: inhibition or acceleration depending on protein and metal ion concentrations
  Benjamin Gabriel Poulson,Kacper Szczepski,Joanna Izabela Lachowicz,Lukasz Jaremko,Abdul-Hamid Emwas,Mariusz Jaremko RSC Adv., 2020,10, 215-227
• 4. An apparatus for determining small amounts of alchohol in sour milk and urine
  Analyst, 1964,89, 272-275
• 5. Alumina coating on 5 V lithium cobalt fluorophosphate cathode material for lithium secondary batteries – synthesis and electrochemical properties?
  S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Phenol ethers
• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers

Comprehensive Overview of 3-Bromo-2-(3'-bromobenzyloxy)phenylboronic acid (CAS No. 849062-27-7)

3-Bromo-2-(3'-bromobenzyloxy)phenylboronic acid (CAS No. 849062-27-7) is a specialized boronic acid derivative widely utilized in organic synthesis, pharmaceutical research, and material science. This compound features a unique molecular structure combining bromine substituents and a boronic acid functional group, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. Its dual reactivity enables the formation of complex biaryl structures, a critical step in developing drug candidates and advanced materials.

The growing demand for boronic acid-based compounds in medicinal chemistry has spotlighted 3-Bromo-2-(3'-bromobenzyloxy)phenylboronic acid as a key building block. Researchers frequently search for "boronic acid applications in drug discovery" or "Suzuki coupling reagents 2024," reflecting its relevance in cutting-edge science. This compound’s stability and compatibility with diverse reaction conditions align with trends favoring sustainable chemistry and high-yield synthetic routes.

From a structural perspective, the bromine atoms at the 3-position of the phenyl ring and the benzyloxy group enhance electrophilic reactivity, facilitating selective modifications. The boronic acid moiety (–B(OH)₂) further allows for palladium-catalyzed transformations, a feature highly sought after in API manufacturing. Recent studies emphasize its role in synthesizing fluorescent probes and polymeric materials, addressing queries like "how to optimize boronic acid reactions" or "new boron-containing polymers."

In the context of green chemistry, 3-Bromo-2-(3'-bromobenzyloxy)phenylboronic acid exemplifies efficiency, as its byproducts are often non-toxic and recyclable. This aligns with industry shifts toward eco-friendly synthesis, a topic dominating forums such as "green alternatives for cross-coupling." Its compatibility with microwave-assisted synthesis also caters to labs prioritizing time-efficient protocols.

Handling and storage recommendations for this compound emphasize inert atmospheres and moisture-free conditions to preserve its reactivity. While not classified as hazardous, proper laboratory safety practices remain essential, echoing searches for "best practices for handling boronic acids." Its shelf stability and commercial availability (e.g., under catalog numbers like 849062-27-7) make it accessible for both academic and industrial projects.

In summary, 3-Bromo-2-(3'-bromobenzyloxy)phenylboronic acid bridges gaps between traditional organic synthesis and modern materials engineering. Its adaptability to high-throughput screening and catalysis research ensures continued relevance, answering trending questions like "what’s next in boron chemistry." As innovation accelerates, this compound will undoubtedly remain a cornerstone in molecular design.

• 849052-23-9(3-Bromo-2-(4'-chlorobenzyloxy)phenylboronic acid)
• 849052-24-0(3-Bromo-2-(3'-methoxybenzyloxy)phenylboronic acid)
• 849062-18-6(3-Bromo-2-(2'-fluorobenzyloxy)-5-methylphenylboronic acid)
• 190661-29-1(2-Benzyloxyphenylboronic acid)
• 849062-23-3(3-Bromo-5-methyl-2-(3'-methoxybenzyloxy)phenylboronic acid)
• 849052-16-0(3-Bromo-2-(3'-bromobenzyloxy)-5-methylphenylboronic acid)
• 849052-18-2(3-Bromo-2-(4'-chlorobenzyloxy)-5-methylphenylboronic acid)
• 848779-86-2(3-Bromo-2-propoxyphenylboronic acid)
• 849052-17-1(3-Bromo-2-(2'-chlorobenzyloxy)-5-methylphenylboronic acid)
• 849052-22-8(3-Bromo-2-(4'-fluorobenzyloxy)phenylboronic acid)