Production Method 1

1003-68-5

1121-86-4

848353-85-5

Reaction Conditions

1.1 Reagents: Potassium carbonate Catalysts: Copper Solvents: Dimethylformamide ;  20 h, 160 - 170 °C

Reference

Synthesis, pharmacophores, and mechanism study of pyridin-2(1H)-one derivatives as regulators of translation initiation factor 3a

Zhu, Weixing; Shen, Jie; Li, Qianbin; Pei, Qi; Chen, Jun; et al, Archiv der Pharmazie (Weinheim, 2013, 346(9), 654-666

Fluorofenidone Raw materials

• 5-methyl-1,2-dihydropyridin-2-one
• 1-Fluoro-3-iodobenzene

Fluorofenidone Preparation Products

• Fluorofenidone (848353-85-5)

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• 5. Aggregation-induced chiral symmetry breaking of a naphthalimide–cyanostilbene dyad?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinones
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Hydropyridines Pyridinones

• 53427-98-8(5-ETHYL-1-PHENYL-1H-PYRIDIN-2-ONE)
• 1020719-62-3(Pirfenidone-d5)
• 929000-78-2(1-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-4-carbonitrile)
• 536747-52-1(1-(4-Amino-3-fluorophenyl)pyridin-2-one)
• 53179-13-8(Pirfenidone)
• 865452-27-3(2(1H)-Pyridinone, 1-(4-amino-3,5-difluorophenyl)-)
• 53427-82-0(2(1H)-PYRIDINONE, 5-METHYL-1-(1-NAPHTHALENYL)-)
• 53427-78-4(2(1H)-PYRIDINONE, 5-METHYL-1-(4-METHYLPHENYL)-)
• 60532-42-5(N-(4-FLUOROPHENYL)PYRIDIN-2(1H)-ONE)
• 914482-29-4(2(1H)-PYRIDINONE, 1-(4-AMINO-3-FLUOROPHENYL)-4-METHYL-)