Production Method 1

611-33-6

847727-21-3

Reaction Conditions

1.1 Reagents: N-Iodosuccinimide Solvents: Acetic acid ;  70 °C; 18 h, 70 °C; 70 °C → rt

Reference

Palladium-catalyzed synthesis of ammonium sulfinates from aryl halides and a sulfur dioxide surrogate. A gas- and reductant-free process

Emmett, Edward J.; Hayter, Barry R.; Willis, Michael C., Angewandte Chemie, 2014, 53(38), 10204-10208

Production Method 2

611-33-6

847727-21-3

Reaction Conditions

1.1 Reagents: N-Iodosuccinimide Solvents: Acetic acid ;  15 min, 70 °C; 16 h, 70 °C

Reference

Engaging sulfinate salts via Ni/photoredox dual catalysis enables facile Csp2-SO2R coupling

Cabrera-Afonso, Maria Jesus; Lu, Zhi-Peng; Kelly, Christopher B.; Lang, Simon B.; Dykstra, Ryan; et al, Chemical Science, 2018, 9(12), 3186-3191

Production Method 3

611-33-6

847727-21-3

Reaction Conditions

1.1 Reagents: tert-Butyl hydroperoxide ,  Iodine Solvents: 1,2-Dichloroethane ;  24 h, 120 °C
1.2 Reagents: Water

Reference

Regioselective, Molecular Iodine-Mediated C3 Iodination of Quinolines

Sun, Kai; Lv, Yunhe; Wang, Junjie; Sun, Jingjing; Liu, Lulu; et al, Organic Letters, 2015, 17(18), 4416-4419

Production Method 4

611-33-6

847727-21-3

Reaction Conditions

1.1 Reagents: N-Iodosuccinimide Solvents: Acetic acid ;  overnight, rt → 80 °C
1.2 Reagents: Sodium sulfite ;  1 h, rt → 80 °C
1.3 Reagents: Sodium hydroxide Solvents: Water ;  pH 10

Reference

Syntheses, Radiolabelings, and in Vitro Evaluations of Fluorinated PET Radioligands of 5-HT6 Serotoninergic Receptors

Colomb, Julie; Becker, Guillaume; Fieux, Sylvain; Zimmer, Luc; Billard, Thierry, Journal of Medicinal Chemistry, 2014, 57(9), 3884-3890

8-Chloro-3-iodoquinoline Raw materials

• 8-Chloroquinoline

8-Chloro-3-iodoquinoline Preparation Products

• 8-Chloro-3-iodoquinoline (847727-21-3)

• 1. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
• 2. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
  Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
• 3. An aquatic host–guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin?
  José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
• 4. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
• 5. An anti-ultrasonic-stripping effect in confined micro/nanoscale cavities and its applications for efficient multiscale metallic patterning?
  Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Chloroquinolines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Haloquinolines Chloroquinolines

• 49713-55-5(Quinoline,4-chloro-8-iodo-)
• 85092-85-9(5-chloro-3-iodo-1H-indole)
• 859958-87-5(5-Chloro-8-iodoquinoline)
• 1167055-57-3(7-chloro-4-iodo-1H-indole)
• 590371-90-7(4-Chloro-3-iodoquinoline)
• 70237-22-8(4,7-dichloro-3-iodoquinoline)
• 1153763-20-2(3-chloro-4-iodoquinoline)
• 111454-67-2(8-Chloro-6-iodoquinoline)
• 77332-90-2(3-Chloro-5-iodopyridine)
• 1262770-19-3(5-chloro-7-iodo-1h-indole)