Production Method 1

121850-39-3

16973-45-8

827-15-6

Reaction Conditions

1.1 Reagents: Tetramethylammonium iodide Solvents: Acetonitrile

Reference

Reactions of pentafluorophenylxenon(II) hexafluoroarsenate [C6F5Xe]+ [AsF6]- with halide anions in acetonitrile

Frohn, H. J.; et al, Journal of Fluorine Chemistry, 1995, 70(2), 147-54

Production Method 2

51-92-3

827-15-6

Reaction Conditions

1.1 Reagents: Iodine cyanide Solvents: Diglyme

Reference

Preparation, NMR spectra and reactivity of pentafluorophenyltetrafluorosilicates M+ [C6F5SiF4]-

Frohn, H. J.; et al, Journal of Organometallic Chemistry, 1995, 501(1-2), 155-9

Production Method 3

121850-39-3

124302-50-7

827-15-6

Reaction Conditions

1.1 Reagents: Iodide Solvents: Acetonitrile

Reference

The pentafluorophenylxenon(II) cation: [C6F5Xe]+; the first stable system with a xenon-carbon bond

Frohn, Hermann J.; et al, Journal of the Chemical Society, 1989, (10), 625-7

Production Method 4

827-15-6

Reaction Conditions

1.1 Reagents: Potassium fluoride

Reference

Aromatic fluoro derivatives. LXXXVI. Direct addition of pentavalent iodine to fluoro-containing benzenes. Generation of pentafluorophenyltrifluoroiodonium cation

Bardin, V. V.; et al, Zhurnal Organicheskoi Khimii, 1980, 16(6), 1256-63

Production Method 5

1109-15-5

827-15-6

Reaction Conditions

1.1 Reagents: Dichloromethane ,  Xenon difluoride
2.1 Reagents: Iodide Solvents: Acetonitrile

Reference

The pentafluorophenylxenon(II) cation: [C6F5Xe]+; the first stable system with a xenon-carbon bond

Frohn, Hermann J.; et al, Journal of the Chemical Society, 1989, (10), 625-7

Production Method 6

827-15-6

Reaction Conditions

1.1 Reagents: Nitronium tetrafluoroborate Solvents: Acetonitrile
2.1 Solvents: Acetonitrile
3.1 Reagents: Iodine cyanide Solvents: Diglyme

Reference

Preparation, NMR spectra and reactivity of pentafluorophenyltetrafluorosilicates M+ [C6F5SiF4]-

Frohn, H. J.; et al, Journal of Organometallic Chemistry, 1995, 501(1-2), 155-9

Production Method 7

363-72-4

827-15-6

Reaction Conditions

1.1 Reagents: Perfluorobutyl iodide ,  Sodium tert-butoxide Solvents: Dimethylformamide ;  3 min, rt
1.2 Reagents: Water ;  rt

Reference

t-BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes

Liu, Xia; et al, Organic & Biomolecular Chemistry, 2018, 16(6), 886-890

Production Method 8

363-72-4

827-15-6

Reaction Conditions

1.1 Reagents: 2167248-94-2 Solvents: Benzene ;  16 h, rt
1.2 Reagents: Iodine ;  1 h, rt
1.3 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Utilising Sodium-Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C-H and C-F Bond Activations

Maddock, Lewis C. H. ; et al, Angewandte Chemie, 2018, 57(1), 187-191

Production Method 9

602-94-8

827-15-6

Reaction Conditions

1.1 Reagents: Iodine ,  Tripotassium phosphate Solvents: Acetonitrile ;  16 h, 100 °C; 100 °C → rt
1.2 Reagents: Fluorobenzene ,  Sodium persulfate Solvents: Chloroform-d ,  Water ;  rt

Reference

Transition-metal-free decarboxylative iodination: New routes for decarboxylative oxidative cross-couplings

Perry, Gregory J. P.; et al, Journal of the American Chemical Society, 2017, 139(33), 11527-11536

Production Method 10

66080-22-6

827-15-6

Reaction Conditions

1.1 Reagents: Iodine

Reference

Organolanthanoids. IV. Some reactions of bis(polyfluorophenyl)ytterbium compounds

Deacon, Glen B.; et al, Australian Journal of Chemistry, 1983, 36(1), 43-53

Production Method 11

392-56-3

827-15-6

Reaction Conditions

1.1 Reagents: Ethylmagnesium bromide Catalysts: Iron(III) acetylacetonate Solvents: Tetrahydrofuran ;  60 min, -30 °C; 30 min, -30 °C
1.2 Reagents: Iodine Solvents: Tetrahydrofuran ;  30 min, -30 °C; overnight, rt
1.3 Reagents: Sodium thiosulfate ,  Ammonium chloride Solvents: Water

Reference

One-Pot Route to X-perfluoroarenes (X = Br, I) Based on FeIII-Assisted C-F Functionalization and Utilization of These Arenes as Building Blocks for Crystal Engineering Involving Halogen Bonding

Rozhkov, Anton V. ; et al, Crystal Growth & Design, 2020, 20(9), 5908-5921

Production Method 12

1206-46-8

827-15-6

Reaction Conditions

1.1 Reagents: Iodine ,  18-Crown-6 Catalysts: Potassium fluoride Solvents: Acetonitrile

Reference

Reaction of trimethyl(pentafluorophenyl)silane with electrophiles in the presence of fluoride ions

Bardin, V. V.; et al, Zhurnal Obshchei Khimii, 1988, 58(4), 812-15

Production Method 13

34422-57-6

827-15-6

Reaction Conditions

1.1 Reagents: Iodine chloride Solvents: Acetonitrile

Reference

Pentavalent perfluoroorganobismuth compounds

Tyrra, W.; et al, Canadian Journal of Chemistry, 1989, 67(11), 1949-51

Production Method 14

373-68-2

5272-26-4

827-15-6

Reaction Conditions

1.1 Solvents: Acetonitrile
2.1 Reagents: Iodine cyanide Solvents: Diglyme

Reference

Preparation, NMR spectra and reactivity of pentafluorophenyltetrafluorosilicates M+ [C6F5SiF4]-

Frohn, H. J.; et al, Journal of Organometallic Chemistry, 1995, 501(1-2), 155-9

Production Method 15

14353-88-9

5270-94-0

827-15-6

Reaction Conditions

1.1 Catalysts: Tris(2,2′-bipyridine)ruthenium(2+) bis(hexafluorophosphate) Solvents: Acetonitrile ;  20 h, 35 °C

Reference

Visible-Light Photoredox Decarboxylation of Perfluoroarene Iodine(III) Trifluoroacetates for C-H Trifluoromethylation of (Hetero)arenes

Yang, Bin; et al, ACS Catalysis, 2018, 8(4), 2839-2843

Production Method 16

827-15-6

363-72-4

Reaction Conditions

1.1 Reagents: Iodine Solvents: Dichloromethane ;  2 h, 20 °C

Reference

Polyfluoroorganoboron-oxygen compounds. 4. Lithium pentafluorophenyltrimethoxyborate, Li[C6F5B(OMe)3], reactions with selected electrophiles and nucleophiles

Adonin, Nicolay Yu.; et al, Zeitschrift fuer Anorganische und Allgemeine Chemie, 2005, 631(13-14), 2638-2646

Production Method 17

827-15-6

434-90-2

Reaction Conditions

1.1 Reagents: Iodine Solvents: Tetrahydrofuran ;  16 h, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Building Square Planar Cobalt(II) Complexes via Sodium Mediated Cobaltation of Fluoroarenes

Logallo, Alessandra ; et al, Angewandte Chemie, 2022, 61(49),

1,2,3,4,5-pentafluoro-6-iodo-benzene Raw materials

• Pentafluorobenzoic acid
• Bis(trifluoroacetoxy)iodopentafluorobenzene
• Xenon(1+), (pentafluorophenyl)-
• 4,6-Dimethoxypyrimidine
• Hexafluorobenzene
• Ytterbium, bis(pentafluorophenyl)-
• Arsenate(1-),hexafluoro-
• Tris(perfluorophenyl)borane
• 1,2,3,4,5-pentafluorobenzene
• Tetramethylammonium fluoride
• Trimethyl(pentafluorophenyl)silane
• Silane, trifluoro(pentafluorophenyl)-
• tetramethylammonium
• Borate(1-), trifluoro(2,3,4,5,6-pentafluorophenyl)-, (T-4)-

1,2,3,4,5-pentafluoro-6-iodo-benzene Preparation Products

• Decafluorobiphenyl (434-90-2)
• 1,2,3,4,5-pentafluoro-6-iodo-benzene (827-15-6)
• 1,2,3,4,5-pentafluorobenzene (363-72-4)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Iodobenzenes
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

• 2265-93-2(2,4-difluoro-1-iodobenzene)
• 84322-56-5(1,3,5-Trifluoro-2,4,6-triiodobenzene)
• 147808-02-4(1,4-Diiodo-2-fluorobenzene)
• 2265-92-1(2,5-Difluoroiodobenzene)
• 2708-97-6(1,2,3,4-Tetrafluoro-5,6-diiodobenzene)
• 41860-63-3(1,3,5-Trifluoro-2-iodobenzene)
• 392-57-4(1,4-Diiodotetrafluorobenzene)
• 5121-89-1(Benzene, 1,2,3,4-tetrafluoro-5-iodo-)
• 13697-89-7(1,3-difluoro-2-iodobenzene)
• 170112-66-0(3,4,5-Trifluoroiodobenzene)