Production Method 1

111938-17-1

79990-25-3

Reaction Conditions

1.1 Solvents: Methanol ;  reflux

Reference

Synthesis, Biological Evaluation, and Computational Analysis of Biaryl Side-Chain Analogs of Solithromycin

Daher, Samer S.; Lee, Miseon; Jin, Xiao; Teijaro, Christiana N.; Wheeler, Steven E.; et al, ChemMedChem, 2021, 16(21), 3368-3373

Production Method 2

6276-04-6

79990-25-3

Reaction Conditions

1.1 Reagents: Sodium methoxide ;  24 h, reflux; reflux → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  rt

Reference

Efficient Discovery of Potent Anti-HIV Agents Targeting the Tyr181Cys Variant of HIV Reverse Transcriptase

Jorgensen, William L.; Bollini, Mariela; Thakur, Vinay V.; Domaoal, Robert A.; Spasov, Krasimir A.; et al, Journal of the American Chemical Society, 2011, 133(39), 15686-15696

Production Method 3

586-10-7

79990-25-3

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrochloric acid Solvents: Water ;  0 °C; 0 °C; 15 min, 0 °C
1.2 Reagents: Potassium iodide Solvents: Water ;  cooled; reflux

Reference

Discovery of Novel and Potent Leukotriene B4 Receptor Antagonists. Part 1

Goodnow, Robert A. Jr.; Hicks, Alexandra; Sidduri, Achyutharao; Kowalczyk, Agnieszka; Dominique, Romyr; et al, Journal of Medicinal Chemistry, 2010, 53(9), 3502-3516

Production Method 4

33844-21-2

79990-25-3

Reaction Conditions

1.1 Reagents: Copper oxide (Cu2O) ,  Sodium iodide ,  Tripotassium phosphate ,  Oxygen ,  Bismuth nitrate Catalysts: Palladium trifluoroacetate Solvents: Dimethyl sulfoxide ;  10 h, 170 °C

Reference

Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group

Fu, Zhengjiang ; Jiang, Yongqing; Wang, Shuiliang; Song, Yuanyuan; Guo, Shengmei ; et al, Organic Letters, 2019, 21(9), 3003-3007

1-iodo-3-methoxy-5-nitrobenzene Raw materials

• 5-Iodobenzene-1,3-diamine
• 4-methoxy-2-nitrobenzoic acid
• 1-Iodo-3,5-dinitrobenzene
• 3-Methoxy-5-nitroaniline

1-iodo-3-methoxy-5-nitrobenzene Preparation Products

• 1-iodo-3-methoxy-5-nitrobenzene (79990-25-3)

• 1. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
• 2. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 3. Exciton manipulation in rippled transition metal dichalcogenides?
  Chen Long,Ying Dai,Jianwei Li,Hao Jin Nanoscale, 2020,12, 21124-21130
• 4. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 5. Excited-state proton-coupled electron transfer within ion pairs?
  Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes Nitrophenyl ethers

• 89487-91-2(2-Iodo-4-nitrophenol)
• 5399-03-1(2-Iodo-4-nitroanisole)
• 31106-75-9(1,3-Diiodo-2-methoxy-5-nitrobenzene)
• 52692-09-8(4-Iodo-2-nitroanisole)
• 920504-08-1(1,2-Diiodo-4-methoxy-5-nitrobenzene)
• 89677-78-1(Benzene,2-iodo-5-methoxy-1,3-dinitro-)
• 58755-70-7(4-Iodo-3-nitroanisole)
• 214279-40-0(2-Iodo-4-methoxy-1-nitrobenzene)
• 5458-84-4(2-Iodo-5-nitroanisole)
• 4072-45-1(Iodonium,(4-methoxyphenyl)(4-nitrophenyl)-, bromide (1:1))