Cas no 79722-21-7 (Tert-Butyl N-(benzyloxy)carbamate)

Tert-Butyl N-(benzyloxy)carbamate structure
79722-21-7 structure
Product Name:Tert-Butyl N-(benzyloxy)carbamate
CAS No:79722-21-7
MF:C12H17NO3
MW:223.268283605576
MDL:MFCD00191873
CID:562990
PubChem ID:87564692
Update Time:2025-07-28

Tert-Butyl N-(benzyloxy)carbamate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl benzyloxycarbamate
    • tert-Butyl N-(Benzyloxy)carbamate
    • Carbamic acid,N-(phenylmethoxy)-, 1,1-dimethylethyl ester
    • tert-butyl N-benzyloxycarbamate
    • tert-butyl N-phenylmethoxycarbamate
    • N-Boc-Bn
    • N-(Benzyloxy)carbamic Acid tert-Butyl Ester
    • N-Boc-O-benzylhydroxylamine
    • tert-Butyl-N-benzyloxycarbamate
    • Carbamic acid, (phenylmethoxy)-, 1,1-dimethylethyl ester
    • (tert-butoxy)-N-(phenylmethoxy)carboxamide
    • tert-butyl(benzyloxy)carbamate
    • t-butyl N-benzyloxycarbamate
    • t-Butyl-N-benzyloxycarbamate
    • tert-Butyl (benzyloxy)carbamate
    • Carbamic acid, (phenylmethoxy)-, 1,1-dimethylethyl ester (9CI)
    • 1,1-Dimethylethyl [(phenylmethyl)oxy]carbamate
    • N-(tert-Butoxycarbonyl)-O-benzylhydroxylamine
    • Tert-Butyl N-(benzyloxy)carbamate
    • MDL： MFCD00191873
    • Inchi： 1S/C12H17NO3/c1-12(2,3)16-11(14)13-15-9-10-7-5-4-6-8-10/h4-8H,9H2,1-3H3,(H,13,14)
    • InChI Key： MZNBNPWFHGWAGH-UHFFFAOYSA-N
    • SMILES： O=C(NOCC1C=CC=CC=1)OC(C)(C)C

Computed Properties

  • Exact Mass: 223.12100
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 5
  • Complexity: 217
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 47.6
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: 2.5

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.078±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 46.0 to 50.0 deg-C
  • Solubility: Very slightly soluble (0.4 g/l) (25 o C),
  • PSA: 47.56000
  • LogP: 3.03380
  • Solubility: Not determined

Tert-Butyl N-(benzyloxy)carbamate Security Information

Tert-Butyl N-(benzyloxy)carbamate Customs Data

  • HS CODE：2924299090
  • Customs Data：

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Tert-Butyl N-(benzyloxy)carbamate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
T137043-1g
Tert-Butyl N-(benzyloxy)carbamate
 79722-21-7 ≥98.0%
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SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
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Tert-Butyl N-(benzyloxy)carbamate
 79722-21-7 ≥98.0%
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SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
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Fluorochem
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Fluorochem
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Chemenu
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Tert-Butyl N-(benzyloxy)carbamate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: 4-Methylmorpholine Solvents: Dichloromethane ;  22 h, rt
Reference
Studies at the ionizable position of cephalosporins and penicillins: hydroxamates as substitutes for the traditional carboxylate group
Majewski, Mark W.; et al, Journal of Antibiotics, 2017, 70(3), 292-296

Production Method 2

Reaction Conditions
1.1 Reagents: Sodium bicarbonate Solvents: 1,4-Dioxane ,  Water ;  overnight, rt
1.2 Reagents: Citric acid Solvents: Water ;  pH 4, rt
Reference
Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid
Bieliauskas, Anton V.; et al, Archiv der Pharmazie (Weinheim, 2016, 349(5), 373-382

Production Method 3

Reaction Conditions
1.1 Solvents: Dichloromethane
Reference
Rational Design, Development, and Stability Assessment of a Macrocyclic Four-Hydroxamate-Bearing Bifunctional Chelating Agent for 89Zr
Seibold, Uwe; et al, ChemMedChem, 2017, 12(18), 1555-1571

Production Method 4

Reaction Conditions
1.1 Reagents: Sodium bicarbonate Solvents: 1,4-Dioxane ,  Water ;  overnight, rt
Reference
Acyloxybenzyl and Alkoxyalkyl Prodrugs of a Fosmidomycin Surrogate as Antimalarial and Antitubercular Agents
Courtens, Charlotte; et al, ACS Medicinal Chemistry Letters, 2018, 9(10), 986-989

Production Method 5

Reaction Conditions
1.1 Reagents: Lithium bis(trimethylsilyl)amide Solvents: Tetrahydrofuran ;  -78 °C
1.2 -78 °C → rt
Reference
Lithium hexamethyldisilazide
Gray, Matthew; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2004, 1, 1-12

Production Method 6

Reaction Conditions
1.1 Reagents: Lithium bis(trimethylsilyl)amide Solvents: Tetrahydrofuran
1.2 -
1.3 Reagents: Water
Reference
Synthesis of O-alkylhydroxylamines by electrophilic amination of alkoxides
Foot, Oliver F.; et al, Chemical Communications (Cambridge), 2000, (11), 975-976

Production Method 7

Reaction Conditions
1.1 Reagents: Sodium bicarbonate Solvents: 1,4-Dioxane ,  Water
Reference
Alkylation of N-benzyloxyureas and carbamates
Sulsky, Richard; et al, Tetrahedron Letters, 1989, 30(1), 31-4

Production Method 8

Reaction Conditions
Reference
Product class 5: hydroxylamines
Geffken, D.; et al, Science of Synthesis, 2009, 40, 937-1082

Production Method 9

Reaction Conditions
1.1 Reagents: N-Hydroxyphthalimide ,  Potassium carbonate Solvents: Dimethyl sulfoxide
1.2 Reagents: Hydrazine Solvents: Ethanol ;  reflux
2.1 Solvents: Water
Reference
Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles
Barrios, Francis J.; et al, Synthesis, 2015, 47(2), 175-180

Production Method 10

Reaction Conditions
1.1 Reagents: Hydrazine
2.1 -
Reference
Fluorescent Hydroxylamine Derived from the Fragmentation of PAMAM Dendrimers for Intracellular Hypochlorite Recognition
Wu, Te-Haw; et al, Chemistry - A European Journal, 2013, 19(35), 11672-11675

Production Method 11

Reaction Conditions
1.1 Reagents: Potassium carbonate
2.1 Reagents: Hydrazine
3.1 -
Reference
Fluorescent Hydroxylamine Derived from the Fragmentation of PAMAM Dendrimers for Intracellular Hypochlorite Recognition
Wu, Te-Haw; et al, Chemistry - A European Journal, 2013, 19(35), 11672-11675

Production Method 12

Reaction Conditions
1.1 Reagents: Potassium carbonate
2.1 Reagents: Hydrazine
3.1 -
Reference
Fluorescent Hydroxylamine Derived from the Fragmentation of PAMAM Dendrimers for Intracellular Hypochlorite Recognition
Wu, Te-Haw; et al, Chemistry - A European Journal, 2013, 19(35), 11672-11675

Tert-Butyl N-(benzyloxy)carbamate Raw materials

Tert-Butyl N-(benzyloxy)carbamate Preparation Products

Tert-Butyl N-(benzyloxy)carbamate Related Literature

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