Cas no 796090-23-8 (2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid)

2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid is a versatile heterocyclic building block used in pharmaceutical and agrochemical synthesis. Its trifluoromethyl and chloro substituents enhance reactivity, enabling selective derivatization, while the carboxylic acid group facilitates further functionalization. This compound is valued for its stability and utility in constructing complex molecules, particularly in medicinal chemistry and crop protection applications.
2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid structure
796090-23-8 structure
Product Name:2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid
CAS No:796090-23-8
MF:C7H3ClF3NO2
MW:225.552431344986
MDL:MFCD13188811
CID:850438
PubChem ID:11218389
Update Time:2025-06-17

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-6-(trifluoromethyl)isonicotinic acid
    • 2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid
    • 2-Chloro-6-trifluoromethyl-isonicotinic acid
    • 2-CHLORO-6-(TRIFLUOROMETHYL)-4-PYRIDINECARBOXYLIC ACID
    • 4-Pyridinecarboxylic acid, 2-chloro-6-(trifluoromethyl)-
    • AB67172
    • AGN-PC-004LQN
    • AK110480
    • KB-229955
    • OMXMPMNUSMLQQS-UHFFFAOYSA-N
    • 2435AC
    • NE59463
    • CM10669
    • 2-Chloro-6-trifluoromethylisonicotinic acid
    • Z1695906763
    • 2-(Trifluoromethyl)-6-chloropyridine-4-carboxylic acid
    • 4-Pyridinecarbo
    • AKOS016008866
    • F13423
    • Z1269110217
    • SY097629
    • MFCD13188811
    • 796090-23-8
    • CS-0051936
    • AMY34743
    • EN300-114361
    • DTXSID50459100
    • AC-29101
    • SCHEMBL3243480
    • AS-47358
    • 2-Chloro-6-(trifluoromethyl)isonicotinicacid
    • 2-Chloro-6-(trifluoromethyl)-4-pyridinecarboxylic acid (ACI)
    • DB-093735
    • MDL： MFCD13188811
    • Inchi： 1S/C7H3ClF3NO2/c8-5-2-3(6(13)14)1-4(12-5)7(9,10)11/h1-2H,(H,13,14)
    • InChI Key： OMXMPMNUSMLQQS-UHFFFAOYSA-N
    • SMILES： O=C(C1C=C(C(F)(F)F)N=C(Cl)C=1)O

Computed Properties

  • Exact Mass: 224.9804405g/mol
  • Monoisotopic Mass: 224.9804405g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 234
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 50.2
  • XLogP3: 2.3

Experimental Properties

  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 348.7±42.0 °C at 760 mmHg
  • Flash Point: 164.7±27.9 °C
  • Vapor Pressure: 0.0±0.8 mmHg at 25°C

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Security Information

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
CHENG DOU FEI BO YI YAO Technology Co., Ltd.
FB07169-25g
2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid
 796090-23-8 95%
25g
 $1125 2023-09-07
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
C898834-1g
2-Chloro-6-(trifluoromethyl)isonicotinic acid
 796090-23-8 96%
1g
 1,310.40 2021-05-17
Chemenu
CM177548-5g
2-Chloro-6-(trifluoromethyl)isonicotinic acid
 796090-23-8 95%
5g
 $524 2021-08-05
TRC
C596880-50mg
2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic Acid
 796090-23-8
50mg
 $ 50.00 2022-06-06
TRC
C596880-100mg
2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic Acid
 796090-23-8
100mg
 $ 65.00 2022-06-06
TRC
C596880-500mg
2-Chloro-6-(trifluoromethyl)pyridine-4-carboxylic Acid
 796090-23-8
500mg
 $ 185.00 2022-06-06
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
69R1025-1g
2-Chloro-6-trifluoromethyl-isonicotinic acid
 796090-23-8 96%
1g
 1272.06CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
69R1025-5g
2-Chloro-6-trifluoromethyl-isonicotinic acid
 796090-23-8 96%
5g
 5071.29CNY 2021-05-07
Apollo Scientific
PC421158-1g
2-Chloro-6-(trifluoromethyl)isonicotinic acid
 796090-23-8 97%
1g
 ￡66.00 2025-02-21
Chemenu
CM177548-1g
2-Chloro-6-(trifluoromethyl)isonicotinic acid
 796090-23-8 95%+
1g
 $126 2022-06-10

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Butyllithium ,  Butylmagnesium chloride Solvents: Tetrahydrofuran ,  Hexane ;  0 °C; 5 min, 0 °C
1.2 -79 °C
1.3 Reagents: Hydrochloric acid Solvents: Diethyl ether ,  Water
Reference
Three chloro(trifluoromethyl)pyridines as model substrates for regioexhaustive functionalization
Cottet, Fabrice; Schlosser, Manfred, European Journal of Organic Chemistry, 2004, (18), 3793-3798

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Raw materials

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Preparation Products

2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid Related Literature

Related Categories

796090-23-8 (2-chloro-6-(trifluoromethyl)pyridine-4-carboxylic acid) Related Products

Recommended suppliers
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Henan Dongyan Pharmaceutical Co., Ltd
Nantong Boya Environmental Protection Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Nantong Boya Environmental Protection Technology Co., Ltd
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhengzhou Baoyu Pharmaceutical Co., Ltd.