Production Method 1

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  18 h, rt

Reference

An Efficient Method for the Preparation of Styrene Derivatives via Rh(III)-Catalyzed Direct C-H Vinylation

Otley, Kate D.; Ellman, Jonathan A., Organic Letters, 2015, 17(5), 1332-1335

Production Method 2

619-58-9

79606-46-5

Reaction Conditions

1.1 Reagents: 4-(Dimethylamino)pyridine ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride Solvents: Dichloromethane ;  2 h, rt

Reference

Toward a Protecting-Group-Free Halogen-Metal Exchange Reaction: Practical, Chemoselective Metalation of Functionalized Aromatic Halides Using Dianion-type Zincate, tBu4ZnLi2

Uchiyama, Masanobu; Furuyama, Taniyuki; Kobayashi, Minoru; Matsumoto, Yotaro; Tanaka, Kentaro, Journal of the American Chemical Society, 2006, 128(26), 8404-8405

Production Method 3

5467-74-3

79606-46-5

Reaction Conditions

1.1 Reagents: Chlorosuccinimide ,  Sodium bicarbonate Catalysts: Palladium Solvents: tert-Butyl methyl ether ;  18 h, 80 bar, 45 °C

Reference

Palladium-Catalyzed Aminocarbonylation of N-Chloroamines with Boronic Acids

Li, Wanfang; Wu, Xiao-Feng, Chemistry - A European Journal, 2015, 21(20), 7374-7378

Production Method 4

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C; 12 h, rt
1.2 Reagents: Water ;  rt

Reference

Facile Synthesis of Isoindolinones via Radical-Mediated Intramolecular Coupling of Two C-H Bonds

Han, Shuxiong; He, Shuo; Huang, Zhibin; Zhao, Yingsheng; Chen, Gong, Synlett, 2023, 34(12), 1457-1461

Production Method 5

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C; 12 h, rt

Reference

Remarkably Efficient Iridium Catalysts for Directed C(sp2)-H and C(sp3)-H Borylation of Diverse Classes of Substrates

Hoque, Emdadul Md; Hassan, Mirja Mahamudul Md; Chattopadhyay, Buddhadeb, Journal of the American Chemical Society, 2021, 143(13), 5022-5037

Production Method 6

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C; 12 h, rt

Reference

Amide Effects in C-H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides

Bisht, Ranjana; Hoque, Emdadul Md; Chattopadhyay, Buddhadeb, Angewandte Chemie, 2018, 57(48), 15762-15766

Production Method 7

586-76-5

79606-46-5

Reaction Conditions

1.1 Reagents: 4-(Dimethylamino)pyridine ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride Solvents: Dichloromethane ;  15 h, reflux; reflux → rt

Reference

Development of highly chemoselective bulky zincate complex, tBu4ZnLi2: design, structure, and practical applications in small-/macromolecular synthesis

Furuyama, Taniyuki; Yonehara, Mitsuhiro; Arimoto, Sho; Kobayashi, Minoru; Matsumoto, Yotaro; et al, Chemistry - A European Journal, 2008, 14(33), 10348-10356

Production Method 8

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  30 min, rt

Reference

Versatile Cp*Rh(III)-Catalyzed Selective Ortho-Chlorination of Arenes and Heteroarenes

Lied, Fabian; Lerchen, Andreas; Knecht, Tobias; Mueck-Lichtenfeld, Christian; Glorius, Frank, ACS Catalysis, 2016, 6(11), 7839-7843

Production Method 9

586-75-4

79606-46-5

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C; overnight, rt

Reference

Rhodium-catalyzed direct coupling of benzothioamides with alkenes and alkynes through directed C-H bond cleavage

Yokoyama, Yuki; Unoh, Yuto; Bohmann, Rebekka Anna; Satoh, Tetsuya; Hirano, Koji; et al, Chemistry Letters, 2015, 44(8), 1104-1106

Production Method 10

586-75-4

79606-46-5

Reaction Conditions

1.1 Solvents: Dichloromethane ;  0 °C; overnight, 0 °C → rt

Reference

Organoaluminum-Mediated Direct Cross-Coupling Reactions

Minami, Hiroki; Saito, Tatsuo; Wang, Chao; Uchiyama, Masanobu, Angewandte Chemie, 2015, 54(15), 4665-4668

Production Method 11

586-76-5

79606-46-5

Reaction Conditions

1.1 Reagents: Thionyl chloride Catalysts: Dimethylformamide Solvents: Toluene ;  rt; 0.5 - 1 h, rt
1.2 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C; 0 °C → rt; 0.5 h, rt
1.3 Reagents: Water

Reference

A Practical in situ Generation of the Schwartz Reagent. Reduction of Tertiary Amides to Aldehydes and Hydrozirconation

Zhao, Yigang; Snieckus, Victor, Organic Letters, 2014, 16(2), 390-393

N-Diisopropyl 4-bromobenzamide Raw materials

• 4-Bromobenzoyl chloride
• (4-bromophenyl)boronic acid
• 4-Bromobenzoic acid
• 4-Iodobenzoic acid

N-Diisopropyl 4-bromobenzamide Preparation Products

• N-Diisopropyl 4-bromobenzamide (79606-46-5)

• 1. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
• 2. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 3. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 4. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 5. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Halobenzoic acids and derivatives

• 346708-50-7(Benzamide, 4-bromo-N,N-dipropyl-)
• 35306-75-3(3-Bromo-N-isopropylbenzamide)
• 336182-29-7(N-Isopropyl 4-bromobenzamide)
• 925423-97-8(azetidin-1-yl(4-bromophenyl)methanone)
• 52010-31-8(N,N-Diisopropyl-4-bromo-3-methylbenzamide)
• 5543-27-1((4-Bromophenyl)(pyrrolidin-1-yl)methanone)
• 35309-72-9(3-Bromo-N,N-diisopropylbenzamide)
• 398149-44-5(N-(3-Bromobenzyl)-N-methylbenzamide)
• 27891-07-2(Benzamide, 4-bromo-N,N-bis(1-methylpropyl)-)
• 5892-99-9(N,N-Diethyl-4-bromobenzamide)