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3-Bromo-N-isopropylbenzamide (CAS No. 35306-75-3): A Comprehensive Overview

3-Bromo-N-isopropylbenzamide (CAS No. 35306-75-3) is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceutical research. This compound is characterized by its unique structure, which includes a bromine atom and an isopropylamino group attached to a benzamide framework. The combination of these functional groups imparts specific chemical and biological properties that make it a valuable reagent in various scientific investigations.

The chemical formula of 3-Bromo-N-isopropylbenzamide is C₁₀H₁₂BrNO₂, and its molecular weight is 246.11 g/mol. The compound is a white crystalline solid at room temperature and is soluble in common organic solvents such as dichloromethane, ethanol, and dimethyl sulfoxide (DMSO). These solubility properties make it easy to handle and incorporate into various experimental setups.

In the realm of organic synthesis, 3-Bromo-N-isopropylbenzamide serves as an important intermediate for the synthesis of more complex molecules. Its bromine atom can be readily substituted in nucleophilic substitution reactions, allowing for the introduction of a variety of functional groups. This versatility makes it a valuable starting material for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.

Recent research has highlighted the potential of 3-Bromo-N-isopropylbenzamide in the development of novel therapeutic agents. For instance, studies have shown that compounds derived from this benzamide framework exhibit promising anti-inflammatory and analgesic properties. One such study published in the Journal of Medicinal Chemistry demonstrated that derivatives of 3-Bromo-N-isopropylbenzamide were effective in reducing inflammation in animal models of arthritis. The mechanism of action involves the inhibition of pro-inflammatory cytokines and enzymes, making these compounds potential candidates for the treatment of inflammatory diseases.

Beyond its therapeutic applications, 3-Bromo-N-isopropylbenzamide has also been explored for its use in materials science. Researchers have investigated its potential as a building block for the synthesis of functional polymers and materials with unique properties. For example, a study published in the Journal of Polymer Science reported the synthesis of polymeric materials using 3-Bromo-N-isopropylbenzamide-based monomers. These materials exhibited enhanced mechanical strength and thermal stability, making them suitable for various industrial applications.

The safety profile of 3-Bromo-N-isopropylbenzamide is an important consideration for its use in both research and industrial settings. While it is generally considered safe when handled properly, appropriate precautions should be taken to avoid exposure to skin and eyes, as well as inhalation of vapors. It is recommended to use personal protective equipment (PPE) such as gloves, goggles, and lab coats when working with this compound.

In conclusion, 3-Bromo-N-isopropylbenzamide (CAS No. 35306-75-3) is a multifaceted compound with significant potential in various scientific fields. Its unique chemical structure and versatile reactivity make it an invaluable reagent for organic synthesis, drug development, and materials science. Ongoing research continues to uncover new applications and properties of this compound, further solidifying its importance in modern scientific research.

• 223557-19-5(4-Bromo-N-propylbenzamide)
• 35306-74-2(3-Bromo-N-propylbenzamide)
• 336182-29-7(N-Isopropyl 4-bromobenzamide)
• 79606-46-5(N-Diisopropyl 4-bromobenzamide)
• 35309-72-9(3-Bromo-N,N-diisopropylbenzamide)
• 42498-39-5(N-t-Butyl 3-bromobenzamide)
• 35390-07-9(N-Butyl 3-Bromobenzamide)
• 42498-38-4(N-t-Butyl 4-bromobenzamide)
• 26819-10-3(3-Bromo-N-ethylbenzamide)
• 161258-41-9(N-Benzyl 3-bromobenzamide)