• 1. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
• 4. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
• 5. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridines and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives

Introduction to Pyridine, 2,6-bis(bromomethyl)-, hydrobromide (CAS No. 73004-40-7)

Pyridine, 2,6-bis(bromomethyl)-, hydrobromide (CAS No. 73004-40-7) is a versatile compound with significant applications in the fields of organic synthesis, medicinal chemistry, and materials science. This compound is characterized by its unique pyridine ring structure substituted with bromomethyl groups and a hydrobromide salt. The combination of these functional groups imparts distinct chemical properties that make it an essential reagent in various synthetic pathways and biological studies.

The molecular formula of Pyridine, 2,6-bis(bromomethyl)-, hydrobromide is C₈H₁₀Br₃N, and its molecular weight is approximately 351.97 g/mol. The compound is a white to off-white solid at room temperature and is soluble in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). Its melting point ranges from 185 to 188°C, which is an important physical property for handling and storage.

In the realm of organic synthesis, Pyridine, 2,6-bis(bromomethyl)-, hydrobromide serves as a valuable building block for the construction of complex molecules. The bromomethyl groups are highly reactive and can undergo various transformations such as nucleophilic substitution reactions, cross-coupling reactions, and radical reactions. These reactions enable the synthesis of a wide range of functionalized pyridine derivatives that are crucial in pharmaceuticals, agrochemicals, and other advanced materials.

A recent study published in the Journal of Organic Chemistry highlighted the use of Pyridine, 2,6-bis(bromomethyl)-, hydrobromide in the synthesis of novel pyridine-based ligands for metal complexes. These ligands exhibited enhanced catalytic activity in asymmetric hydrogenation reactions, demonstrating the potential of this compound in developing more efficient and selective catalysts for industrial applications.

In the field of medicinal chemistry, Pyridine, 2,6-bis(bromomethyl)-, hydrobromide has been explored for its biological activities. Research has shown that certain derivatives of this compound possess potent anti-inflammatory and anti-cancer properties. For instance, a study published in the Journal of Medicinal Chemistry reported that a series of pyridine derivatives derived from Pyridine, 2,6-bis(bromomethyl)-, hydrobromide exhibited significant inhibition of cancer cell proliferation through the modulation of specific signaling pathways.

The hydrobromide salt form of this compound also plays a crucial role in its biological activity. The presence of the hydrobromide salt can influence the solubility and bioavailability of the compound in biological systems. This property is particularly important in drug design and development, where optimizing solubility and bioavailability is essential for achieving therapeutic efficacy.

In addition to its synthetic and biological applications, Pyridine, 2,6-bis(bromomethyl)-, hydrobromide has found utility in materials science. Recent advancements in polymer chemistry have led to the development of functional polymers using this compound as a monomer or cross-linking agent. These polymers exhibit unique properties such as high thermal stability and mechanical strength, making them suitable for various applications including coatings, adhesives, and electronic materials.

The environmental impact of compounds like Pyridine, 2,6-bis(bromomethyl)-, hydrobromide is an important consideration in their use. Studies have shown that while this compound is generally stable under normal conditions, proper handling and disposal practices should be followed to minimize any potential environmental risks. Researchers are continuously working on developing greener synthetic methods to produce this compound with reduced environmental impact.

In conclusion, Pyridine, 2,6-bis(bromomethyl)-, hydrobromide (CAS No. 73004-40-7) is a multifaceted compound with a wide range of applications in organic synthesis, medicinal chemistry, and materials science. Its unique chemical structure and properties make it an indispensable reagent in various research and industrial settings. Ongoing research continues to uncover new possibilities for its use in developing innovative solutions across multiple disciplines.

• 337508-56-2(1-(Bromomethyl)isoquinoline hydrobromide)
• 7703-74-4(2,6-Bis(bromomethyl)pyridine)
• 64114-29-0(2-(Bromomethyl)-6-methylpyridine hydrobromide)
• 79313-01-2(2-(Bromomethyl)-4,6-dimethylpyridine)
• 55401-97-3(2-(Bromomethyl)pyridine)
• 31106-82-8(2-(bromomethyl)pyridine;hydrobromide)
• 74417-44-0(1-(Bromomethyl)isoquinoline)
• 68470-59-7(2-(Bromomethyl)-6-methylpyridine)
• 91458-11-6(Pyridine,2,4-bis(bromomethyl)-6-methyl-)
• 1032650-53-5(4-bromo-2-(bromomethyl)pyridine)