Cas no 6967-71-1 (1H-Indole-3-methanol,2-methyl-)

1H-Indole-3-methanol,2-methyl- structure
6967-71-1 structure
Product Name:1H-Indole-3-methanol,2-methyl-
CAS No:6967-71-1
MF:C10H11NO
MW:161.200442552567
CID:522809
PubChem ID:249349
Update Time:2025-04-23

1H-Indole-3-methanol,2-methyl- Chemical and Physical Properties

Names and Identifiers

    • 1H-Indole-3-methanol,2-methyl-
    • (2-methyl-1H-indol-3-yl)methanol
    • 1H-Indole-3-methanol,2-methyl
    • 2-methyl-3-hydroxymethylindole
    • 2-methylindole-3-carbinol
    • 3-Hydroxymethyl-2-methylindol
    • 3-hydroxymethyl-2-methylindole
    • DTXSID10290238
    • SCHEMBL3196770
    • AKOS009334079
    • 6967-71-1
    • NSC-67603
    • AM806323
    • NSC67603
    • NCIOpen2_000024
    • MDL: MFCD06202772
    • Inchi: 1S/C10H11NO/c1-7-9(6-12)8-4-2-3-5-10(8)11-7/h2-5,11-12H,6H2,1H3
    • InChI Key: ASXDLUBNSFVSAU-UHFFFAOYSA-N
    • SMILES: OCC1=C(C)NC2C=CC=CC1=2

Computed Properties

  • Exact Mass: 161.08400
  • Monoisotopic Mass: 161.084
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 160
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 36A^2
  • XLogP3: 1.6

Experimental Properties

  • Density: 1.221
  • Melting Point: 205-206 °C
  • Boiling Point: 365.7°C at 760 mmHg
  • Flash Point: 175°C
  • Refractive Index: 1.678
  • PSA: 36.02000
  • LogP: 1.96860

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Additional information on 1H-Indole-3-methanol,2-methyl-

Comprehensive Guide to 1H-Indole-3-methanol,2-methyl- (CAS No. 6967-71-1): Properties, Applications, and Market Insights

1H-Indole-3-methanol,2-methyl- (CAS No. 6967-71-1) is a specialized organic compound belonging to the indole derivatives family. This compound has garnered significant attention in pharmaceutical and biochemical research due to its unique structural properties and potential applications. With the increasing demand for novel bioactive molecules, 2-methyl-1H-indole-3-methanol has emerged as a compound of interest for researchers and industry professionals alike.

The molecular structure of 1H-Indole-3-methanol,2-methyl- features an indole core with a hydroxymethyl group at the 3-position and a methyl substituent at the 2-position. This specific substitution pattern contributes to its distinctive chemical behavior and biological activity. Recent studies have explored its potential as a building block for more complex molecules in medicinal chemistry, particularly in the development of serotonin receptor modulators and tryptophan-derived compounds.

From a synthetic chemistry perspective, 6967-71-1 serves as a valuable intermediate in organic synthesis. Its reactivity allows for various functional group transformations, making it useful for creating diverse molecular architectures. The compound's stability under standard laboratory conditions and its solubility profile in common organic solvents enhance its utility in research settings. Many synthetic chemists are currently investigating 2-methylindole-3-methanol derivatives for their potential in drug discovery programs.

In the context of current research trends, 1H-Indole-3-methanol,2-methyl- has been studied for its potential biological activities. While not classified as a pharmaceutical compound itself, its structural features resemble those of several bioactive molecules that interact with neurological targets. This has led to increased interest from researchers working on neurotransmitter analogs and central nervous system-targeted compounds. The scientific community continues to explore its potential applications in various biochemical pathways.

The market for indole-based compounds like 6967-71-1 has shown steady growth, particularly in the pharmaceutical and biotechnology sectors. As research into neurological disorders and mental health conditions expands, the demand for specialized intermediates such as 2-methyl-1H-indole-3-methanol has increased correspondingly. Suppliers and manufacturers have noted this trend, with several companies now offering this compound in research quantities with high purity grades.

From a safety and handling perspective, 1H-Indole-3-methanol,2-methyl- requires standard laboratory precautions typical of organic compounds. While not classified as hazardous under normal conditions, proper personal protective equipment should be used when handling the material. Researchers frequently search for information about the stability of indole derivatives and storage conditions for 6967-71-1, which should be kept in cool, dry environments away from strong oxidizers.

Analytical characterization of 2-methylindole-3-methanol typically involves techniques such as nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and high-performance liquid chromatography (HPLC). These methods are crucial for verifying the compound's purity and identity, especially when used as a reference standard or synthetic intermediate. The availability of detailed spectral data for CAS 6967-71-1 has facilitated its adoption in various research applications.

In the broader context of green chemistry initiatives, synthetic approaches to 1H-Indole-3-methanol,2-methyl- have evolved to include more environmentally friendly protocols. Recent publications have highlighted catalytic methods and solvent-free conditions for preparing this and related indole methanol derivatives. These developments align with the growing emphasis on sustainable chemical processes in academic and industrial research.

The future outlook for 6967-71-1 appears promising as research into indole chemistry continues to expand. With ongoing investigations into its potential as a scaffold for bioactive molecules and its utility in organic synthesis, 2-methyl-1H-indole-3-methanol maintains its relevance in chemical research. The compound's versatility ensures it will remain an important tool for scientists working across multiple disciplines, from medicinal chemistry to materials science.

For researchers seeking detailed technical information about 1H-Indole-3-methanol,2-methyl-, numerous resources are available including spectral databases, scientific literature, and specialized chemical catalogs. The compound's well-characterized properties and established synthesis protocols make it accessible for various experimental applications. As the scientific community's understanding of indole-based systems deepens, compounds like CAS 6967-71-1 will likely find even broader utility in cutting-edge research.

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