3-alkylindoles
3-Alkylindoles are a class of chemical compounds characterized by the presence of an alkyl group attached to the third carbon atom of an indole ring. Indoles themselves are heterocyclic organic compounds containing a benzene ring fused to a nitrogen-containing heterocycle, which gives them unique structural and functional properties. The introduction of alkyl substituents at the 3-position significantly influences their physicochemical characteristics and reactivity.
These derivatives exhibit a wide range of applications in various fields due to their diverse chemical behavior. In the pharmaceutical industry, 3-alkylindoles are often utilized as precursors or intermediates for synthesizing drugs with potent biological activities. Their aromatic structure endows them with potential pharmacological properties, such as anti-inflammatory and antioxidant effects.
In addition, 3-alkylindoles find applications in the field of natural product chemistry and flavor science. The unique aroma profiles derived from their structural modifications make them valuable components in perfumery and food additives, contributing to distinctive fragrance notes and taste sensations. Furthermore, they are also explored for their potential use in agrochemicals and material sciences.
Overall, 3-alkylindoles represent a versatile class of compounds with promising prospects across multiple industries due to their structural diversity and multifaceted functionalities.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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1H-Indole, 3-(4-pyridinylmethyl)- | 5275-07-0 | C14H12N2 |
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1H-Indole, 6-methoxy-3-(4-piperidinyl)- | 52157-78-5 | C14H18N2O |
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4-(5-Bromo-1H-indol-3-yl)-2-butanone | 552314-85-9 | C12H12BrNO |
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1H-Indole, 7-methoxy-2,3-dimethyl- | 53918-89-1 | C11H13NO |
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1H-Indole, 5-bromo-3-ethyl-2-methyl- | 646038-04-2 | C11H12BrN |
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Ethyl 8-Fluoro-1,3,4,5-Tetrahydro-2h-Pyrido4,3-BIndole-2-Carboxylate | 58038-66-7 | C14H15FN2O2 |
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4-Thiazolecarboxamide,2-[(1S)-1-aminoethyl]-N-[2-(1H-indol-3-yl)ethyl]- | 58887-22-2 | C16H18N4OS |
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4,6-dimethoxy-3-methyl-1H-Indole | 74973-30-1 | C11H13NO2 |
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7-Methyltryptophol | 39232-85-4 | C11H13NO |
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5-Methoxy-3-methyl-1H-indole-2-carbaldehyde | 30464-90-5 | C11H11NO2 |
Related Literature
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
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Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
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Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
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Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
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