Cas no 6636-71-1 (2-(Pyridin-2-ylmethyl)-amino-ethanol)

2-(Pyridin-2-ylmethyl)-amino-ethanol is a versatile organic compound featuring both pyridine and ethanolamine functional groups, making it useful in coordination chemistry and pharmaceutical synthesis. Its structure allows for chelation with metal ions, rendering it valuable in catalytic applications and material science. The compound’s dual functionality also enables its use as a building block for heterocyclic derivatives or as a ligand in asymmetric synthesis. High purity grades ensure consistent performance in research and industrial processes. Its stability and solubility in common organic solvents further enhance its practicality in synthetic workflows. This compound is particularly relevant in developing bioactive molecules and advanced materials.
2-(Pyridin-2-ylmethyl)-amino-ethanol structure
6636-71-1 structure
Product Name:2-(Pyridin-2-ylmethyl)-amino-ethanol
CAS No:6636-71-1
MF:C8H12N2O
MW:152.193681716919
CID:46918
PubChem ID:81135
Update Time:2025-06-14

2-(Pyridin-2-ylmethyl)-amino-ethanol Chemical and Physical Properties

Names and Identifiers

    • 2-((Pyridin-2-ylmethyl)amino)ethanol
    • (2-Hydroxyethyl)(2-pyridylmethyl)amine
    • N-(2-Hydroxyethyl)-2-picolylamine
    • 2-[(Pyridin-2-ylmethyl)-amino]-ethanol
    • 2-[(Pyridin-2-ylmethyl)amino]ethanol
    • 2-(pyridin-2-ylmethylamino)ethanol
    • Ethanol, 2-[(2-pyridylmethyl)amino]-
    • DTXSID8064432
    • NSC18478
    • NSC-18478
    • CS-0364186
    • SCHEMBL440639
    • FT-0657670
    • 6636-71-1
    • 2-((Pyridin-2-ylmethyl)amino)ethan-1-ol
    • 2-{[(pyridin-2-yl)methyl]amino}ethan-1-ol
    • Ethanol, 2-((2-pyridinylmethyl)amino)-
    • A835437
    • VLMNYMSCQPXJDR-UHFFFAOYSA-N
    • N-(2-pyridylmethyl)-2-aminoethanol
    • 2-[(pyridin-2-ylmethyl)amino]ethan-1-ol
    • methyl (2S)-2-amino-3-(3-hydroxy-4-oxo-1-pyridyl)propanoate
    • NSC 18478
    • 2-[(2-Pyridinylmethyl)amino]ethanol, AldrichCPR
    • 2-[(2-Pyridinylmethyl)amino]ethanol
    • AM101110
    • 3H4NDW53LD
    • AKOS000257969
    • Ethanol, 2-((2-pyridylmethyl)amino)-
    • Ethanol, 2-[(2-pyridinylmethyl)amino]-
    • pyridine, 2-(2-hydroxyethylamino)methyl-
    • 2-(Pyridin-2-ylmethyl)-amino-ethanol
    • MDL: MFCD04035519
    • Inchi: 1S/C8H12N2O/c11-6-5-9-7-8-3-1-2-4-10-8/h1-4,9,11H,5-7H2
    • InChI Key: VLMNYMSCQPXJDR-UHFFFAOYSA-N
    • SMILES: OCCNCC1C=CC=CN=1

Computed Properties

  • Exact Mass: 152.09500
  • Monoisotopic Mass: 152.095
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 98.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -0.4
  • Topological Polar Surface Area: 45.2A^2

Experimental Properties

  • Density: 1.100
  • Boiling Point: 299 oC
  • Flash Point: 135 oC
  • Refractive Index: 1.543
  • PSA: 45.15000
  • LogP: 0.55440

2-(Pyridin-2-ylmethyl)-amino-ethanol Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

2-(Pyridin-2-ylmethyl)-amino-ethanol Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2-(Pyridin-2-ylmethyl)-amino-ethanol Related Literature

Additional information on 2-(Pyridin-2-ylmethyl)-amino-ethanol

Comprehensive Overview of 2-(Pyridin-2-ylmethyl)-amino-ethanol (CAS No. 6636-71-1): Properties, Applications, and Industry Insights

2-(Pyridin-2-ylmethyl)-amino-ethanol (CAS No. 6636-71-1) is a versatile organic compound with a pyridine-based structure, widely recognized for its role in pharmaceutical intermediates, agrochemical synthesis, and specialty chemical formulations. This compound, often referred to by its systematic name or CAS number, has garnered significant attention due to its unique molecular properties, including a balanced hydrophilic-lipophilic character and reactive amino-alcohol functionality. Researchers and industry professionals frequently search for "6636-71-1 synthesis," "2-(Pyridin-2-ylmethyl)-amino-ethanol applications," and "pyridine derivative uses," reflecting its broad utility across scientific disciplines.

The molecular structure of 2-(Pyridin-2-ylmethyl)-amino-ethanol combines a pyridine ring with an ethanolamine side chain, enabling dual reactivity as both a hydrogen bond donor and acceptor. This feature makes it valuable in catalysis, where queries like "pyridine-ethanolamine catalyst" trend in scientific databases. Recent studies highlight its potential in green chemistry applications, aligning with the global focus on sustainable synthesis methods. The compound's solubility profile—miscible in polar solvents like water and ethanol—also supports its use in formulations where "solubility enhancement strategies" are critical, a hot topic in drug delivery system research.

In pharmaceutical contexts, CAS 6636-71-1 serves as a key intermediate for bioactive molecules, particularly those targeting neurological pathways. Online searches for "pyridine derivatives in CNS drugs" correlate with this application. Its structural similarity to neurotransmitter modulators has spurred interest in medicinal chemistry, though rigorous safety assessments are always recommended. The compound's stability under physiological pH ranges (investigated via "6636-71-1 stability studies") further enhances its appeal for biomedical uses.

Industrial applications of 2-(Pyridin-2-ylmethyl)-amino-ethanol extend to corrosion inhibition, where its nitrogen-rich structure forms protective metal chelates—a subject explored in queries like "pyridine-based corrosion inhibitors." Additionally, its role in polymer modification (search term: "amino-ethanol polymer additives") contributes to materials with improved thermal resistance, addressing industry demands for high-performance composites. Analytical methods for this compound, including HPLC and GC-MS protocols (often searched as "6636-71-1 analysis methods"), ensure quality control in these applications.

Environmental and handling considerations for 6636-71-1 follow standard laboratory safety protocols, with particular attention to its amine functionality. While not classified as high-risk, proper storage conditions (searched as "pyridine-ethanolamine storage guidelines") are essential to maintain stability. The compound's biodegradability profile, a growing concern in chemical manufacturing, has been investigated through "ecological impact of pyridine derivatives" studies, showing moderate environmental persistence under aerobic conditions.

Market trends indicate rising demand for 2-(Pyridin-2-ylmethyl)-amino-ethanol, driven by expanding pharmaceutical R&D in Asia-Pacific regions. Patent analysis (search term: "6636-71-1 patent applications") reveals innovative uses in electronic materials and asymmetric synthesis. As regulatory landscapes evolve, documentation of "pyridine-ethanolamine regulatory status" remains crucial for global compliance. Future research directions may explore its potential in energy storage systems, responding to queries about "nitrogen-containing compounds for batteries."

For synthetic chemists, optimization of 6636-71-1 production routes continues to be refined, with microwave-assisted and flow chemistry approaches gaining traction (searched as "green synthesis of pyridine ethanolamines"). The compound's cost-effectiveness compared to similar heterocyclic amines contributes to its commercial viability. Analytical challenges, such as distinguishing stereoisomers (studied via "chiral separation of 2-(Pyridin-2-ylmethyl)-amino-ethanol"), represent active areas of methodological development.

In conclusion, 2-(Pyridin-2-ylmethyl)-amino-ethanol (CAS No. 6636-71-1) exemplifies the importance of multifunctional pyridine derivatives in modern chemistry. Its diverse applications—from life sciences to industrial processes—are reflected in trending search terms like "multipurpose pyridine compounds" and "specialty chemical innovations." As interdisciplinary research progresses, this compound will likely find new roles in emerging technologies, maintaining its relevance across scientific and industrial communities.

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