• 1. Comparing a mononuclear Zn(ii) complex with hydrogen bond donors with a dinuclear Zn(ii) complex for catalysing phosphate ester cleavage
  Guoqiang Feng,Juan C. Mareque-Rivas,Nicholas H. Williams Chem. Commun. 2006 1845

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives 2-pyridylmethylamines

Introduction to 2-(Bis-(2-pyridyl-methyl)-amino)-ethanol (CAS No. 149860-22-0)

2-(Bis-(2-pyridyl-methyl)-amino)-ethanol, also known by its CAS number 149860-22-0, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound has been extensively studied for its unique structural properties and potential applications in drug design and development.

The molecular structure of 2-(Bis-(2-pyridyl-methyl)-amino)-ethanol consists of a central ethanol backbone with two pyridylmethyl groups attached to the nitrogen atom via an amino linkage. This configuration imparts the molecule with a rigid and planar geometry, which is crucial for its interactions with biological targets such as enzymes and receptors.

Recent studies have highlighted the potential of this compound as a lead molecule in the development of new therapeutic agents. For instance, researchers have explored its ability to act as a ligand for various G-protein coupled receptors (GPCRs), which are key targets in the treatment of conditions such as hypertension, anxiety, and pain management.

In addition to its pharmacological applications, 149860-22-0 has also been investigated for its role in chemical synthesis as an intermediate in the construction of more complex molecules. Its unique reactivity under specific reaction conditions makes it a valuable building block in organic synthesis.

The synthesis of 2-(Bis-(2-pyridyl-methyl)-amino)-ethanol typically involves multi-step processes, including nucleophilic substitution and condensation reactions. Recent advancements in catalytic methods have improved the efficiency and scalability of these reactions, making the compound more accessible for large-scale production.

From an analytical standpoint, this compound has been characterized using a variety of spectroscopic techniques, including nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). These analyses have provided critical insights into its molecular structure and stability under different conditions.

In terms of safety and handling, 149860-22-0 is classified as a non-hazardous chemical under standard laboratory conditions. However, appropriate precautions should always be taken when working with any chemical compound to ensure compliance with safety regulations.

The continued exploration of 2-(Bis-(2-pyridyl-methyl)-amino)-ethanol's properties is expected to yield further insights into its potential applications across diverse fields. As research progresses, this compound may play an increasingly important role in advancing both academic understanding and industrial applications.

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