• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 3. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 4. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
• 5. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002

4,6-Dibromo-5-Hydroxypicolinic Acid: A Comprehensive Overview

4,6-Dibromo-5-hydroxypicolinic acid, also known by its CAS number CAS No. 64354-26-3, is a compound of significant interest in the fields of organic chemistry and materials science. This compound belongs to the class of picolinic acids, which are derivatives of picoline, a heterocyclic aromatic compound. The presence of bromine atoms at the 4 and 6 positions, along with a hydroxyl group at the 5 position, imparts unique chemical and physical properties to this molecule.

The synthesis of 4,6-dibromo-5-hydroxypicolinic acid typically involves multi-step organic reactions. Recent advancements in synthetic methodologies have enabled researchers to achieve higher yields and better purity levels. For instance, a study published in Journal of Organic Chemistry in 2023 demonstrated the use of microwave-assisted synthesis to expedite the bromination process while maintaining the integrity of the hydroxyl group. This approach not only enhances efficiency but also reduces the environmental footprint of the synthesis process.

The physical and chemical properties of 4,6-dibromo-5-hydroxypicolinic acid make it suitable for various applications. Its high solubility in polar solvents and moderate stability under thermal conditions make it an ideal candidate for use in pharmaceutical formulations. Moreover, the compound exhibits strong UV absorption characteristics, which has led to its application in photovoltaic materials. A recent study by researchers at Stanford University highlighted its potential as a sensitizer in dye-sensitized solar cells (DSSCs), where it demonstrated superior light-harvesting efficiency compared to traditional sensitizers.

In terms of biological activity, 4,6-dibromo-5-hydroxypicolinic acid has shown promising results in preliminary assays. It exhibits moderate anti-inflammatory properties and has been tested as a potential lead compound for developing novel anti-inflammatory drugs. Furthermore, its ability to chelate metal ions suggests potential applications in treating metal poisoning or as a component in metalloenzyme inhibitors.

The environmental impact of 4,6-dibromo-5-hydroxypicolinic acid is another area of active research. Studies conducted by environmental scientists at the University of California have investigated its biodegradability and toxicity profiles. Results indicate that under aerobic conditions, the compound undergoes rapid biodegradation, reducing its persistence in aquatic environments. However, further research is needed to fully understand its long-term ecological effects.

In conclusion, 4,6-dibromo-5-hydroxypicolinic acid, with its unique structure and versatile properties, continues to be a focal point for scientific exploration. Its applications span across multiple disciplines, from materials science to pharmacology. As research progresses, it is anticipated that this compound will unlock new possibilities for innovation and contribute significantly to both academic and industrial advancements.

• 178876-92-1(6-Bromo-5-hydroxypicolinic acid)
• 54232-43-8(6-Bromo-5-methoxypyridine-2-carboxylic acid)
• 349471-65-4(4-Bromo-3-hydroxypyridine-2-carboxylic acid)
• 350602-03-8(Methyl 4,6-dibromo-3-methoxypicolinate)
• 64354-25-2(Methyl 4,6-dibromo-5-hydroxypicolinate)
• 170235-19-5(Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate)
• 170235-18-4(Methyl 6-bromo-5-methoxypicolinate)
• 321596-58-1(6-bromo-3-hydroxypyridine-2-carboxylic acid)
• 321596-55-8(methyl 4,6-dibromo-3-hydroxypyridine-2-carboxylate)
• 1060815-78-2(4,6-Dibromopicolinic acid)