Cas no 170235-19-5 (Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate)

Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate is a brominated pyridine derivative featuring both hydroxyl and ester functional groups, making it a versatile intermediate in organic synthesis. Its structural properties enable selective modifications, particularly in pharmaceutical and agrochemical applications. The bromine substituent enhances reactivity for cross-coupling reactions, while the hydroxyl group offers further functionalization potential. The methyl ester moiety provides stability and facilitates downstream transformations. This compound is particularly valuable in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs), where precise control over molecular architecture is critical. High purity and consistent quality ensure reliable performance in research and industrial processes.
Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate structure
170235-19-5 structure
Product Name:Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate
CAS No:170235-19-5
MF:C7H6BrNO3
MW:232.0314412117
MDL:MFCD09878491
CID:1081359
PubChem ID:15281236
Update Time:2025-05-21

Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate Chemical and Physical Properties

Names and Identifiers

    • Methyl 6-bromo-5-hydroxypicolinate
    • methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate
    • methyl 6-bromo-5-hydroxypyridine-2-carboxylate
    • 6-bromo-5-hydroxy-pyridine-2-carboxylic acid methyl ester
    • methyl 2-bromo-3-hydroxy-6-pyridinecarboxylate
    • 2-Pyridinecarboxylic acid, 6-broMo-5-hydroxy-, Methyl ester
    • GAVHSGPZDJCNDR-UHFFFAOYSA-N
    • TRA0045020
    • RP27994
    • FCH1324853
    • AX8206170
    • VGA23519
    • SCHEMBL544568
    • AP-501/43409548
    • DB-064776
    • Methyl6-bromo-5-hydroxypicolinate
    • AS-66876
    • methyl 6-bromo-5-hydroxy-2-pyridine carboxylate
    • 170235-19-5
    • MFCD09878491
    • methyl 2-bromo-3-hydroxy-6-pyridine carboxylate
    • J-522537
    • SY261104
    • CS-B1159
    • methyl 6-bromo-5-hydroxy-2-pyridine-carboxylate
    • A882035
    • AKOS022175339
    • DTXSID00570955
    • A10575
    • Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate
    • MDL: MFCD09878491
    • Inchi: 1S/C7H6BrNO3/c1-12-7(11)4-2-3-5(10)6(8)9-4/h2-3,10H,1H3
    • InChI Key: GAVHSGPZDJCNDR-UHFFFAOYSA-N
    • SMILES: BrC1=C(C=CC(C(=O)OC)=N1)O

Computed Properties

  • Exact Mass: 230.95300
  • Monoisotopic Mass: 230.95311g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 176
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 59.4
  • XLogP3: 1.7

Experimental Properties

  • Density: 1.716
  • Boiling Point: 411°C at 760 mmHg
  • Flash Point: 202.4°C
  • Refractive Index: 1.591
  • PSA: 59.42000
  • LogP: 1.33630

Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate Suppliers

Amadis Chemical Company Limited
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(CAS:170235-19-5)Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate
Order Number:A882035
Stock Status:in Stock
Quantity:1g/250mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 11:05
Price ($):581.0/189.0

Additional information on Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate

Methyl 6-Bromo-5-Hydroxy-2-Pyridinecarboxylate (CAS No. 170235-19-5): A Comprehensive Overview

The compound Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate (CAS No. 170235-19-5) is a significant organic compound with a diverse range of applications in various fields, including pharmaceuticals, agrochemicals, and material sciences. This compound belongs to the class of pyridine derivatives, which are widely studied due to their unique chemical properties and biological activities. The structure of Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate consists of a pyridine ring substituted with a bromine atom at position 6, a hydroxyl group at position 5, and a methyl ester group at position 2. These substituents play a crucial role in determining the compound's reactivity, stability, and potential for use in different industries.

Recent studies have highlighted the importance of Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate in the development of novel drugs targeting various diseases. For instance, researchers have explored its potential as an anti-inflammatory agent due to its ability to inhibit specific enzymes involved in inflammatory pathways. Additionally, the compound has shown promise in anticancer research, where it demonstrates selective cytotoxicity against cancer cells without significantly affecting normal cells. These findings underscore the compound's versatility and its potential to contribute to advancements in medicinal chemistry.

The synthesis of Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate involves a series of well-established organic reactions, including bromination, hydroxylation, and esterification. The choice of reaction conditions and reagents is critical to ensure high yields and purity of the final product. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses of this compound, aligning with the growing demand for sustainable chemical processes.

In terms of physical properties, Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate exhibits a melting point of approximately 180°C and is sparingly soluble in water but readily soluble in organic solvents such as dichloromethane and ethyl acetate. These properties make it suitable for various chemical transformations and purification techniques commonly employed in organic synthesis.

The chemical stability of Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate has been extensively studied under different conditions. It is relatively stable under neutral conditions but can undergo hydrolysis in the presence of strong acids or bases. This behavior is crucial for understanding its behavior during storage and transportation as well as its application in industrial processes.

One of the most exciting developments involving Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate is its use as an intermediate in the synthesis of bioactive molecules. For example, it has been employed as a key building block in the construction of complex heterocyclic compounds with potential pharmacological activities. Its ability to undergo various nucleophilic substitutions and cross-coupling reactions makes it an invaluable tool for medicinal chemists.

Furthermore, recent research has explored the application of Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate in materials science, particularly in the development of advanced materials with tailored electronic properties. Its incorporation into polymer matrices has shown promise for creating materials with enhanced conductivity and stability, opening new avenues for its use in electronic devices.

In conclusion, Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate (CAS No. 170235-19-5) is a versatile compound with significant potential across multiple disciplines. Its unique chemical structure, combined with recent advancements in synthesis and application techniques, positions it as a key player in both academic research and industrial innovation. As ongoing studies continue to uncover new properties and uses for this compound, its importance in the chemical sciences is expected to grow further.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:170235-19-5)Methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate
A882035
Purity:99%/99%
Quantity:1g/250mg
Price ($):581.0/189.0
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