Production Method 1

4578-31-8

6736-77-2

64161-84-8

2140-58-1

2596-55-6

Reaction Conditions

1.1R:R:1H-Imidazole, S:D2O, 1 h, 37°C
1.218 h, 37°C
1.3C:Alkaline phosphatase, S:H2O, 24 h, 30°C, pH 8

Reference

A Simple Synthesis of Sugar Nucleoside Diphosphates by Chemical Coupling in Water

By Tanaka, Hidenori et al, Angewandte Chemie, 2012, 51(46), 11531-11534

a-D-Glucopyranose, cyclic1,2-(hydrogen phosphate) (9CI) Raw materials

• Adenosine 5’-Monophosphate Disodium Salt Hydrate
• Glucose-1-phosphate Dipotassium Salt

a-D-Glucopyranose, cyclic1,2-(hydrogen phosphate) (9CI) Preparation Products

• Adenosine 5'-(trihydrogen diphosphate), P'-α-D-glucopyranosyl ester (2140-58-1)
• a-D-Glucopyranose, cyclic1,2-(hydrogen phosphate) (9CI) (64161-84-8)
• Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with adenosine (2596-55-6)

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