Cas no 64-75-5 (Tetracycline hydrochloride)

Tetracycline hydrochloride is a broad-spectrum antibiotic effective against a wide range of bacteria. Its key advantages include fast-acting bacteriostatic and bactericidal activity, making it suitable for treating various infections, including those resistant to penicillin. Additionally, its salt form enhances solubility and stability in aqueous solutions.
Tetracycline hydrochloride structure
Tetracycline hydrochloride structure
Product Name:Tetracycline hydrochloride
CAS No:64-75-5
MF:C22H25ClN2O8
MW:480.895505666733
MDL:MFCD00078142
CID:33820
PubChem ID:87560362
Update Time:2025-08-22

Tetracycline hydrochloride Chemical and Physical Properties

Names and Identifiers

    • Tetracycline Hydrochloride
    • [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
    • Tetracycline HCl
    • ACHROMYCIN HYDROCHLORIDE
    • Tetracycline (hydrochloride)
    • Tetracycline Hydroch
    • alatet
    • paltet
    • partrex
    • qidtet
    • quatrex
    • sumycin
    • teline
    • tet-cy
    • Tetracycline hydrochloride, 'can be used as secondary standard'
    • u-5965
    • unicin
    • Amresco
    • Tetracyclin HCl
    • Tetracycline HC1
    • Tetrabid
    • Topicycline
    • Sustamycin
    • Telotrex
    • Tetramed
    • Cyclopar
    • Actisite
    • Retet
    • TetraSURE
    • Tetracompren
    • Supramycin
    • Stilciclina
    • Remicyclin
    • Hostacycline
    • Tetralution
    • Quadracycline
    • Mephacyclin
    • Triphacyclin
    • Tetramavan
    • Tetrabakat
    • Tetrakap
    • Tetracaps
    • Tetrosol
    • Ricycline
    • Piracaps
    • Diacycine
    • Artomycin
    • Tefilin
    • Subamycin
    • Tetrablet
    • Tetra-
    • Tetracycline hydrochloride, VETRANAL(TM), analytical standard
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
    • Vetquamycin-324
    • Cancycline-250
    • SCHEMBL34248
    • TETRACYCLINE HYDROCHLORIDE [GREEN BOOK]
    • Ro-Cycline
    • CHEMBL454950
    • TETRACYCLINE HYDROCHLORIDE [EP MONOGRAPH]
    • Q27286287
    • 64-75-5 (HCl)
    • MFCD00078142
    • PD087098
    • Tetracycline hydrochloride [USP:JAN]
    • TETRACYCLINE HYDROCHLORIDE [MI]
    • TETRACYCLINE HYDROCHLORIDE [MART.]
    • TETRACYCLINE HYDROCHLORIDE [USP MONOGRAPH]
    • HMS1921C19
    • Pharmakon1600-01500566
    • Tetra-D
    • Tetracycline hydrochloride [JAN]
    • Tetracycline hydrochloride (JP17/USP)
    • Cefracycline tablets
    • Neocycline b
    • Tetracycline hydrochloride (internal use)
    • 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride,(4S,4aS,5aS,6S,12aS)-
    • Panmycin
    • Bristacycline (TN)
    • Tox21_110355_1
    • Tox21_200516
    • Prestwick_434
    • 2-naftacencarboxamida, 4-(dimetilamino)-1,4,4a, 5,5a, 6,11,12 a-octahidro-3, 6,10,12,12a-pentahidroxi-6-metil-1,11-dioxo-, clorhidrato (1:1), (4s, 4as, 5as, 6s, 12as)-
    • TETRACYCLINE HYDROCHLORIDE [VANDF]
    • UNII-P6R62377KV
    • CAS-64-75-5
    • Bristacycline
    • Neocyclin B
    • BCP9000227
    • Tetracycline hydrochloride, British Pharmacopoeia (BP) Reference Standard
    • (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
    • Chlorowodorku tetracykliny
    • Steclin
    • EINECS 200-593-8
    • D02122
    • Tetracycline hydrochloride, >=95% (European Pharmacopoeia HPLC assay)
    • (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride
    • P6R62377KV
    • Tetracycline hydrochloride, powder, BioReagent, suitable for cell culture
    • Achromycin
    • tetracyclinhydrochlorid-
    • Tetracycline hydrochloride 100 microg/mL in Acetonitrile
    • Dumocyclin
    • DTXCID701321
    • HY-B0474
    • TETRACYCLINE HYDROCHLORIDE [WHO-DD]
    • Tetracycline.HCl
    • NSC 757338
    • NSC-757338
    • Chlorhydrate de tetracycline
    • HELIDAC COMPONENT TETRACYCLINE HYDROCHLORIDE
    • APT T3X COMPONENT TETRACYCLINE TETRACYCLINE
    • DTXSID6021321
    • AI3-50120
    • (4S,4AS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride
    • Tetracycline chloride
    • Tetracyn hydrochloride
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4.alpha.,4a.alpha.,5a.alpha.,6.beta.,12a.alpha.)]-
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-
    • (4S,4AS,5AS,6S,12AR)-4-(DIMETHYLAMINO)-1,6,10,11,12A-PENTAHYDROXY-6-METHYL-3,12-DIOXO-3,4,4A,5,5A,6,12,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE HYDROCHLORIDE
    • Sentry av ornacycline
    • CCG-39267
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-
    • Vetquamycin 324
    • TETRACYCLINE HYDROCHLORIDE [USP-RS]
    • D92606
    • Tetraciclina cloridrato [Italian]
    • PharmaVetResiMix 5 Tetracyclines-v10 10 microg/mL in Methanol
    • BCP0726000161
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12alpha))-
    • CCRIS 2351
    • (4S,4aS,5aS,6S,12aS,Z)-2-(amino(hydroxy)methylene)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
    • NCI-c55561;Tetracycline HCl
    • Tox21_110355
    • Tetracyn
    • ALA TET
    • Chlorowodorku tetracykliny [Polish]
    • s2574
    • Tetraciclina cloridrato
    • TETRACYCLINE HYDROCHLORIDE [ORANGE BOOK]
    • Tetracycline hydrochloride, meets USP testing specifications
    • Tetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard
    • (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamidehydrochloride
    • Tetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard
    • SPECTRUM1500566
    • NCGC00180907-01
    • Tetracyclini hydrochloridum
    • NCI-C55561
    • NCGC00258070-01
    • SW196293-4
    • AKOS015951263
    • APT-T3X COMPONENT TETRACYCLINE TETRACYCLINE
    • TETRACYCLINI HYDROCHLORIDUM [WHO-IP LATIN]
    • (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
    • Tetracycline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
    • SR-01000000212
    • Chlorhydrate de tetracycline [French]
    • EC 200-593-8
    • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
    • SR-05000001723-2
    • 2-NAPHTHACENECARBOXAMIDE, 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,6,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-, MONOHYDROCHLORIDE, (4S-(4.ALPHA.,4A.ALPHA.,5A.ALPHA.,6.BETA.,12A.ALPHA.))-
    • NSC757338
    • KS-1431
    • NCGC00180907-02
    • (-)-Tetrahcycline hydrochloride
    • (4S,6S,12aS,4aS,5aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,1 1-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide, chloride
    • 64-75-5
    • TETRACYCLINE HYDROCHLORIDE [WHO-IP]
    • SR-01000000212-4
    • Tetra-wedel
    • Tetracycline hydrochloride, powder
    • TETRACYCLINE HYDROCHLORIDE COMPONENT OF HELIDAC
    • Panmycin hydrochloride
    • TETRACYCLINE TETRACYCLINE COMPONENT OF APT T3X
    • HMS1568K22
    • NCGC00017323-08
    • SR-05000001723
    • NCGC00016291-01
    • T-250 Capsules
    • AMYCIN,HYDROCHLORIDE
    • NS00078913
    • Achromycin V
    • Tetracycline hydrochloride (JP18/USP)
    • SBI-0051530.0002
    • XMEVHPAGJVLHIG-FMZCEJRJSA-N
    • HY-B0474R
    • AT168330
    • Achromycin;Tetracyn
    • Tetracycline hydrochloride - USP
    • Tetracycline (hydrochloride) (Standard)
    • Tetracycline hydrochloride
    • MDL： MFCD00078142
    • Inchi： 1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
    • InChI Key： YCIHPQHVWDULOY-FMZCEJRJSA-N
    • SMILES： Cl.O[C@@]12C(=C(C(N)=O)C([C@H]([C@@H]1C[C@H]1C(=C(C3C(=CC=CC=3[C@@]1(C)O)O)O)C2=O)N(C)C)=O)O

Computed Properties

  • Exact Mass: 480.13000
  • Monoisotopic Mass: 444.153
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 7
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 33
  • Rotatable Bond Count: 2
  • Complexity: 971
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 5
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: _2
  • Topological Polar Surface Area: 182

Experimental Properties

  • Color/Form: Yellow crystals
  • Density: 1.1770
  • Melting Point: 214°C(dec.)(lit.)
  • Boiling Point: 799.4 °C at 760 mmHg
  • Flash Point: 437.3 °C
  • Refractive Index: -253 ° (C=0.5, 0.1mol/L HCl)
  • Solubility: H2O: 10?mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at ?20°C. Stable at 37°C for 4 days.
  • Water Partition Coefficient: 50 g/L
  • Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents.
  • PSA: 181.62000
  • LogP: 1.28790
  • Merck: 9196
  • Sensitiveness: Air & Light Sensitive
  • Specific Rotation: -252 o (c=0.5, H2O)
  • Solubility: It is soluble in water, methanol and ethanol, but insoluble in ether and hydrocarbons.

Tetracycline hydrochloride Security Information

  • Symbol: GHS07
  • Prompt：warning
  • Signal Word：Warning
  • Hazard Statement： H315,H319,H335
  • Warning Statement： P261,P305+P351+P338
  • Hazardous Material transportation number：UN 3077 9 / PGIII
  • WGK Germany：2
  • Hazard Category Code： R36/37/38
  • Safety Instruction： S26-S36
  • FLUKA BRAND F CODES：8-10-23
  • Regulatory Condition Code：Class Q (sugars, alkaloids, antibiotics, hormones)
  • RTECS：QI9100000
  • Hazardous Material Identification： Xi
  • HazardClass：3
  • TSCA：Yes
  • Toxicity：LD50 orally in rats: 6443 mg/kg (Goldenthal)
  • Storage Condition：<0°C
  • Risk Phrases：R36/37/38

Tetracycline hydrochloride Customs Data

  • HS CODE：29413000
  • Customs Data：

    China Customs Code:

    29413000

Tetracycline hydrochloride Pricemore >>

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Tetracycline hydrochloride Production Method

Production Method 1

Reaction Conditions
1.1 Solvents: Ethanol ;  8 h, 180 °C
Reference
Multifunctional Carbon Dots-Based Fluorescence Detection for Sudan I, Sudan IV and Tetracycline Hydrochloride in Foods
Zhang, Min; et al, Nanomaterials, 2022, 12(23),

Tetracycline hydrochloride Raw materials

Tetracycline hydrochloride Preparation Products

Tetracycline hydrochloride Suppliers

Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
(CAS:64-75-5)Tetracycline hydrochloride
Order Number:LE248
Stock Status:in Stock
Quantity:5KG/1KG/25KG/100KG
Purity:99% HPLC
Pricing Information Last Updated:Thursday, 14 August 2025 14:44
Price ($):negotiated
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:64-75-5)Tetracycline hydrochloride
Order Number:LE13129;LE3506
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:08
Price ($):discuss personally

Tetracycline hydrochloride Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Tetracycline hydrochloride Related Literature

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64-75-5 (Tetracycline hydrochloride) Related Products

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Zhengzhou Baoyu Pharmaceutical Co., Ltd.
(CAS:64-75-5)Tetracycline hydrochloride
LE248
Purity:99% HPLC
Quantity:5KG/1KG/25KG/100KG
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:64-75-5)Tetracycline hydrochloride
LE13129;LE3506
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email