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N-Ethylacetamide Chemical and Physical Properties

Names and Identifiers

- N-ethylacetamide
- Ethylacetamide
- Acetamide,N-ethyl
- Acetamidoethane
- Acetoethylamide
- EINECS 210-896-7
- N-Acetylethylamine
- N-Aethylacetamid [German]
- NSC 406307
- Acetamide, N-ethyl-
- N-Aethylacetamid
- N-Ethyl-acetamide
- M9Y95ZE6J9
- PMDCZENCAXMSOU-UHFFFAOYSA-N
- N-ethylethanamide
- WLN: 2MV1
- NSC406307
- KM0629
- 625-50-3
- NS00035066
- MFCD00009029
- N-Ethylacetamide, 99%
- AC2513
- SY016499
- 4-04-00-00347 (Beilstein Handbook Reference)
- AKOS003857793
- A868440
- DTXSID5060803
- C21404
- UNII-M9Y95ZE6J9
- Q27159564
- CHEBI:87370
- ETHYLACETAMIDE, N-
- CS-W011352
- InChI=1/C4H9NO/c1-3-5-4(2)6/h3H2,1-2H3,(H,5,6
- NSC-406307
- BRN 0969292
- AI3-02181
- FT-0632635
- E0324
- NAethylacetamid
- DB-054195
- Acetamide, Nethyl
- DTXCID7043370
- N-Ethylacetamide
- MDL： MFCD00009029
- Inchi： 1S/C4H9NO/c1-3-5-4(2)6/h3H2,1-2H3,(H,5,6)
- InChI Key： PMDCZENCAXMSOU-UHFFFAOYSA-N
- SMILES： O=C(C)NCC
- BRN： 0969292

Computed Properties

Exact Mass: 87.06840
Monoisotopic Mass: 87.068
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Heavy Atom Count: 6
Rotatable Bond Count: 1
Complexity: 51.5
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 2
XLogP3: -0.1
Topological Polar Surface Area: 29.1

Experimental Properties

Color/Form: Colorless transparent liquid
Density: 0.924?g/mL?at 25?°C(lit.)
Melting Point: -32°C(lit.)
Boiling Point: 206°C(lit.)
Flash Point: Fahrenheit: 224.6 ° f
Celsius: 107 ° c
Refractive Index: n20/D 1.433(lit.)
Water Partition Coefficient: Fully misicible in water.
PSA: 29.10000
LogP: 0.53330
FEMA: 3536
Solubility: Soluble in water and alcohol.

N-Ethylacetamide Security Information

Symbol:
Signal Word：Warning
Hazard Statement： H302
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Hazardous Material transportation number：NONH for all modes of transport
WGK Germany：3
Hazard Category Code： 22
Safety Instruction： S23-S24/25
RTECS：AB8500000
Hazardous Material Identification：
TSCA：Yes
Risk Phrases：R23
Safety Term：S24/25
Storage Condition：Store at 4°C,-4At ℃Store…Better

N-Ethylacetamide Customs Data

HS CODE：2924199090
Customs Data：

China Customs Code:
2924199090

Overview:

2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

Declaration elements:

Product Name, component content, use to, packing

Summary:

2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-Ethylacetamide Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
BAI LING WEI Technology Co., Ltd.	954296-25ML	N-Ethylacetamide, 99%	625-50-3	99%	25ML	￥ 634	2021-07-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	E0324-25ml	N-Ethylacetamide	625-50-3	99.0%(GC)	25ml	￥520.0	2022-05-30
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	N14280-25g	N-Ethylacetamide	625-50-3		25g	￥196.0	2021-09-08
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	N14280-5g	N-Ethylacetamide	625-50-3		5g	￥56.0	2021-09-08
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	N14280-100g	N-Ethylacetamide	625-50-3		100g	￥496.0	2021-09-08
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	147400-25G	N-Ethylacetamide	625-50-3		25g	￥1309.88	2023-12-10
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	N834849-100g	N-Ethylacetamide	625-50-3	99%	100g	1,068.00	2021-05-17
abcr	AB135323-25 ml	N-Ethylacetamide, 99%; .	625-50-3	99%	25 ml	€99.10	2023-09-18
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.	E0324-25ML	N-Ethylacetamide	625-50-3	>99.0%(GC)	25ml	￥390.00	2024-04-16
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R013620-1g	N-Ethylacetamide	625-50-3	99%	1g	￥29	2024-05-22

N-Ethylacetamide Production Method

Production Method 1

122-78-1

94832-20-9

625-50-3

88-30-2

Reaction Conditions

1.1 Solvents: Ethanol ; rt; 4 h, rt
1.2 Reagents: Methanesulfonic acid , Sodium cyanoborohydride Solvents: Methanol ; 15 h, pH 3, rt
2.1 Solvents: tert-Butanol , Water ; 18 h, pH 7.4, 65 °C

Reference

Chemoselective Amide Formation Using O-(4-Nitrophenyl)hydroxylamines and Pyruvic Acid Derivatives

Kumar, Sonali; et al, Journal of Organic Chemistry, 2012, 77(23), 10835-10845

Production Method 2

118-83-2

10576-12-2

625-50-3

88-30-2

Reaction Conditions

1.1 Solvents: Dimethylformamide ; rt; rt → 30 °C
1.2 Reagents: Sodium hydroxide ; 30 °C; 1.5 h
2.1 Reagents: Hydrochloric acid Solvents: Water ; 20 min, rt; 2.5 h, rt
2.2 Reagents: Hydrogen ion Solvents: Water ; pH 2, rt
3.1 Solvents: Ethanol ; rt; 4 h, rt
3.2 Reagents: Methanesulfonic acid , Sodium cyanoborohydride Solvents: Methanol ; 15 h, pH 3, rt
4.1 Solvents: tert-Butanol , Water ; 18 h, pH 7.4, 65 °C

Reference

Chemoselective Amide Formation Using O-(4-Nitrophenyl)hydroxylamines and Pyruvic Acid Derivatives

Kumar, Sonali; et al, Journal of Organic Chemistry, 2012, 77(23), 10835-10845

Production Method 3

5459-93-8

625-50-3

91-65-6

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Tris(acetylacetonato)ruthenium , 1,1′-[2-[(Diphenylphosphino)methyl]-2-methyl-1,3-propanediyl]bis[1,1-diphenylpho… , Bis(trifluoromethanesulfonyl)imide Solvents: Tetrahydrofuran , Butyl ether ; 1 bar → 60 bar, rt; 18 h, 60 bar, 160 °C; 60 bar → 1 bar, 160 °C → 0 °C

Reference

: Catalytic N-Alkylation of Amines Using Carboxylic Acids and Molecular Hydrogen

Sorribes, Ivan; et al, Journal of the American Chemical Society, 2015, 137(42), 13580-13587

Production Method 4

127-17-3

625-50-3

88-30-2

Reaction Conditions

1.1 Solvents: tert-Butanol , Water ; 18 h, pH 7.4, 65 °C

Reference

Chemoselective Amide Formation Using O-(4-Nitrophenyl)hydroxylamines and Pyruvic Acid Derivatives

Kumar, Sonali; et al, Journal of Organic Chemistry, 2012, 77(23), 10835-10845

Production Method 5

625-50-3

88-30-2

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Water ; 20 min, rt; 2.5 h, rt
1.2 Reagents: Hydrogen ion Solvents: Water ; pH 2, rt
2.1 Solvents: Ethanol ; rt; 4 h, rt
2.2 Reagents: Methanesulfonic acid , Sodium cyanoborohydride Solvents: Methanol ; 15 h, pH 3, rt
3.1 Solvents: tert-Butanol , Water ; 18 h, pH 7.4, 65 °C

Reference

Chemoselective Amide Formation Using O-(4-Nitrophenyl)hydroxylamines and Pyruvic Acid Derivatives

Kumar, Sonali; et al, Journal of Organic Chemistry, 2012, 77(23), 10835-10845

N-Ethylacetamide Raw materials

N-Ethylacetamide Preparation Products

N-Ethylacetamide Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:625-50-3)N-Ethylacetamide

Order Number:A868440

Stock Status:in Stock

Quantity:500g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 09:11

Price ($):284.0

Email:[email protected]

Product Official Link

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:625-50-3)N-Ethylacetamide, ≥ 99.0%

Order Number:LE14994

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:11

Price ($):discuss personally

Email:[email protected]

N-Ethylacetamide Related Literature

1. Photoreduction of anthraquinone sulphonates in aqueous organic media

H. R. Cooper Trans. Faraday Soc. 1966 62 2865
2. Fractional Stokes–Einstein–Debye relation and orientational entropy effects in strongly hydrogen-bonded liquid amides

Jolanta ?wiergiel,Jan Jad?yn Phys. Chem. Chem. Phys. 2011 13 3911
3. Amino-acids and peptides. Part XIV. Modification of peptides by amino-acid insertion

John S. Davies,Cedric H. Hassall,Keith H. Hopkins J. Chem. Soc. Perkin Trans. 1 1973 2614
4. Iron(ii) carboxylates and simple carboxamides: an inexpensive and modular catalyst system for the synthesis of PLLA and PLLA-PCL block copolymers

Sarah Kirchhecker,Ngoc Nguyen,Stefan Reichert,Karola Lützow,Paul S. Eselem Bungu,Axel Jacobi von Wangelin,Sebastian Sandl,Axel T. Neffe RSC Adv. 2023 13 17102
5. Autoxidation of N-alkyl-amides. Part II. N-alkyl-amide hydroperoxides and di-N-alkyl-amide peroxides

B. F. Sagar J. Chem. Soc. B 1967 428

Related Categories

Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboximidic acids and derivatives Carboximidic acids

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Cas no 625-50-3 (N-Ethylacetamide)

N-Ethylacetamide Chemical and Physical Properties

Names and Identifiers

Computed Properties

Experimental Properties

N-Ethylacetamide Security Information

N-Ethylacetamide Customs Data

China Customs Code:

Overview:

Declaration elements:

Summary:

N-Ethylacetamide Pricemore >>

N-Ethylacetamide Production Method

Production Method 1

Production Method 2

Production Method 3

Production Method 4

Production Method 5

N-Ethylacetamide Raw materials

N-Ethylacetamide Preparation Products

N-Ethylacetamide Suppliers

N-Ethylacetamide Related Literature

Related Categories

625-50-3 (N-Ethylacetamide) Related Products