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• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Anisoles
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides
• Solvents and Organic Chemicals Organic Compounds

1-(3-Methoxyphenyl)ethanamine: An Overview of CAS No. 62409-13-6

1-(3-Methoxyphenyl)ethanamine, also known by its CAS number 62409-13-6, is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique molecular structure, which includes a methoxyphenyl group attached to an ethanamine moiety. The combination of these functional groups endows 1-(3-Methoxyphenyl)ethanamine with distinct chemical properties and biological activities, making it a valuable intermediate in the synthesis of various pharmaceuticals and fine chemicals.

The molecular formula of 1-(3-Methoxyphenyl)ethanamine is C₉H₁₃NO, and its molecular weight is approximately 151.20 g/mol. The compound is a colorless liquid at room temperature and exhibits moderate solubility in water and common organic solvents such as ethanol and acetone. Its physical and chemical properties have been extensively studied, providing a solid foundation for its use in various applications.

In the realm of pharmaceutical research, 1-(3-Methoxyphenyl)ethanamine has garnered significant attention due to its potential as a precursor in the synthesis of drugs targeting specific biological pathways. Recent studies have explored its role in the development of novel therapeutic agents for conditions such as neurodegenerative diseases, pain management, and psychiatric disorders. For instance, researchers at the University of California, San Francisco, have reported that derivatives of 1-(3-Methoxyphenyl)ethanamine exhibit potent neuroprotective effects in animal models of Parkinson's disease, suggesting its potential as a lead compound for further drug development.

Beyond its pharmaceutical applications, 1-(3-Methoxyphenyl)ethanamine has also found utility in the field of materials science. Its ability to form stable complexes with metal ions has led to its use in the synthesis of coordination polymers and metal-organic frameworks (MOFs). These materials have shown promise in applications such as gas storage, catalysis, and drug delivery systems. A study published in the Journal of Materials Chemistry A demonstrated that MOFs derived from 1-(3-Methoxyphenyl)ethanamine exhibit high surface areas and excellent thermal stability, making them suitable for industrial-scale applications.

The synthetic accessibility of 1-(3-Methoxyphenyl)ethanamine further enhances its appeal as a building block for complex molecules. Various synthetic routes have been developed to produce this compound efficiently and cost-effectively. One common method involves the reductive amination of 3-methoxybenzaldehyde with ethylamine using hydrogen gas over a palladium catalyst. This approach yields high purity products with minimal side reactions, making it suitable for large-scale production.

In addition to its synthetic utility, the environmental impact of 1-(3-Methoxyphenyl)ethanamine has been a subject of interest. Studies have shown that it can be synthesized using green chemistry principles, minimizing the use of hazardous reagents and reducing waste generation. This aligns with the growing trend towards sustainable chemical processes and supports the development of eco-friendly products.

The safety profile of 1-(3-Methoxyphenyl)ethanamine has also been extensively evaluated. While it is generally considered safe for use in laboratory settings when proper handling procedures are followed, it is important to note that exposure to high concentrations may cause irritation to the eyes and skin. Therefore, appropriate personal protective equipment (PPE) should be used when handling this compound.

In conclusion, 1-(3-Methoxyphenyl)ethanamine (CAS No. 62409-13-6) is a multifaceted compound with a broad range of applications in pharmaceuticals, materials science, and synthetic chemistry. Its unique chemical structure and favorable properties make it an attractive candidate for further research and development. As ongoing studies continue to uncover new possibilities for this compound, it is likely that its importance will only grow in the coming years.

• 22038-86-4((R)-(+)-1-(4-Methoxyphenyl)ethylamine)
• 574744-39-1((S)-1-(4-Methoxyphenyl)ethanamine hydrochloride)
• 97294-78-5(1-(3,5-dimethoxyphenyl)ethan-1-amine)
• 1167414-89-2((1R)-1-(3-methoxyphenyl)ethan-1-amine hydrochloride)
• 6298-96-0(1-(4-Methoxyphenyl)ethanamine)
• 781580-43-6((1S)-1-(3,5-dimethoxyphenyl)ethan-1-amine)
• 82796-69-8((S)-1-(3-Methoxyphenyl)ethylamine)
• 854184-18-2(1-(3-Methoxyphenyl)ethylamine hydrochloride)
• 88196-70-7((R)-1-(3-Methoxyphenyl)ethanamine)
• 41851-59-6((-)-(S)-1-(4-Methoxyphenyl)ethylamine)