Production Method 1

62016-93-7

4737-41-1

918-84-3

24319-09-3

Reaction Conditions

1.1 Reagents: (Trifluoromethyl)benzene ,  Cesium carbonate ,  N-Chloro-N-(1,1-dimethylethyl)-3,5-bis(trifluoromethyl)benzamide Catalysts: Benzoyl peroxide ;  rt → 65 °C; 7 h, 65 °C; rt → 65 °C; 17 h, 65 °C

Reference

Reagent-dictated site selectivity in intermolecular aliphatic C-H functionalizations using nitrogen-centered radicals

Carestia, Anthony M.; Ravelli, Davide; Alexanian, Erik J., Chemical Science, 2018, 9(24), 5360-5365

Production Method 2

62016-93-7

25346-31-0

4737-41-1

62168-41-6

3814-34-4

918-84-3

24319-09-3

51116-73-5

Reaction Conditions

1.1 Reagents: Bromotrichloromethane ,  2769993-47-5 Solvents: Nitromethane ;  5 min, rt; cooled; 24 h, 28 °C

Reference

Taming the Chlorine Radical: Enforcing Steric Control over Chlorine-Radical-Mediated C-H Activation

Gonzalez, Miguel I. ; Gygi, David; Qin, Yangzhong ; Zhu, Qilei ; Johnson, Elizabeth J. ; et al, Journal of the American Chemical Society, 2022, 144(3), 1464-1472

Production Method 3

62016-93-7

4737-41-1

53521-23-6

918-84-3

53520-46-0

Reaction Conditions

1.1 Reagents: Carbon tetrachloride ,  N-(1,1-Dimethylethyl)-N-[(1-phenylethenyl)oxy]-3,5-bis(trifluoromethyl)benzamide Solvents: (Trifluoromethyl)benzene ;  16 h, rt → 60 °C

Reference

Diversification of aliphatic C-H bonds in small molecules and polyolefins through radical chain transfer

Fazekas, Timothy J. ; Alty, Jill W. ; Neidhart, Eliza K. ; Miller, Austin S. ; Leibfarth, Frank A. ; et al, Science (Washington, 2022, 375(6580), 545-550

Pentane, 1-chloro-3-methyl- Preparation Products

• 3-Bromo-3-methylpentane (25346-31-0)
• 3-(chloromethyl)pentane (4737-41-1)
• Pentane, 2-chloro-3-methyl-, (R*,R*)- (9CI) (53521-23-6)
• 2-bromo-3-methylpentane (62168-41-6)
• 3-(Bromomethyl)pentane (3814-34-4)
• Pentane,3-chloro-3-methyl- (918-84-3)
• 2-chloro-3-methylpentane (24319-09-3)
• Pentane, 2-chloro-3-methyl-, (R*,S*)- (9CI) (53520-46-0)
• Pentane, 1-chloro-3-methyl- (62016-93-7)
• Pentane,1-bromo-3-methyl- (51116-73-5)

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• 2. Emerging enantiomeric resolution materials with homochiral nano-fabrications
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• 4. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
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• 5. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
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