• 1. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 2. An investigation of new infrared nonlinear optical material: BaCdSnSe4, and three new related centrosymmetric compounds: Ba2SnSe4, Mg2GeSe4, and Ba2Ge2S6?
  Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864
• 3. An investigation into the origin of variations in photovoltaic performance using D–D–π–A and D–A–π–A triphenylimidazole dyes with a copper electrolyte?
  Govind Reddy Mol. Syst. Des. Eng., 2021,6, 779-789
• 4. An intramolecular tryptophan-condensation approach for peptide stapling?
  Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
• 5. An apparatus for testing water by measurement of its electrical conductivity
  Analyst, 1912,37, 538-543

Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide (CAS No: 60323-95-7)

Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide is a highly specialized organic compound with the CAS registry number 60323-95-7. This compound belongs to the class of pyridine derivatives, which are widely studied for their unique chemical properties and potential applications in various fields such as pharmaceuticals, agrochemicals, and materials science. The structure of this compound features a pyridine ring with three substituents: a chlorine atom at position 2, a methyl group at position 3, and a nitro group at position 4. Additionally, the presence of an oxide functional group further enhances its reactivity and versatility in chemical reactions.

The synthesis of Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide involves a series of carefully controlled reactions to ensure the precise placement of substituents on the pyridine ring. Recent advancements in synthetic methodologies have enabled chemists to achieve higher yields and better purity levels for this compound. For instance, researchers have explored the use of microwave-assisted synthesis to accelerate reaction times while maintaining product quality. This approach not only improves efficiency but also reduces environmental impact by minimizing solvent usage.

One of the most intriguing aspects of this compound is its reactivity under various conditions. The nitro group at position 4 is particularly reactive and can undergo reduction to form an amino group, which is a valuable transformation in organic synthesis. Similarly, the chlorine atom at position 2 can act as an electrophilic site for nucleophilic substitutions or serve as a leaving group in elimination reactions. The methyl group at position 3 provides steric hindrance, which can influence the regioselectivity of reactions involving this compound.

Recent studies have highlighted the potential of Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide as a precursor for the synthesis of bioactive molecules. For example, researchers have successfully utilized this compound to prepare novel anti-inflammatory agents by incorporating it into heterocyclic frameworks. The ability to modify the substituents on the pyridine ring allows for fine-tuning of pharmacokinetic properties such as solubility and bioavailability.

In addition to its role in drug discovery, this compound has also found applications in agrochemicals. Its derivatives have been shown to exhibit potent insecticidal activity against various pests, making them promising candidates for sustainable pest management solutions. The development of these compounds aligns with current trends toward environmentally friendly agricultural practices.

The oxide functional group present in this compound plays a crucial role in its redox properties. Recent investigations into its electrochemical behavior have revealed its potential as an intermediate in the synthesis of advanced materials such as conductive polymers and metal-organic frameworks (MOFs). These materials hold great promise for applications in energy storage and catalysis.

From a safety standpoint, it is important to note that while Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide is not classified as a hazardous material under standard conditions, proper handling procedures should be followed to ensure workplace safety and environmental protection.

In conclusion, Pyridine, 2-chloro-3-methyl-4-nitro-, 1-oxide (CAS No: 60323-95-7) is a versatile compound with significant potential across multiple disciplines. Its unique structure and reactivity make it an invaluable tool for researchers seeking innovative solutions in pharmaceuticals, agrochemicals, and materials science.

• 60323-96-8(2-chloro-5-methyl-4-nitropyridin-1-ium-1-olate)
• 185017-79-2(Pyridine, 2,5-dichloro-3-methyl-4-nitro-, 1-oxide)
• 1373233-00-1(4-Amino-2-chloro-3-methylpyridin-1-ium-1-olate)
• 2089315-05-7(2,6-Dichloro-3-methyl-4-nitropyridine)
• 79055-56-4(2-chloro-3-methyl-4-nitropyridine)
• 97944-45-1(2-Chloro-5-methyl-4-nitropyridine)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)