Cas no 5874-97-5 (Metaproterenol hemisulfate)

Metaproterenol hemisulfate is a selective β?-adrenergic receptor agonist primarily used as a bronchodilator in the management of reversible airway obstruction, such as asthma and chronic obstructive pulmonary disease (COPD). Its hemisulfate salt form enhances solubility and stability, ensuring consistent pharmacological activity. The compound exhibits rapid onset of action, providing quick relief from bronchospasm, while maintaining a favorable safety profile with minimal cardiovascular side effects compared to non-selective β-agonists. Metaproterenol hemisulfate is compatible with various delivery methods, including oral and inhalation routes, offering flexibility in clinical applications. Its well-characterized mechanism and reliable efficacy make it a valuable therapeutic agent in respiratory medicine.
Metaproterenol hemisulfate structure
Metaproterenol hemisulfate structure
Product Name:Metaproterenol hemisulfate
CAS No:5874-97-5
MF:C22H36N2O10S
MW:520.5936460495
MDL:MFCD00058303
CID:46234
PubChem ID:329750377
Update Time:2025-10-19

Metaproterenol hemisulfate Chemical and Physical Properties

Names and Identifiers

    • Orciprenaline sulfate
    • 3,5-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol sulfate (2:1)
    • Metaproterenol hemisulfate
    • Alupent
    • Metaproterenol Sulfate
    • Metaproterenol Hemis
    • Metaproterenol Hemisulfate Salt
    • Orciprenaline hemisulfate
    • NCGC00015655-09
    • BCP13601
    • Benzyl alcohol, 3,5-dihydroxy-alpha-((isopropylamino)methyl)-, sulfate (2:1) (salt)
    • SCHEMBL41815
    • AKOS015994757
    • DTXSID4045391
    • Orciprenaline for system suitability
    • HMS3713F11
    • METAPROTERENOL SULFATE [USP-RS]
    • Metaproterenol sulfate, United States Pharmacopeia (USP) Reference Standard
    • rac-5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol sulfate (2:1)
    • 1,3-BENZENEDIOL, 5-(1-HYDROXY-2-(1-METHYLETHYL)AMINO)ETHYL-, (+/-)-, SULPHATE (2:1) (SALT)
    • METAPROTERENOL SULFATE [USP MONOGRAPH]
    • HMS1569F11
    • 1,3-Benzenediol, 5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, Sulfate(2:1)(Salt)
    • ORCIPRENALINE SULFATE [JAN]
    • (+/-)-3,5-DIHYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL SULFATE (2:1)
    • CHEMBL1568057
    • 5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol hemisulfate
    • EINECS 227-539-6
    • Metaproterenol sulfate;Th-152; Th 152; Th152
    • HMS3262C10
    • rac-5-(1-hydroxy-2-(propan-2-ylamino)ethyl)benzene-1,3-diol sulfate (2:1)
    • Tox21_500734
    • ORCIPRENALINE SULFATE (MART.)
    • NCGC00261419-01
    • CCG-222038
    • LP00734
    • CAS-5874-97-5
    • bis(5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol) sulfate
    • ORCIPRENALINE SULFATE [EP MONOGRAPH]
    • EN300-50867
    • ORCIPRENALINE SULFATE [MART.]
    • Metaproterenol sulfate (USAN:USP)
    • NCGC00016662-01
    • 1,3-BENZENEDIOL, 5-(1-HYDROXY-2-(1-METHYLETHYL)AMINO)ETHYL-, (+/-)-, SULFATE (2:1) (SALT)
    • Q27279120
    • Orciprenaline sulphate
    • (+/-)-3,5-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL SULPHATE (2:1)
    • 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethane sulfate
    • SW198971-2
    • F82060
    • 1,3-Benzenediol, 5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, sulfate (2:1) salt
    • Metaproterenol (hemisulfate)
    • Prometa
    • 3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate
    • CCG-220505
    • Metaproterenol sulfate, orciprenaline sulfate
    • M 2398
    • MFCD00058303
    • FT-0628263
    • D00685
    • 1-(3,5-Dihydroxyphenyl)-2-(isopropylamino)ethanol sulfate
    • (+-)-Orciprenaline sulfate
    • 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol;sulfuric acid
    • (+-)-3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate (2:1)
    • rac-bis(N-(2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)propan-2-aminium) sulfate
    • (+/-)-3,5-DIHYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL SULPHATE (2:1)
    • Z955123630
    • Metaproterenol sulphate
    • bis(5-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,3-diol); sulfuric acid
    • METAPROTERENOL SULFATE [VANDF]
    • SR-01000872665
    • EU-0100734
    • Tox21_110551_1
    • METAPROTERENOL SULFATE [MI]
    • GJ20H50YF0
    • METAPROTERENOL SULFATE (USP-RS)
    • racemic orciprenaline sulfate
    • Metaproterenol sulfate (USP)
    • ORCIPRENALINE SULFATE (EP MONOGRAPH)
    • 3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate (2:1)
    • 5874-97-5
    • CHEBI:83332
    • HMS2096F11
    • Prestwick_845
    • TH-152
    • (RS)-orciprenaline sulfate
    • ORCIPRENALINE SULFATE [WHO-DD]
    • Orciprenaline (hemisulfate)
    • Novasmasol
    • Metaproterenol sulfate [USAN]
    • Orciprenaline sulfate, European Pharmacopoeia (EP) Reference Standard
    • Orciprenaline for system suitability, European Pharmacopoeia (EP) Reference Standard
    • rac-orciprenaline sulfate
    • NCGC00094078-01
    • SS-4263
    • Orciprenaline sulfate (JP17)
    • DTXCID2025391
    • (+/-)-3,5-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL SULFATE (2:1)
    • Tox21_110551
    • Alupent (TN)
    • SR-01000872665-1
    • 5-((1RS)-1-Hydroxy-2-((1-methylethyl)amino)ethyl)benzene-1,3-diol hemisulfate
    • UNII-GJ20H50YF0
    • METAPROTERENOL SULFATE (USP MONOGRAPH)
    • METAPROTERENOL SULFATE [ORANGE BOOK]
    • DB-053257
    • Orciprenaline sulfate (JP18)
    • MKFFGUZYVNDHIH-UHFFFAOYSA-N
    • MDL: MFCD00058303
    • Inchi: 1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)
    • InChI Key: MKFFGUZYVNDHIH-UHFFFAOYSA-N
    • SMILES: S(=O)(=O)(O)O.OC(C1C=C(C=C(C=1)O)O)CNC(C)C.OC(C1C=C(C=C(C=1)O)O)CNC(C)C

Computed Properties

  • Exact Mass: 520.20900
  • Monoisotopic Mass: 520.20906652g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 10
  • Hydrogen Bond Acceptor Count: 12
  • Heavy Atom Count: 35
  • Rotatable Bond Count: 8
  • Complexity: 258
  • Covalently-Bonded Unit Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 228?2

Experimental Properties

  • Color/Form: NA
  • Melting Point: 202-203°
  • PSA: 228.42000
  • LogP: 3.46820

Metaproterenol hemisulfate Security Information

Metaproterenol hemisulfate Pricemore >>

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Metaproterenol hemisulfate Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5874-97-5)Metaproterenol hemisulfate
Order Number:A1033686
Stock Status:in Stock
Quantity:500mg
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 16:52
Price ($):248.0
Recommended suppliers
Amadis Chemical Company Limited
(CAS:5874-97-5)Metaproterenol hemisulfate
A1033686
Purity:99%
Quantity:500mg
Price ($):248.0
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