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  Chang Wen,Xin Jiang,Kun Wu,Ruiqiang Luo,Qinghan Li RSC Adv. 2020 10 19610
• 2. Facile attachment of functional moieties to crosslinked polystyrene beads via robust linkages: Suzuki reactions using polymer-supported boronic acids
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• 3. Reductive coupling of halogenothiophenes and halogenothiazoles catalysed by PdII in a basic alcohol medium
  Yang Xie,Geok Kheng Tan,Yaw Kai Yan,Jagadese J. Vittal,Siu Choon Ng,T. S. Andy Hor J. Chem. Soc. Dalton Trans. 1999 773
• 4. Selective and efficient synthesis of trans-arylvinylboronates and trans-hetarylvinylboronates using palladium catalyzed cross-coupling
  Zhihao Liu,Wei Wei,Lu Xiong,Qiang Feng,Yaojie Shi,Ningyu Wang,Luoting Yu New J. Chem. 2017 41 3172
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• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Aryl halides Aryl bromides
• Solvents and Organic Chemicals Organic Compounds Heterocyclic Compounds

Comprehensive Guide to 2-Bromofuran (CAS No. 584-12-3): Properties, Applications, and Industry Insights

2-Bromofuran (CAS No. 584-12-3) is a halogenated furan derivative that has garnered significant attention in organic synthesis and pharmaceutical research. This compound, characterized by its bromine substitution at the 2-position of the furan ring, serves as a versatile building block for complex molecular architectures. With the growing demand for heterocyclic compounds in drug discovery, 2-Bromofuran has become a focal point for researchers exploring novel synthetic pathways.

The molecular structure of 2-Bromofuran combines the reactivity of bromine with the aromaticity of the furan ring, making it valuable for cross-coupling reactions like Suzuki-Miyaura and Stille couplings. Recent studies highlight its role in developing bioactive molecules, particularly in antimicrobial and anti-inflammatory agents. As sustainability gains traction in chemical manufacturing, greener synthesis methods for brominated furans are being investigated, aligning with the industry's shift toward eco-friendly protocols.

Analytical techniques such as GC-MS and NMR spectroscopy are routinely employed to verify the purity of CAS No. 584-12-3. Storage recommendations typically emphasize protection from light and moisture to maintain stability. Researchers frequently search for "2-Bromofuran solubility" or "safety data for 584-12-3," reflecting practical concerns in laboratory handling. The compound’s low melting point (≈20°C) necessitates controlled temperature conditions during transport.

In material science, 2-Bromofuran derivatives contribute to conductive polymers and OLED materials. A 2023 Journal of Materials Chemistry study demonstrated its utility in creating π-conjugated systems for flexible electronics—a hot topic amidst the wearable technology boom. This application dovetails with searches for "halogenated furans in electronics" and "CAS 584-12-3 suppliers," indicating cross-industry interest.

Regulatory compliance remains crucial when working with 2-Bromofuran. While not classified as hazardous under standard protocols, proper PPE (gloves, goggles) is advised during manipulation. The compound’s vapor pressure (0.3 mmHg at 25°C) warrants adequate ventilation—a detail often queried in "584-12-3 handling precautions" searches. Recent patents disclose improved purification methods addressing trace impurities, reflecting quality demands from end-users.

Market trends show rising 2-Bromofuran consumption in Asia-Pacific research hubs, driven by pharmaceutical outsourcing. Analytical databases reveal increased queries for "alternative to 2-bromofuran" and "scalable synthesis 584-12-3," pointing to supply chain optimization needs. As AI-assisted molecular design accelerates, this compound’s role in fragment-based drug discovery continues to expand, with computational studies predicting new structure-activity relationships.

• 32460-00-7(2,5-Dibromofuran (>85%))
• 2600399-92-4(2,5-dibromofuran-3,4-d2)
• 2600399-52-6(2-bromofuran-3,4,5-d3)
• 53599-35-2(2-Brom-5-deuteriumfuran)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)