Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides?
Chemical Communications Pub Date: 2014-07-24 DOI: 10.1039/C4CC05307A
Abstract
An efficient room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl bromides is presented. The Pd(OAc)2/NiXantphos-based catalyst enables the introduction of various aryl and heteroaryl groups, via a deprotonative cross-coupling process (DCCP) in good to excellent yields (60–99%).
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4