Cas no 56-40-6 (Glycine)

Glycine is an amino acid with a wide range of applications in various industries. Its unique properties make it an ideal chelating agent, stabilizer, and additive in pharmaceuticals, cosmetics, and food products. It also serves as a precursor to other important compounds, offering versatility in manufacturing processes.
Glycine structure
Glycine structure
Product Name:Glycine
CAS No:56-40-6
MF:C2H5NO2
MW:75.066600561142
MDL:MFCD00008131
CID:33622
PubChem ID:750
Update Time:2025-07-14

Glycine Chemical and Physical Properties

Names and Identifiers

    • 2-Aminoacetic acid
    • BLOTTING BUFFER
    • TG BUFFER
    • TRIS-GLYCINE
    • TRIS-GLYCINE BUFFER
    • TRIS GLYCINE BUFFER CONCENTRATE
    • TRIS-GLYCINE RUNNING BUFFER
    • TRIS-TRICINE BUFFER
    • TT BUFFER
    • Acetic acid, amino-
    • Amino acid
    • amino-aceticaci
    • Aminoessigsαure
    • Aminoethanoecacid
    • Amitone
    • Athenon
    • component of Corilin
    • Glicoamin
    • L-Glycine
    • Glycine [for Electrophoresis]
    • Aminoacetic acid
    • Aminoacetic acid,medicinal
    • Glycine
    • GLYCINE(RG)
    • H-Gly-OH
    • aminomethylcarboxylic acid
    • carboxymethylamine
    • GLYCINEULTRAPURE
    • Glycocoll
    • Gly
    • Iconyl
    • Monazol
    • Additive Screening Solution 47
    • Kit-No 78374
    • Pilose Asiabell Root Extract
    • Additive Screening Solution 47/Kit-No 78374
    • 甘氨酸
    • Glycinate
    • Aminoethanoic acid
    • Glycolixir
    • Glycosthene
    • Aciport
    • Padil
    • Hampshire glycine
    • Leimzucker
    • Aminoazijnzuur
    • Glycine, non-medical
    • Sucre de gelatine
    • Gyn-hydralin
    • GLY (IUPAC abbrev)
    • Glycinum
    • Glyzin
    • Corilin
    • Glycinum [INN-Latin]
    • Glicina [INN-Spanish]
    • Glycine [INN]
    • Glykokoll
    • Acidum aminoaceticum [INN-Latin]
    • Acido aminoacetico [INN-Spanish]
    • Acide aminoacetique [INN-French]
    • FEMA No. 3287
    • CC
    • Aminoethanoate
    • Glicina (INN-Spanish)
    • NSC-25936
    • AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
    • Biomol-NT_000195
    • MFCD00008131
    • B72BA06C-60E9-4A83-A24A-A2D7F465BB65
    • CS-B1641
    • Tox21_113575
    • Glycine, purum, >=98.5% (NT)
    • AI3-04085
    • Acide aminoacetique (INN-French)
    • H2N-CH2-COOH
    • NSC 25936
    • amino-Acetic acid
    • CAREDO Repair Cracked Teeth Toothpastes100g
    • 2-Aminoacetic acid;Aminoacetic acid
    • 1ST1408
    • [3H]glycine
    • GLYCINE [JAN]
    • GLYCINE [EP MONOGRAPH]
    • CCRIS 5915
    • CAREDO Treating Gingivitis Toothpastes100g
    • GLYCINE [ORANGE BOOK]
    • UNII-TE7660XO1C
    • Q-201300
    • CAS-56-40-6
    • BP-31024
    • Glycine (USP:INN)
    • GTPL4084
    • NSC760120
    • GLYCINE (USP-RS)
    • D70890
    • EC 200-272-2
    • Glycine iron sulphate (1:1)
    • D00011
    • AZD4282
    • Q620730
    • Acide aminoacetique
    • Glycine, United States Pharmacopeia (USP) Reference Standard
    • GLYCINE [FCC]
    • bmse000977
    • 2-aminoacetate
    • CAREDO Treating Gingivitis Toothpastes
    • InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5
    • Glycine (JP18/USP)
    • HY-Y0966
    • CCG-266010
    • WLN: Z1VQ
    • Glycine, free base
    • NH2CH2COOH
    • BPBio1_001222
    • GLYCINE [USP MONOGRAPH]
    • L-Glycine,(S)
    • Glycine, labeled with carbon-14
    • Corilin (Salt/Mix)
    • Glycine, tested according to Ph.Eur.
    • Acido aminoacetico (INN-Spanish)
    • Gly-CO
    • GLYCINE [FHFI]
    • DB-029870
    • amino-Acetate
    • NCGC00024503-03
    • GLYCINE (MART.)
    • Glycine, BioUltra, >=99.0% (NT)
    • AB-131/40217813
    • 56-40-6
    • BRD-K72369578-001-04-1
    • Glycine, 99%, natural, FCC, FG
    • Glycine, analytical standard, for nitrogen determination according to Kjeldahl method
    • Acidum aminoaceticum (INN-Latin)
    • HSDB 495
    • DTXCID90667
    • 2-aminoaceticacid
    • C22407
    • 25718-94-9
    • Glycine, >=99.0% (NT)
    • BDBM18133
    • Gly-OH
    • EINECS 200-272-2
    • GLYCINE [MI]
    • Glycine 1000 microg/mL in Water
    • aminoacetate
    • GLYCINE [GREEN BOOK]
    • C-Terminal [mycofactocin precursor peptide]-glycine
    • Glicina
    • Hgly
    • GLYCINE [VANDF]
    • GTPL4635
    • L-Gly
    • GTPL727
    • Glycine, European Pharmacopoeia (EP) Reference Standard
    • GLYCINE-1-13C-15N
    • bmse000089
    • CHEMBL773
    • Glycine, for electrophoresis, >=99%
    • Q27115084
    • Acido aminoacetico
    • Glycine, ReagentPlus(R), >=99% (HPLC)
    • BCP25965
    • STL194276
    • DTXSID9020667
    • Glycine, Pharmaceutical Secondary Standard; Certified Reference Material
    • SR-01000597729
    • Aminoessigsaure
    • GLYCINE [USP-RS]
    • Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, >=98.5%
    • Aminoessigsaeure
    • GLYCINE [HSDB]
    • Z955123660
    • Glycine, meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)
    • GLYCINE [WHO-DD]
    • s4821
    • GLYCINE [II]
    • CHEBI:15428
    • H-Gly
    • EN300-19731
    • L001246
    • Glycine, BioUltra, for molecular biology, >=99.0% (NT)
    • Pharmakon1600-01300021
    • AKOS000119626
    • Glycine, Electrophoresis Grade
    • Glycine, 98.5-101.5%
    • Glycine, ACS reagent, >=98.5%
    • C00037
    • SERINE IMPURITY B [EP IMPURITY]
    • GLYCINE (EP MONOGRAPH)
    • Tox21_113575_1
    • Glycine [USP:INN]
    • NSC-760120
    • Glycine, >=99%
    • Tocris-0219
    • TE7660XO1C
    • HB0299
    • GLYCINE [MART.]
    • Treating Gingivitis Toothpaste
    • Glycine, Vetec(TM) reagent grade, 98%
    • NS00001575
    • NCGC00024503-01
    • Glycine (H-Gly-OH)
    • GLYCINE (USP MONOGRAPH)
    • NCGC00024503-02
    • [14C]-glycine
    • Repair Cracked Teeth Toothpaste
    • CAREDO Repair Cracked Teeth Toothpastes
    • DB00145
    • Glycine, EP/USP
    • NSC25936
    • Glycinum (INN-Latin)
    • M03001
    • Glycine, BioXtra, >=99% (titration)
    • Gly-253
    • Acidum aminoaceticum
    • [14C]glycine
    • G0317
    • G0099
    • Glycine, 99%, FCC
    • GLYCINE (II)
    • 18875-39-3
    • SR-01000597729-1
    • GLYCINE 1.5% IN PLASTIC CONTAINER
    • Glycine USP grade
    • F2191-0197
    • Glycine, SAJ special grade, >=99.0%
    • Glycine - Absolute carbon isotope ratio
    • Glycine, certified reference material, TraceCERT(R)
    • FG175750
    • Glycine, from non-animal source, suitable for cell culture
    • EAA89676
    • FG02717
    • Glycine (Standard)
    • HY-Y0966R
    • Glycine - EP
    • 200-272-2
    • Glycine, technical grade
    • FG71510
    • MSK1408
    • MDL： MFCD00008131
    • Inchi： 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
    • InChI Key： DHMQDGOQFOQNFH-UHFFFAOYSA-N
    • SMILES： NCC(=O)O
    • BRN： 635782

Computed Properties

  • Exact Mass: 75.03200
  • Monoisotopic Mass: 75.032
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 5
  • Rotatable Bond Count: 1
  • Complexity: 42.9
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -3.2
  • Topological Polar Surface Area: 63.3
  • Molecular Weight: 75.07

Experimental Properties

  • Color/Form: White monoclinic or hexagonal crystals, or white crystalline powder. Odorless, with special sweet taste.
  • Density: 1.03?g/mL?at 20?°C
  • Melting Point: 240?°C (dec.) (lit.)
  • Boiling Point: 233 oC
  • Flash Point: 176.67°C
  • Refractive Index: 1.4264 (estimate)
  • PH: 4(0.2 molar aqueous solution)
  • Solubility: H2O: 100?mg/mL
  • Water Partition Coefficient: 25 g/100 mL (25 oC)
  • Stability/Shelf Life: Stable. Combustible. Incompatible with strong oxidizing agents.
  • PSA: 63.32000
  • LogP: -0.27000
  • Odor: Odorless
  • Solubility: Soluble in water, slightly soluble in pyridine, solubility in water
  • Merck: 4491
  • FEMA: 3287 | GLYCINE
  • pka: 2.35(at 25℃)

Glycine Security Information

Glycine Customs Data

  • HS CODE：29224910
  • Customs Data：

    China Customs Code:

    29224910

Glycine Pricemore >>

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Glycine Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Ammonium chloride Solvents: Water ;  3 - 30 d, 38 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  24 h, 110 °C
Reference
New Insights into the Characterization of 'Insoluble Black HCN Polymers'
Ruiz-Bermejo, Marta; de la Fuente, Jose L.; Rogero, Celia; Menor-Salvan, Cesar; Osuna-Esteban, Susana; et al, Chemistry & Biodiversity, 2012, 9(1), 25-40

Glycine Preparation Products

Glycine Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:56-40-6)Glycine
Order Number:LE6424;LE5679155;LE18663
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:49
Price ($):discuss personally
Amadis Chemical Company Limited
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(CAS:56-40-6)Glycine
Order Number:A20662
Stock Status:in Stock
Quantity:5kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:10
Price ($):509.0
Suzhou Senfeida Chemical Co., Ltd
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(CAS:56-40-6)Glycine
Order Number:sfd12098
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally
Shanghai Jinhuan Chemical CO., LTD.
Gold Member
Audited Supplier Audited Supplier
(CAS:56-40-6)Glycine
Order Number:JH025
Stock Status:in Stock
Quantity:25kg
Purity:98.00%
Pricing Information Last Updated:Monday, 8 January 2024 17:37
Price ($): negotiated

Glycine Spectrogram

GC-MS
GC-MS
13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Glycine Related Literature

Related Categories

Additional information on Glycine

Glycine (56-40-6): Chemical Properties and Biological Significance in Biomedicine

Glycine, with the CAS number 56-40-6, is the simplest amino acid and a fundamental building block in protein synthesis. Its molecular structure (NH?-CH?-COOH) allows it to act as a neurotransmitter in the central nervous system, influencing cognitive health and neurological disorders. Researchers have extensively studied its role in metabolic pathways, particularly in the synthesis of glutathione, a potent antioxidant. In the pharmaceutical industry, Glycine is utilized as a buffering agent in drug formulations, enhancing the stability of biologics like monoclonal antibodies. Its low toxicity and high solubility make it a preferred excipient in intravenous therapies and oral medications. Recent studies also highlight its potential in mitigating oxidative stress, a key factor in aging and chronic diseases.

Glycine (56-40-6) in Drug Development and Therapeutic Applications

The versatility of Glycine (56-40-6) extends to its therapeutic applications, particularly in neuroprotection and wound healing. Clinical trials have demonstrated its efficacy in reducing ischemic brain injury by modulating NMDA receptors, a breakthrough for stroke treatment. Additionally, Glycine’s anti-inflammatory properties are being explored for conditions like arthritis and sepsis. In regenerative medicine, it accelerates collagen production, making it valuable in dermal repair formulations. The rise of personalized medicine has further amplified interest in Glycine as a biomarker for metabolic syndromes. Pharmaceutical companies are investing in Glycine derivatives to develop next-generation immunomodulators and chemo-adjuvants, aligning with the demand for targeted therapies.

Safety and Regulatory Status of Glycine (56-40-6) in Pharmaceuticals

Glycine’s (56-40-6) safety profile is well-documented, with approvals from the FDA, EMA, and other global agencies for use in drugs and supplements. Its GRAS (Generally Recognized as Safe) status underscores its low risk of adverse effects, even at high doses. However, rigorous quality control is essential to avoid contaminants in synthetic Glycine batches. Regulatory guidelines emphasize compliance with GMP standards for pharmaceutical-grade Glycine, ensuring purity >99%. Emerging debates focus on its interaction with other amino acids in parenteral nutrition, prompting further pharmacokinetic studies. As consumers prioritize clean-label ingredients, Glycine’s natural occurrence in foods like bone broth reinforces its appeal in nutraceuticals.

The integration of Glycine (56-40-6) into biotechnology and AI-driven drug discovery is reshaping its applications. Computational models predict Glycine’s potential in enzyme engineering, optimizing industrial biocatalysts for greener chemistry. Startups are leveraging CRISPR to engineer Glycine-producing microbes, addressing supply chain challenges. In precision oncology, Glycine metabolism is being targeted to starve cancer cells of nutrients—a strategy known as metabolic reprogramming. The compound’s role in mitochondrial health is also gaining traction, with startups exploring Glycine-based therapies for neurodegenerative diseases like Alzheimer’s. As biohacking gains popularity, Glycine supplements are marketed for sleep optimization and muscle recovery, tapping into the consumer wellness boom.

56-40-6 (Glycine) Related Products

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:56-40-6)Glycine
LE6424;LE5679155;LE18663
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Email
Amadis Chemical Company Limited
(CAS:56-40-6)Glycine
A20662
Purity:99%
Quantity:5kg
Price ($):509.0
Email