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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide (CAS No. 52963-33-4): A Comprehensive Overview

The compound 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide (CAS No. 52963-33-4) is a significant molecule in the field of organic chemistry, particularly within the realm of heterocyclic compounds. This compound, characterized by its unique structure and functional groups, has garnered attention due to its potential applications in drug discovery, material science, and other advanced chemical research areas.

Structure and Properties: The molecule consists of a pyridine ring with substituents at positions 2, 3, and 5. Specifically, the 2-position bears an amino group (-NH?), the 5-position contains a bromine atom (-Br), and the 3-position is substituted with a carboxylic acid group (-COOH). The hydrobromide salt form indicates that the compound exists as a bromide ion pair with the protonated amine group. This structure imparts unique electronic properties, making it suitable for various chemical reactions and applications.

Synthesis and Characterization: Recent studies have focused on optimizing the synthesis of 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide. Researchers have explored various methodologies, including substitution reactions and coupling techniques, to enhance yield and purity. Advanced characterization techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography have been employed to confirm the molecular structure and stability of this compound.

Applications in Drug Discovery: The presence of multiple functional groups in 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide makes it an attractive candidate for medicinal chemistry research. The amino group can act as a hydrogen bond donor, while the bromine atom introduces electron-withdrawing effects, potentially influencing bioavailability and receptor interactions. Recent studies suggest that this compound may exhibit potential as a lead molecule in anti-inflammatory or anticancer drug development.

Role in Material Science: Beyond pharmacology, 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide has shown promise in material science applications. Its structural features make it suitable for use in coordination chemistry, where it can serve as a ligand in metal complexes. Additionally, its electronic properties render it useful in the development of novel materials for optoelectronic devices.

Recent Research Advances: In line with current trends in chemical research, recent studies have delved into the reactivity and stability of 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide under various conditions. For instance, investigations into its thermal decomposition kinetics have provided insights into its suitability for high-temperature applications. Furthermore, computational chemistry models have been utilized to predict its interaction with biological targets, paving the way for future experimental validations.

Conclusion: 2-Amino-5-bromo-pyridine-3-carboxylic acid hydrobromide (CAS No. 52963-33-4) stands out as a versatile compound with multifaceted applications across diverse scientific domains. Its unique structure and functional groups position it as a valuable tool in both academic research and industrial applications. As ongoing research continues to uncover new potentials for this compound, its significance in the chemical sciences is expected to grow further.

• 5345-47-1(2-aminopyridine-3-carboxylic acid)
• 180340-69-6(6-amino-5-bromopyridine-3-carboxylic acid)
• 335031-01-1((2-amino-5-bromopyridin-3-yl)methanol)
• 532440-94-1(2-Amino-5-methylnicotinic acid)
• 443956-55-6(2-Amino-5-bromo-3-(hydroxymethyl)pyridine hydrobromide)
• 89795-70-0(2-aminopyridine-3,5-dicarboxylic acid)
• 50735-34-7(methyl 2-amino-5-bromopyridine-3-carboxylate)
• 52833-94-0(2-amino-5-bromo-pyridine-3-carboxylic acid)
• 59414-89-0(3-Pyridinecarboxylicacid, 2-amino-5-bromo-4-methyl-, hydrobromide (1:1))
• 180340-70-9(methyl 6-amino-5-bromo-pyridine-3-carboxylate)