Cas no 496808-01-6 (1-2-(Dipropylamino)ethylpiperazine)

1-2-(Dipropylamino)ethylpiperazine is a specialized organic compound featuring a piperazine core substituted with a dipropylaminoethyl group. This structure imparts unique reactivity and versatility, making it valuable in pharmaceutical synthesis and fine chemical applications. Its secondary amine functionality allows for further derivatization, enabling its use as an intermediate in the development of bioactive molecules or catalysts. The compound's balanced lipophilicity, conferred by the propyl groups, enhances solubility in organic media, facilitating its incorporation into synthetic workflows. Careful handling is advised due to potential amine-related hazards. Its well-defined structure ensures consistent performance in targeted reactions, supporting precise molecular design.
1-2-(Dipropylamino)ethylpiperazine structure
496808-01-6 structure
Product Name:1-2-(Dipropylamino)ethylpiperazine
CAS No:496808-01-6
MF:C12H27N3
MW:213.362882852554
MDL:MFCD00191215
CID:92899
PubChem ID:2736329
Update Time:2025-06-12

1-2-(Dipropylamino)ethylpiperazine Chemical and Physical Properties

Names and Identifiers

    • 1-(2-Di-n-propylaminoethyl)piperazine
    • 1-[2-(Dipropylamino)ethyl]piperazine
    • N-(2-piperazin-1-ylethyl)-N-propylpropan-1-amine
    • (2-piperazinylethyl)dipropylamine
    • 1-(2-dipropylaminoethyl)piperazine
    • 1-(2-Dipropylaminoethyl)-Piperazine
    • AC1MC5CC
    • AC1Q2XQH
    • ACMC-1APVN
    • N-(2-piperazin-1-ylethyl)-N-propyl-propan-1-amine
    • 1-[2-(dipropylamino)-ethyl]-piperazine
    • 496808-01-6
    • MFCD00191215
    • WUA80801
    • AKOS002663695
    • CS-0314021
    • 1-(2-Dipropylaminoethyl)-piperazine, AldrichCPR
    • N-[2-(Piperazin-1-yl)ethyl]-N-propylpropan-1-amine
    • N-[2-(1-piperazinyl)ethyl]-N-propyl-1-propanamine
    • NQRQMDMOABSDEK-UHFFFAOYSA-N
    • 1-Piperazineethanamine,N,N-dipropyl-
    • AS-44264
    • DTXSID00371282
    • SCHEMBL972101
    • FT-0644753
    • A827797
    • 1[2-(Dipropylamino)ethyl]piperazine
    • N-(2-(Piperazin-1-yl)ethyl)-N-propylpropan-1-amine
    • DB-051665
    • A10355
    • 1-2-(Dipropylamino)ethylpiperazine
    • MDL: MFCD00191215
    • Inchi: 1S/C12H27N3/c1-3-7-14(8-4-2)11-12-15-9-5-13-6-10-15/h13H,3-12H2,1-2H3
    • InChI Key: NQRQMDMOABSDEK-UHFFFAOYSA-N
    • SMILES: N1(CCNCC1)CCN(CCC)CCC

Computed Properties

  • Exact Mass: 213.22000
  • Monoisotopic Mass: 213.22
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 7
  • Complexity: 138
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1.4
  • Topological Polar Surface Area: 18.5A^2

Experimental Properties

  • Color/Form: liquid
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 72 °C
  • Flash Point: 109.0±13.1 °C
  • Refractive Index: 1.469
  • PSA: 18.51000
  • LogP: 1.28030
  • Solubility: Not determined
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

1-2-(Dipropylamino)ethylpiperazine Security Information

1-2-(Dipropylamino)ethylpiperazine Customs Data

  • HS CODE:2933599090
  • Customs Data:

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-2-(Dipropylamino)ethylpiperazine Pricemore >>

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Additional information on 1-2-(Dipropylamino)ethylpiperazine

Professional Introduction to Compound with CAS No. 496808-01-6 and Product Name: 1-2-(Dipropylamino)ethylpiperazine

1-2-(Dipropylamino)ethylpiperazine, identified by the Chemical Abstracts Service Number (CAS No.) 496808-01-6, is a significant compound in the field of pharmaceutical chemistry and biochemistry. This piperazine derivative has garnered attention due to its unique structural properties and potential applications in drug development. The compound features a piperazine ring substituted with a dipropylaminoethyl side chain, which contributes to its distinct chemical behavior and biological activity.

The molecular structure of 1-2-(Dipropylamino)ethylpiperazine encompasses a nitrogen-rich framework, which is a hallmark of many bioactive molecules. The presence of the dipropylamino group enhances the compound's lipophilicity, making it more soluble in organic solvents and potentially facilitating its interaction with biological targets. This feature is particularly relevant in the design of drugs that require efficient absorption and distribution within the body.

Recent research has highlighted the potential of 1-2-(Dipropylamino)ethylpiperazine as a scaffold for developing novel therapeutic agents. Studies have demonstrated its ability to modulate various biological pathways, including neurotransmitter systems and inflammatory responses. The compound's structural similarity to known pharmacophores has prompted investigations into its role as an intermediate in synthesizing more complex molecules with enhanced pharmacological properties.

In the realm of medicinal chemistry, the synthesis of 1-2-(Dipropylamino)ethylpiperazine involves multi-step organic reactions that require precise control over reaction conditions. Advanced synthetic methodologies, such as catalytic hydrogenation and nucleophilic substitution, have been employed to achieve high yields and purity. These techniques ensure that the final product meets the stringent standards required for pharmaceutical applications.

The biological activity of 1-2-(Dipropylamino)ethylpiperazine has been explored in several preclinical studies. Researchers have investigated its effects on enzymes and receptors involved in pain perception, addiction, and neurodegenerative diseases. Preliminary findings suggest that this compound may exhibit potent activity in modulating these pathways, making it a promising candidate for further development into therapeutic drugs.

One of the most intriguing aspects of 1-2-(Dipropylamino)ethylpiperazine is its potential to serve as a lead compound for drug discovery programs. By leveraging computational modeling and high-throughput screening techniques, scientists can identify derivatives of this molecule that exhibit improved efficacy and reduced side effects. Such approaches are integral to modern drug development pipelines, where rapid identification of promising candidates is crucial.

The pharmacokinetic profile of 1-2-(Dipropylamino)ethylpiperazine is another critical area of study. Understanding how the compound is absorbed, distributed, metabolized, and excreted (ADME) provides essential insights into its potential therapeutic utility. Advanced analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, have been utilized to characterize the compound's metabolic pathways and interactions with biological systems.

Future research directions for 1-2-(Dipropylamino)ethylpiperazine include exploring its role in combination therapies. By pairing this compound with other bioactive molecules, researchers aim to develop synergistic treatments that address multiple aspects of diseases simultaneously. This strategy is particularly relevant in tackling complex conditions such as cancer and neurodegenerative disorders, where multifaceted approaches are often necessary.

The regulatory landscape for pharmaceutical compounds like 1-2-(Dipropylamino)ethylpiperazine is stringent but well-defined. Compliance with guidelines set forth by agencies such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) ensures that these compounds are safe and effective before reaching clinical use. Regulatory submissions typically involve comprehensive data on chemical synthesis, physicochemical properties, toxicology, and pharmacology.

In conclusion, 1-2-(Dipropylamino)ethylpiperazine (CAS No. 496808-01-6) represents a compelling subject of study in pharmaceutical chemistry. Its unique structural features and potential biological activities make it a valuable candidate for drug development efforts. As research continues to uncover new applications for this compound, it is likely to play an increasingly important role in the discovery and design of novel therapeutic agents.

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