Cas no 4553-24-6 (3-(4-Propylpiperazin-1-yl)propan-1-amine)

3-(4-Propylpiperazin-1-yl)propan-1-amine is a tertiary amine compound featuring a propyl-substituted piperazine core linked to a propylamine chain. This structure imparts versatility in synthetic applications, particularly as an intermediate in pharmaceutical and agrochemical research. The propylpiperazine moiety enhances lipophilicity, potentially improving membrane permeability in bioactive molecules. Its bifunctional design allows for further derivatization at both the amine and piperazine sites, enabling tailored modifications for target-specific applications. The compound’s stability under standard conditions and compatibility with common organic solvents facilitate its use in multistep syntheses. It is particularly valuable in developing CNS-targeting agents due to the pharmacophore’s resemblance to neurologically active scaffolds.

3-(4-Propylpiperazin-1-yl)propan-1-amine structure

4553-24-6 structure

Product Name:3-(4-Propylpiperazin-1-yl)propan-1-amine

CAS No:4553-24-6

MF:C₁₀H₂₃N₃

MW:185.309722185135

MDL:MFCD06740355

CID:325581

PubChem ID:7175937

Update Time:2025-05-20

3-(4-Propylpiperazin-1-yl)propan-1-amine Chemical and Physical Properties

Names and Identifiers

- 1-Piperazinepropanamine,4-propyl-
- 3-(4-Propylpiperazin-1-yl)propan-1-amine
- 3-(4-PROPYL-PIPERAZIN-1-YL)-PROPYLAMINE
- 1-Piperazinepropanamine,4-propyl
- 3-(4-propylpiperazinyl)propylamine
- 4-Propyl-1-piperazinepropanamine
- 1-(3-Aminopropyl)-4-propylpiperazine
- AKOS000123089
- AB01332162-02
- 4553-24-6
- MFCD06740355
- LS-02127
- CS-0297862
- NCGC00340394-01
- EN300-231784
- SCHEMBL1861653
- [3-(4-propylpiperazin-1-yl)propyl]amine
- DTXSID20428328
- MDL： MFCD06740355
- Inchi： 1S/C10H23N3/c1-2-5-12-7-9-13(10-8-12)6-3-4-11/h2-11H2,1H3
- InChI Key： DJOXCABHIQUIJR-UHFFFAOYSA-N
- SMILES： N1(CCCN)CCN(CCC)CC1

Computed Properties

Exact Mass: 185.18900
Monoisotopic Mass: 185.189197746g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 13
Rotatable Bond Count: 5
Complexity: 119
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: nothing
Topological Polar Surface Area: 32.5?2

Experimental Properties

PSA: 32.50000
LogP: 0.93890

3-(4-Propylpiperazin-1-yl)propan-1-amine Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

3-(4-Propylpiperazin-1-yl)propan-1-amine Customs Data

HS CODE：2933599090
Customs Data：

China Customs Code:
2933599090

Overview:

2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-(4-Propylpiperazin-1-yl)propan-1-amine Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Fluorochem	029690-1g	3-(4-Propyl-piperazin-1-yl)-propylamine	4553-24-6		1g	￡205.00	2022-03-01
Fluorochem	029690-5g	3-(4-Propyl-piperazin-1-yl)-propylamine	4553-24-6		5g	￡715.00	2022-03-01
Fluorochem	029690-10g	3-(4-Propyl-piperazin-1-yl)-propylamine	4553-24-6		10g	￡1225.00	2022-03-01
TRC	P226895-250mg	3-(4-Propylpiperazin-1-yl)propan-1-amine	4553-24-6		250mg	$ 185.00	2022-06-02
TRC	P226895-500mg	3-(4-Propylpiperazin-1-yl)propan-1-amine	4553-24-6		500mg	$ 300.00	2022-06-02
TRC	P226895-1000mg	3-(4-Propylpiperazin-1-yl)propan-1-amine	4553-24-6		1g	$ 480.00	2022-06-02
Chemenu	CM296188-1g	3-(4-Propyl-piperazin-1-yl)-propylamine	4553-24-6	95%	1g	$185	2022-09-29
abcr	AB405845-500 mg	3-(4-Propylpiperazin-1-yl)propan-1-amine, 95%; .	4553-24-6	95%	500MG	€195.40	2023-02-03
abcr	AB405845-1 g	3-(4-Propylpiperazin-1-yl)propan-1-amine, 95%; .	4553-24-6	95%	1g	€239.00	2023-04-25
abcr	AB405845-5 g	3-(4-Propylpiperazin-1-yl)propan-1-amine, 95%; .	4553-24-6	95%	5g	€656.50	2023-04-25

3-(4-Propylpiperazin-1-yl)propan-1-amine Suppliers

Amadis Chemical Company Limited

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(CAS:4553-24-6)3-(4-Propylpiperazin-1-yl)propan-1-amine

Order Number:A1161232

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 00:05

Price ($):151.0

Email:[email protected]

Product Official Link

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Additional information on 3-(4-Propylpiperazin-1-yl)propan-1-amine

Comprehensive Overview of 3-(4-Propylpiperazin-1-yl)propan-1-amine (CAS No. 4553-24-6)

3-(4-Propylpiperazin-1-yl)propan-1-amine, identified by its CAS number 4553-24-6, is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, characterized by its unique piperazine and propylamine structure, is frequently explored for its potential applications in drug development, particularly in the design of central nervous system (CNS) targeting agents. Researchers are increasingly interested in its role as a building block for bioactive molecules, owing to its versatile reactivity and ability to modulate receptor interactions.

The growing demand for neuropharmacological compounds has placed 3-(4-Propylpiperazin-1-yl)propan-1-amine in the spotlight. Recent studies highlight its relevance in synthesizing dopamine and serotonin receptor modulators, which are critical for treating conditions like anxiety, depression, and neurodegenerative diseases. Its structural flexibility allows for fine-tuning of pharmacokinetic properties, making it a valuable candidate for medicinal chemistry applications. Additionally, its low toxicity profile and high bioavailability further enhance its appeal in preclinical research.

From an industrial perspective, CAS 4553-24-6 is often utilized as an intermediate in the synthesis of more complex pharmaceutical ingredients. Its compatibility with various cross-coupling reactions and amine functionalization techniques makes it a preferred choice for chemists. The compound’s stability under standard laboratory conditions also ensures consistent performance in high-throughput screening and combinatorial chemistry workflows. These attributes align with the current trend toward green chemistry, as researchers seek sustainable and efficient synthetic pathways.

One of the most frequently asked questions about 3-(4-Propylpiperazin-1-yl)propan-1-amine revolves around its synthetic accessibility. The compound can be prepared via straightforward N-alkylation reactions, often employing propylamine and piperazine derivatives as starting materials. Optimization of reaction conditions, such as temperature and solvent selection, can significantly improve yield and purity. This ease of synthesis has contributed to its widespread adoption in academic and industrial labs alike.

Another area of interest is the compound’s potential in drug repurposing. With the rise of computational chemistry and AI-driven drug discovery, 4553-24-6 has been flagged as a candidate for investigating new therapeutic avenues. Virtual screening tools have identified its scaffold as a potential fit for G-protein-coupled receptors (GPCRs), which are pivotal in numerous physiological processes. This aligns with the broader scientific community’s focus on precision medicine and targeted therapies.

In summary, 3-(4-Propylpiperazin-1-yl)propan-1-amine (CAS 4553-24-6) represents a multifaceted compound with substantial promise in pharmaceutical innovation. Its structural features, synthetic versatility, and biological relevance make it a subject of ongoing research. As the scientific community continues to explore its applications, this compound is poised to play a pivotal role in advancing neuropharmacology and drug development.

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