Production Method 1

53-59-8

50-99-7

136592-00-2

477259-60-2

526-95-4

53-57-6

Reaction Conditions

1.1C:9028-12-0, C:9028-53-9, S:H2O, S:DMSO, 4 h, 30°C, pH 7.5

Reference

Application of biocatalysis towards asymmetric reduction and hydrolytic desymmetrisation in the synthesis of a β-3 receptor agonist

By Badland, Matthew et al, Green Chemistry, 2011, 13(10), 2888-2894

(1R)-2-chloro-1-(6-chloro-3-pyridyl)ethanol Raw materials

• NADP
• D(+)-Glucose
• 2-Chloro-1-(6-chloropyridin-3-yl)ethanone

(1R)-2-chloro-1-(6-chloro-3-pyridyl)ethanol Preparation Products

• D-Gluconic acid (526-95-4)
• NADPH (53-57-6)
• (1R)-2-chloro-1-(6-chloro-3-pyridyl)ethanol (477259-60-2)

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