Cas no 459-60-9 (1-fluoro-4-methoxybenzene)
1-Fluoro-4-methoxybenzene is a fluorinated aromatic compound characterized by the presence of a fluorine atom and a methoxy group on the benzene ring at para positions. This structure imparts unique electronic and steric properties, making it a valuable intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. The fluorine atom enhances metabolic stability and lipophilicity, while the methoxy group contributes to electron-donating effects, influencing reactivity in substitution reactions. Its high purity and well-defined reactivity profile make it suitable for use in cross-coupling reactions, nucleophilic aromatic substitutions, and as a building block for more complex molecules. The compound is typically handled under standard laboratory conditions with appropriate safety precautions.
1-fluoro-4-methoxybenzene structure
Product Name:1-fluoro-4-methoxybenzene
CAS No:459-60-9
MF:C7H7FO
MW:126.128285646439
MDL:MFCD00000348
CID:37557
PubChem ID:9987
Update Time:2025-05-28
1-fluoro-4-methoxybenzene Chemical and Physical Properties
Names and Identifiers
-
- p-Fluoroanisole
- 4-Fluoroanisole
- 1-Fluoro-4-methoxybenzene
- 4-Floroanisole
- 4-Fluoranisol
- 4-fluoranisole
- 4-FLUOROANISOL
- 4-Fluoro-anisole
- 4-fluoromethoxybenzene
- 4-methoxyfluorobenzene
- Anisole,p-fluoro
- para-fluoroanisole
- p-fluoroanisol
- F0231
- F0001-1244
- CK1195
- 4-Fluoro-1-methoxybenzene
- 4-Methoxyphenyl fluoride
- W-106105
- p-Methoxyfluorobenzene
- Benzene, 1-fluoro-4-methoxy-
- MFCD00000348
- Anisole, p-fluoro-
- 1-fluoro-4-methoxy-benzene
- p-Fluoromethoxybenzene
- 1219802-94-4
- AKOS005259464
- CS-W016565
- 4-Fluoroanisole--d4
- 459-60-9
- Z53834743
- NSC 4672
- SCHEMBL12015227
- NSC4672
- 4-Fluorophenyl methyl ether
- AM20040516
- PD065658
- NSC-4672
- SCHEMBL8298
- DTXSID3060033
- AI3-10595
- p-Fluorophenyl methyl ether
- EN300-16113
- FT-0618503
- Q63395414
- EINECS 207-295-7
- NS00044112
- 4-Fluoroanisole, 99%
- A826944
- F6A62M57LM
- BCP24441
- PS-9186
- DB-024091
- 207-295-7
- Anisole, p-fluoro-(8CI)
- 1-fluoro-4-methoxybenzene
-
- MDL： MFCD00000348
- Inchi： 1S/C7H7FO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3
- InChI Key： VIPWUFMFHBIKQI-UHFFFAOYSA-N
- SMILES： FC1C=CC(=CC=1)OC
- BRN： 1281425
Computed Properties
- Exact Mass: 126.04800
- Monoisotopic Mass: 126.048093
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 77
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 9.2
Experimental Properties
- Color/Form: Colorless Transparent Liquid
- Density: 1.114?g/mL?at 25?°C(lit.)
- Melting Point: ?45?°C (lit.)
- Boiling Point: 157°C
- Flash Point: Fahrenheit: 109.4 ° f
Celsius: 43 ° c - Refractive Index: n20/D 1.488(lit.)
- Water Partition Coefficient: Not miscible or difficult to mix in water.
- PSA: 9.23000
- LogP: 1.83430
- Solubility: Not determined
1-fluoro-4-methoxybenzene Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H226
-
Warning Statement：
P210,P241,P280,P303
P361
P353,P403
P235,P501a - Hazardous Material transportation number：UN 3271 3/PG 3
- WGK Germany：3
- Hazard Category Code： 10
- Safety Instruction： S16
-
Hazardous Material Identification：
- Storage Condition：Flammable area
- HazardClass：3
- PackingGroup：III
- TSCA：T
- Safety Term：3
- Packing Group：III
- Risk Phrases：R10
- Packing Group：III
- Hazard Level：3
1-fluoro-4-methoxybenzene Customs Data
- HS CODE：2909309090
- Customs Data：
China Customs Code:
2909309090Overview:
2909309090 Other aromatic ethers and their halogenated derivatives\sulfonation\Nitrated derivative(Including nitrosative derivatives).Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
1-fluoro-4-methoxybenzene Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 001698-1g |
4-Fluoroanisole |
459-60-9 | 99% | 1g |
￡10.00 | 2022-03-01 | |
| Fluorochem | 001698-25g |
4-Fluoroanisole |
459-60-9 | 99% | 25g |
￡13.00 | 2022-03-01 | |
| Fluorochem | 001698-250g |
4-Fluoroanisole |
459-60-9 | 99% | 250g |
￡29.00 | 2022-03-01 | |
| Fluorochem | 001698-500g |
4-Fluoroanisole |
459-60-9 | 99% | 500g |
￡49.00 | 2022-03-01 | |
| Fluorochem | 001698-1kg |
4-Fluoroanisole |
459-60-9 | 99% | 1kg |
￡84.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | F123675-100g |
1-fluoro-4-methoxybenzene |
459-60-9 | ≥99.0% | 100g |
￥264.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | F123675-25g |
1-fluoro-4-methoxybenzene |
459-60-9 | ≥99.0% | 25g |
￥73.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | F123675-500g |
1-fluoro-4-methoxybenzene |
459-60-9 | ≥99.0% | 500g |
￥1056.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | F123675-5g |
1-fluoro-4-methoxybenzene |
459-60-9 | ≥99.0% | 5g |
￥29.90 | 2023-09-02 | |
| Alichem | A015000225-250mg |
4-Fluoroanisole |
459-60-9 | 97% | 250mg |
$480.00 | 2023-09-01 |
1-fluoro-4-methoxybenzene Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:459-60-9)4-Fluoroanisole
Order Number:sfd5933
Stock Status:in Stock
Quantity:200KG
Purity:99%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Email:[email protected]
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier
(CAS:459-60-9)
Order Number:SFD951
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Wednesday, 11 December 2024 17:02
Price ($):
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:459-60-9)對(duì)氟苯甲醚
Order Number:LE19395883
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:48
Price ($):discuss personally
Email:[email protected]
1-fluoro-4-methoxybenzene Related Literature
-
Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
-
Jason Wan Lab Chip, 2020,20, 4528-4538
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