Cas no 442910-29-4 (2-(bromomethyl)-4-methyl-pyridine)

2-(Bromomethyl)-4-methyl-pyridine is a versatile brominated pyridine derivative commonly employed as an intermediate in organic synthesis and pharmaceutical manufacturing. Its reactive bromomethyl group facilitates efficient alkylation and functionalization reactions, making it valuable for constructing complex heterocyclic compounds. The compound's stability under standard handling conditions and compatibility with a range of solvents enhance its utility in nucleophilic substitution and cross-coupling reactions. The presence of the methyl group at the 4-position can influence regioselectivity in subsequent transformations. Suitable for use in research and industrial applications, it is particularly relevant in the development of agrochemicals, pharmaceuticals, and specialty chemicals. Proper storage under inert conditions is recommended to maintain reactivity.
2-(bromomethyl)-4-methyl-pyridine structure
442910-29-4 structure
Product Name:2-(bromomethyl)-4-methyl-pyridine
CAS No:442910-29-4
MF:C7H8BrN
MW:186.049120903015
MDL:MFCD16607563
CID:1030407
PubChem ID:21874622
Update Time:2025-11-02

2-(bromomethyl)-4-methyl-pyridine Chemical and Physical Properties

Names and Identifiers

    • 2-(Bromomethyl)-4-methylpyridine
    • 2-(bromomethyl)-4-methyl-pyridine
    • SB53664
    • AC9733
    • EN300-1914642
    • SY253139
    • 442910-29-4
    • SCHEMBL4048883
    • DTXSID70619229
    • MFCD16607563
    • CZTCOXQVCBNPKF-UHFFFAOYSA-N
    • DA-05816
    • 2-Bromomethyl-4-methylpyridine
    • A872562
    • GS4050
    • MDL: MFCD16607563
    • Inchi: 1S/C7H8BrN/c1-6-2-3-9-7(4-6)5-8/h2-4H,5H2,1H3
    • InChI Key: CZTCOXQVCBNPKF-UHFFFAOYSA-N
    • SMILES: BrCC1C=C(C)C=CN=1

Computed Properties

  • Exact Mass: 184.98404
  • Monoisotopic Mass: 184.98401g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 1
  • Complexity: 85
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.8
  • Topological Polar Surface Area: 12.9?2

Experimental Properties

  • PSA: 12.89

2-(bromomethyl)-4-methyl-pyridine Pricemore >>

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Additional information on 2-(bromomethyl)-4-methyl-pyridine

Comprehensive Guide to 2-(Bromomethyl)-4-methyl-pyridine (CAS No. 442910-29-4): Properties, Applications, and Market Insights

2-(Bromomethyl)-4-methyl-pyridine (CAS No. 442910-29-4) is a versatile brominated pyridine derivative widely used in pharmaceutical synthesis, agrochemical production, and material science. This compound, characterized by its reactive bromomethyl group and methyl-substituted pyridine ring, serves as a crucial building block in organic chemistry. Researchers and industry professionals frequently search for "2-(Bromomethyl)-4-methyl-pyridine uses," "CAS 442910-29-4 synthesis," and "4-methyl-pyridine derivatives," reflecting its growing importance in specialized applications.

The molecular structure of 2-(Bromomethyl)-4-methyl-pyridine features a pyridine core with two strategic functional groups: a bromomethyl moiety at the 2-position and a methyl group at the 4-position. This arrangement enables diverse chemical transformations, making it valuable for creating heterocyclic compounds and pharmaceutical intermediates. Current trends in drug discovery have increased interest in "pyridine-based building blocks" and "bromomethyl functionalization," positioning this compound as a key material in modern synthetic chemistry.

In pharmaceutical applications, 2-(Bromomethyl)-4-methyl-pyridine serves as a precursor for various active pharmaceutical ingredients (APIs). Its ability to undergo nucleophilic substitution reactions makes it particularly useful in creating alkylated pyridine derivatives, which are common structural motifs in many drugs. Recent searches for "pyridine derivatives in drug development" and "CAS 442910-29-4 in medicinal chemistry" highlight the compound's relevance to current research in targeted therapies and small molecule drugs.

The agrochemical industry utilizes 2-(Bromomethyl)-4-methyl-pyridine in the synthesis of crop protection agents and pesticide intermediates. Its structural features contribute to the development of compounds with improved biological activity and environmental stability. With growing global concerns about "sustainable agriculture" and "green chemistry," researchers are exploring modified pyridine derivatives that offer enhanced efficacy with reduced ecological impact.

Material scientists employ 2-(Bromomethyl)-4-methyl-pyridine in the creation of functional polymers and coordination complexes. The compound's bromomethyl group facilitates polymerization reactions and serves as an anchor point for creating metal-organic frameworks (MOFs). Recent interest in "pyridine-based materials" and "advanced functional materials" has driven innovation in this application area, particularly for catalysis and molecular recognition systems.

From a synthetic chemistry perspective, 2-(Bromomethyl)-4-methyl-pyridine offers several advantages. The electron-deficient pyridine ring directs electrophilic attacks to specific positions, while the bromomethyl group provides a handle for further functionalization. These properties make it valuable for creating complex molecular architectures, as evidenced by increasing searches for "pyridine functionalization techniques" and "heterocyclic compound synthesis."

The global market for 2-(Bromomethyl)-4-methyl-pyridine reflects its growing importance across multiple industries. Suppliers and manufacturers have noted increased demand for "high purity pyridine derivatives" and "custom chemical synthesis" services. Quality control parameters typically include HPLC purity, moisture content, and residual solvent levels, with analytical methods frequently searched including "GC-MS analysis of pyridine compounds" and "NMR characterization of bromomethyl derivatives."

Safety considerations for handling 2-(Bromomethyl)-4-methyl-pyridine emphasize standard laboratory precautions. Proper personal protective equipment (PPE) and ventilation systems are recommended when working with this compound. The scientific community continues to develop "greener synthetic methods" and "alternative bromination techniques" to improve the sustainability of producing such valuable intermediates.

Future research directions for 2-(Bromomethyl)-4-methyl-pyridine applications include exploration in bioconjugation chemistry and click chemistry methodologies. The compound's potential in creating targeted drug delivery systems and diagnostic agents aligns with current trends in "precision medicine" and "theranostic applications." These emerging applications demonstrate the ongoing relevance of this versatile pyridine derivative in cutting-edge scientific research.

In conclusion, 2-(Bromomethyl)-4-methyl-pyridine (CAS No. 442910-29-4) represents a strategically important compound with wide-ranging applications in pharmaceuticals, agrochemicals, and advanced materials. Its unique combination of reactivity and structural features continues to inspire innovation across multiple scientific disciplines, addressing current challenges in "sustainable chemistry" and "molecular design." As research progresses, this compound will likely maintain its position as a valuable tool for chemical synthesis and product development.

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