• 1. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
• 2. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
• 3. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502
• 4. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
• 5. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes

Comprehensive Overview of 3-(4-Nitrophenyl)-1,2-Oxazole (CAS No. 4264-05-5): Properties, Applications, and Research Insights

The compound 3-(4-nitrophenyl)-1,2-oxazole (CAS No. 4264-05-5) is a heterocyclic organic molecule featuring an oxazole ring linked to a 4-nitrophenyl group. This structure endows it with unique chemical properties, making it a subject of interest in pharmaceutical research, material science, and synthetic chemistry. Its molecular formula (C₉H₆N₂O₃) and molecular weight (190.16 g/mol) are critical for analytical applications, while its nitro group contributes to its reactivity in electrophilic substitutions.

Recent studies highlight the role of 3-(4-nitrophenyl)-1,2-oxazole as a building block in drug discovery, particularly in designing kinase inhibitors and antimicrobial agents. Researchers are exploring its potential in cancer therapy, leveraging its ability to modulate cellular pathways. Additionally, its fluorescence properties have sparked interest in sensor development, aligning with the growing demand for environmental monitoring tools.

From a synthetic perspective, the compound’s crystallinity and thermal stability make it suitable for optoelectronic materials. Its nitro-aromatic moiety facilitates photoinduced electron transfer, a feature exploited in organic LEDs and photovoltaic devices. These applications resonate with current trends in green energy and sustainable technology.

Analytical techniques like HPLC, NMR, and mass spectrometry are routinely employed to characterize CAS 4264-05-5. Purity thresholds (>98%) are crucial for industrial use, driving advancements in chromatographic separation methods. The compound’s solubility in polar solvents (e.g., DMSO, ethanol) further expands its utility in formulation chemistry.

In academia, 3-(4-nitrophenyl)oxazole serves as a model substrate for studying cycloaddition reactions and catalysis. Its structure-activity relationships (SAR) are frequently cited in medicinal chemistry literature, addressing common search queries like "oxazole derivatives in drug design" or "nitrophenyl compounds for sensors". This aligns with the surge in AI-driven drug discovery discussions.

Regulatory compliance for 4264-05-5 focuses on safe handling and storage, though it is not classified as hazardous under major frameworks. Its biodegradability profile is under investigation, reflecting broader concerns about chemical sustainability. Suppliers often provide technical data sheets (TDS) to ensure transparency.

Future research may explore 3-(4-nitrophenyl)-1,2-oxazole’s role in nanotechnology, particularly in drug delivery systems. Its compatibility with bioconjugation techniques could bridge gaps in targeted therapies. As the scientific community prioritizes molecular diversity, this compound’s versatility positions it as a key player in interdisciplinary innovation.

• 449181-21-9(Isoxazole, 5-ethyl-3-(3-nitrophenyl)- (9CI))
• 30213-79-7(5-Methyl-3-(4-nitrophenyl)isoxazole)
• 5301-03-1(5-Bromomethyl-3-(3-nitrophenyl)-isoxazole)
• 605663-76-1(3-(4-Nitro-Phenyl)-Isoxazol-5-Yl-Methanol)
• 112606-69-6(5-Nitro-3-(p-tolyl)benzo[d]isoxazole)
• 31108-56-2(Isoxazole, 3-(4-nitrophenyl)-5-phenyl-)
• 926316-89-4(5-Methyl-3-(2-nitrophenyl)isoxazole)
• 927188-96-3(5-Bromomethyl-3-(4-nitrophenyl)-isoxazole)
• 119162-48-0(3-(4-Nitrophenyl)-1,2-oxazol-5-amine)
• 887591-64-2(3-(3-Nitrophenyl)isoxazol-5-amine)