• 1. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
  Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
• 2. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324
• 3. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 4. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 5. An antioxidative galactomannan extracted from Chinese Sesbania cannabina enhances immune activation of macrophage cells?
  Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes

5-Methyl-3-(2-nitrophenyl)isoxazole: A Comprehensive Overview

5-Methyl-3-(2-nitrophenyl)isoxazole, also known by its CAS number CAS No. 926316-89-4, is a compound of significant interest in the field of organic chemistry and pharmacology. This compound belongs to the class of isoxazoles, which are five-membered heterocyclic compounds containing one oxygen and one nitrogen atom. The structure of 5-Methyl-3-(2-nitrophenyl)isoxazole features a methyl group at the 5-position and a nitro-substituted phenyl group at the 3-position, making it a unique derivative with potential applications in drug discovery and material science.

The synthesis of 5-Methyl-3-(2-nitrophenyl)isoxazole involves a series of well-established organic reactions, including nucleophilic substitution, condensation, and oxidation processes. Recent advancements in catalytic methods have enabled more efficient and selective syntheses of this compound, reducing production costs and enhancing its scalability for industrial applications. Researchers have also explored green chemistry approaches to synthesize this compound, minimizing environmental impact while maintaining high yields.

In terms of chemical properties, 5-Methyl-3-(2-nitrophenyl)isoxazole exhibits notable stability under various conditions, making it suitable for use in diverse chemical environments. Its electronic properties, influenced by the electron-withdrawing nitro group and the electron-donating methyl group, contribute to its reactivity in different reaction systems. These properties have been leveraged in the development of new materials, such as sensors and catalysts, where precise control over electronic characteristics is crucial.

The biological activity of 5-Methyl-3-(2-nitrophenyl)isoxazole has been extensively studied in recent years. Preclinical studies have demonstrated its potential as an anti-inflammatory agent, with promising results in reducing inflammation markers in experimental models. Additionally, this compound has shown selective cytotoxicity against certain cancer cell lines, suggesting its potential role in anticancer therapy. Ongoing research is focused on optimizing its pharmacokinetic properties to enhance bioavailability and reduce adverse effects.

In the realm of material science, 5-Methyl-3-(2-nitrophenyl)isoxazole has found applications as a precursor for advanced polymers and coatings. Its ability to form stable covalent bonds with other functional groups makes it a valuable building block for designing materials with tailored mechanical and thermal properties. Recent breakthroughs in polymer chemistry have enabled the incorporation of this compound into high-performance composites, which are being tested for use in aerospace and automotive industries.

The environmental impact of 5-Methyl-3-(2-nitrophenyl)isoxazole has also been a topic of interest among researchers. Studies on its biodegradation pathways have provided insights into its persistence in natural ecosystems. Efforts are underway to develop eco-friendly methods for its disposal and recycling, ensuring that its use aligns with sustainable development goals.

In conclusion, 5-Methyl-3-(2-nitrophenyl)isoxazole, with its unique chemical structure and versatile properties, continues to be a focal point in both academic research and industrial applications. As new findings emerge from ongoing studies, this compound is poised to play an even greater role in advancing fields such as medicine, materials science, and environmental technology.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)