Cas no 4143-62-8 (3',4'-Dimethoxyflavone)

3',4'-Dimethoxyflavone is a synthetic flavonoid derivative characterized by the presence of methoxy groups at the 3' and 4' positions of its phenyl ring. This compound exhibits notable biological activity, particularly as an inhibitor of cytochrome P450 enzymes, which may be useful in modulating drug metabolism pathways. Its structural features contribute to enhanced stability and bioavailability compared to non-substituted flavonoids. Research applications include investigations into its potential antioxidative, anti-inflammatory, and neuroprotective properties. The methoxy substitutions improve lipophilicity, facilitating membrane permeability. Analytical methods such as HPLC and LC-MS are typically employed for purity assessment. This compound serves as a valuable reference standard in pharmacological and biochemical studies.

3',4'-Dimethoxyflavone structure

Product Name:3',4'-Dimethoxyflavone

CAS No:4143-62-8

MF:C₁₇H₁₄O₄

MW:282.290665149689

MDL:MFCD00143009

CID:84940

PubChem ID:354333484

Update Time:2025-06-07

3',4'-Dimethoxyflavone Chemical and Physical Properties

Names and Identifiers

- 3',4'-Dimethoxyflavone
- 3,4-Dimethoxyflavone
- 3'.4'-Dimethoxyflavone
- 3′,4′-Dimethoxyflavone
- DIMETHOXYFLAVONE, 3',4'-(RG)
- 2-(3,4-Dimethoxyphenyl)chromen-4-one
- 3′,4′-DMF
- 2-(3,4-dimethoxyphenyl)-4H-chromen-4-one
- 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-
- KBio2_004087
- 3',4'-DMF
- PubChem9847
- Spectrum_001039
- SpecPlus_000555
- Spectrum2_000709
- 2-(3,4-dimethoxyphenyl)-4h-chromen-4-on
- Spectrum5_000546
- Spectrum4_001893
- 3',4' - Dimethoxyflavone
- Oprea1_098805
- KBioGR_002451
- KBioSS_001519
- SPECTRUM1500735
- DivK1c_006651
- SPBio_00089
- 2-(3,4-Dimethoxy-phenyl)-chromen-4-one
- SPBio_000897
- 3-,4--DIMETHOXYFLAVONE
- 4143-62-8
- KBio2_001519
- CCG-40034
- D4794
- SDCCGMLS-0066648.P001
- SCHEMBL1675954
- NCGC00095629-01
- SR-01000471680
- SR-01000471680-1
- SY050121
- CHEMBL91153
- 3 inverted exclamation mark ,4 inverted exclamation mark -Dimethoxyflavone
- AN-829/41499278
- A825556
- AKOS002279678
- LS-14554
- DTXSID50350946
- ZGHORMOOTZTQFL-UHFFFAOYSA-N
- HY-N8572
- MFCD00143009
- FT-0614346
- KBio2_006655
- KBio1_001595
- PD171572
- CS-0148635
- T70897
- BDBM50420209
- STK899809
- DTXCID20302013
- MDL： MFCD00143009
- Inchi： 1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3
- InChI Key： ZGHORMOOTZTQFL-UHFFFAOYSA-N
- SMILES： O1C2C=CC=CC=2C(C=C1C1C=CC(=C(C=1)OC)OC)=O
- BRN： 236749

Computed Properties

Exact Mass: 282.08900
Monoisotopic Mass: 282.089209
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 21
Rotatable Bond Count: 3
Complexity: 417
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 3.5
Topological Polar Surface Area: 44.8

Experimental Properties

Density: 1.242±0.06 g/cm3 (20 oC 760 Torr),
Melting Point: 151.0 to 155.0 deg-C
Boiling Point: 428.5°C at 760 mmHg
Flash Point: 190.6°C
Refractive Index: 1.598
Solubility: Almost insoluble (0.025 g/l) (25 o C),
PSA: 48.67000
LogP: 3.47720
λmax: 334(MeOH)(lit.)

3',4'-Dimethoxyflavone Security Information

Symbol:
Signal Word：Danger
Hazard Statement： H301
Warning Statement： P301 + P310
Hazardous Material transportation number：UN 2811 6.1 / PGIII
WGK Germany：3
Hazard Category Code： 25
Safety Instruction： S22-S24/25
RTECS：DJ3012950
Hazardous Material Identification：
Storage Condition：room temp
Safety Term：S22;S24/25

3',4'-Dimethoxyflavone Customs Data

HS CODE：2914509090
Customs Data：

China Customs Code:
2914509090

Overview:

2914509090 Ketones containing other oxygen-containing groups. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

Declaration elements:

Product Name, component content, use to, Acetone declared packaging

Summary:

HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

3',4'-Dimethoxyflavone Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Chemenu	CM285439-5g	2-(3,4-Dimethoxyphenyl)-4H-chromen-4-one	4143-62-8	95%	5g	$698	2021-06-17
ChemScence	CS-0148635-100mg	3',4'-Dimethoxyflavone	4143-62-8	98.76%	100mg	$84.0	2022-04-27
ChemScence	CS-0148635-250mg	3',4'-Dimethoxyflavone	4143-62-8	98.76%	250mg	$140.0	2022-04-27
ChemScence	CS-0148635-1g	3',4'-Dimethoxyflavone	4143-62-8	98.76%	1g	$283.0	2022-04-27
SHANG HAI TAO SHU Biotechnology Co., Ltd.	TN2883-25 mg	3',4'-Dimethoxyflavone	4143-62-8		25mg	￥882.00	2022-04-26
TRC	D460513-25mg	3',4'-Dimethoxyflavone	4143-62-8		25mg	$ 50.00	2022-06-05
TRC	D460513-50mg	3',4'-Dimethoxyflavone	4143-62-8		50mg	$ 65.00	2022-06-05
TRC	D460513-200mg	3',4'-Dimethoxyflavone	4143-62-8		200mg	$ 185.00	2022-06-05
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	D870986-200mg	3',4'-Dimethoxyflavone	4143-62-8	98%	200mg	￥439.20	2022-01-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.	D4794-200mg	3',4'-Dimethoxyflavone	4143-62-8	98.0%(GC)	200mg	￥395.0	2022-06-10

3',4'-Dimethoxyflavone Production Method

3',4'-Dimethoxyflavone Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:4143-62-8)3',4'-Dimethoxyflavone

Order Number:LE17700

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:16

Price ($):discuss personally

Email:[email protected]

3',4'-Dimethoxyflavone Related Literature

1. Exploring the anti-breast cancer potential of flavonoid analogs

Vanrajsinh Thakor,Mayur Poddar,Sumit Dey,S. N. Manjula,SubbaRao V. Madhunapantula,Rahul Pawara,Harun M. Patel,Malleshappa N. Noolvi RSC Adv. 2016 6 79166
2. A versatile approach to flavones via a one-pot Pd(ii)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones

Jun Lee,Jihyun Yu,Seung Hwan Son,Jinyuk Heo,Taelim Kim,Ji-Young An,Kyung-Soo Inn,Nam-Jung Kim Org. Biomol. Chem. 2016 14 777
3. Rh-Catalyzed aldehydic C–H alkynylation and annulation

Maddali L. N. Rao,Boddu S. Ramakrishna Org. Biomol. Chem. 2020 18 1402
4. A novel one-pot synthesis of flavones

Meng-Yang Chang,Min-Chen Tsai,Chun-Yi Lin RSC Adv. 2021 11 11655
5. A structure activity relationship study of 3,4′-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus

Alexander W. Weig,Patrick M. O'Conner,Jakub M. Kwiecinski,Orry M. Marciano,Angelica Nunag,Andrew T. Gutierrez,Roberta J. Melander,Alexander R. Horswill,Christian Melander Org. Biomol. Chem. 2023 21 3373

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