A novel one-pot synthesis of flavones?

RSC Advances Pub Date: 2021-03-22 DOI: 10.1039/D1RA00534K

Abstract

In this paper, a one-pot facile route for the BiCl3/RuCl3-mediated synthesis of functionalized flavones is described, including: (i) intermolecular ortho-acylation of substituted phenols with cinnamoyl chlorides, and (ii) intramolecular cyclodehydrogenation of the resulting o-hydroxychalcones. The reaction conditions are discussed herein.

Graphical abstract: A novel one-pot synthesis of flavones
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