A versatile approach to flavones via a one-pot Pd(ii)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones?
Organic & Biomolecular Chemistry Pub Date: 2015-11-13 DOI: 10.1039/C5OB01911G
Abstract
A variety of flavones were expediently synthesized from readily accessible chromanones via a one-pot sequence involving Pd(II)-catalyzed dehydrogenation and oxidative boron-Heck coupling with arylboronic acid pinacol esters. In particular, the use of arylboronic acid pinacol esters was found to significantly improve the yield of the reaction.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4