Cas no 389843-60-1 (3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester)

3-Furancarboxylic acid, 4-aminotetrahydro-, methyl ester is a specialized heterocyclic compound featuring both a furan ring and an amino group in a tetrahydro configuration. The methyl ester moiety enhances its solubility and reactivity, making it a versatile intermediate in organic synthesis. Its structural features, including the amino and ester functional groups, allow for further derivatization, enabling applications in pharmaceuticals, agrochemicals, and fine chemical production. The tetrahydrofuran core contributes to its stability while maintaining reactivity for selective transformations. This compound is particularly valuable in medicinal chemistry for the development of bioactive molecules due to its balanced lipophilicity and functional group compatibility.
3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester structure
389843-60-1 structure
Product Name:3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester
CAS No:389843-60-1
MF:C6H11NO3
MW:145.156441926956
MDL:MFCD19205816
CID:299106
PubChem ID:20729918
Update Time:2025-06-08

3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester Chemical and Physical Properties

Names and Identifiers

    • 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester
    • Methyl 4-aminotetrahydro-3-furancarboxylate
    • 2-amino-4-methylcarbamoyl-toluene
    • 4-amino-tetrahydro-furan-3-carboxylic acid methyl ester
    • Carbamic acid, (3-amino-4-methylphenyl)-, methyl ester
    • CTK1J1901
    • methyl 3-amino-4-methylcarbanilate
    • methyl 3-amino-4-tetrahydrofurancarboxylate
    • 4-Aminotetrahydrofuran-3-carboxylic acid methyl ester
    • 4-Aminotetrahydro-3-furancarboxylic acid methyl ester
    • CS-0183747
    • 3-Furancarboxylicacid,4-aminotetrahydro-,methylester,(3R,4S)-(9CI)
    • 362488-80-0
    • 3-Furancarboxylicacid,4-aminotetrahydro-,methylester(9CI)
    • SB36833
    • METHYL 4-AMINOOXOLANE-3-CARBOXYLATE
    • AKOS006340446
    • YQKCZMNEYIICEE-UHFFFAOYSA-N
    • SB36979
    • SCHEMBL3860384
    • (3R,4S)-4-Amino-tetrahydro-furan-3-carboxylic acid methyl ester
    • CGC56576
    • Methyl4-aminotetrahydrofuran-3-carboxylate
    • 3-furancarboxylic acid, 4-aminotetrahydro-, methyl ester, (3r,4s)-rel-, hydrochloride
    • 389843-60-1
    • Methyl 4-aminotetrahydrofuran-3-carboxylate
    • MDL: MFCD19205816
    • Inchi: 1S/C6H11NO3/c1-9-6(8)4-2-10-3-5(4)7/h4-5H,2-3,7H2,1H3
    • InChI Key: YQKCZMNEYIICEE-UHFFFAOYSA-N
    • SMILES: O1CC(C(C(=O)OC)C1)N

Computed Properties

  • Exact Mass: 145.07389321g/mol
  • Monoisotopic Mass: 145.07389321g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 137
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.6
  • Topological Polar Surface Area: 61.6?2

Experimental Properties

  • Density: 1.161
  • Boiling Point: 203 oC
  • Flash Point: 80 oC

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3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester Related Literature

Additional information on 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester

Comprehensive Overview of 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester (CAS No. 389843-60-1)

3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester (CAS No. 389843-60-1) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This compound, often referred to by its systematic name, belongs to the class of furan derivatives, which are known for their diverse biological activities and applications in drug discovery. The presence of both amino and ester functional groups in its structure makes it a versatile intermediate for synthesizing more complex molecules.

In recent years, the demand for furan-based compounds has surged due to their potential in developing novel therapeutics. Researchers are particularly interested in 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester for its role in creating bioactive molecules that target specific enzymes or receptors. Its unique structural features, including the tetrahydrofuran ring, contribute to its stability and bioavailability, making it a promising candidate for further studies.

The synthesis of 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester involves multi-step organic reactions, often starting from readily available furan precursors. Key steps include amination and esterification, which are critical for introducing the functional groups that define its chemical properties. Advanced techniques such as NMR spectroscopy and mass spectrometry are employed to characterize the compound, ensuring its purity and structural integrity.

One of the most searched questions related to this compound is: "What are the applications of 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester in drug development?" Current research highlights its potential as a building block for antiviral and anti-inflammatory agents. For instance, furan derivatives have shown activity against certain viral strains, sparking interest in their use for emerging infectious diseases. Additionally, the amino group in the compound allows for further modifications, enabling the design of targeted therapies.

Another trending topic is the green chemistry approach to synthesizing 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester. With growing environmental concerns, researchers are exploring catalytic methods and solvent-free reactions to reduce waste and energy consumption. This aligns with the broader industry shift toward sustainable chemical processes, which is a hot topic in academic and industrial circles.

From a commercial perspective, 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester is available through specialized chemical suppliers, often labeled as a research-grade chemical. Its price and availability can vary depending on the scale of production and purity requirements. Companies involved in custom synthesis frequently list this compound in their catalogs, catering to the needs of pharmaceutical and biotechnology firms.

In summary, 3-Furancarboxylic acid,4-aminotetrahydro-, methyl ester (CAS No. 389843-60-1) is a compound of significant scientific and industrial interest. Its structural complexity and functional versatility make it a valuable tool in medicinal chemistry and material science. As research continues to uncover new applications, this compound is likely to remain a focal point in the development of next-generation therapeutics and sustainable chemical solutions.

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