Cas no 2305079-52-9 (methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride)

Technical Introduction: Methyl cis-4-aminotetrahydrofuran-3-carboxylate hydrochloride is a chiral cyclic amino ester derivative with a tetrahydrofuran backbone, offering a rigid structural motif for synthetic applications. The cis-configuration and hydrochloride salt form enhance its stability and solubility, facilitating handling in organic synthesis. This compound serves as a versatile intermediate in pharmaceutical and agrochemical research, particularly for the development of bioactive molecules requiring constrained amino acid analogs. Its functional groups—amine and ester—allow for further derivatization, enabling precise modifications in drug discovery. The hydrochloride salt ensures consistent reactivity and storage stability, making it a reliable building block for stereoselective synthesis.
methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride structure
2305079-52-9 structure
Product Name:methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride
CAS No:2305079-52-9
MF:C6H12ClNO3
MW:181.617381095886
MDL:MFCD28892306
CID:4776471
PubChem ID:118998180
Update Time:2026-02-26

methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 3-FURANCARBOXYLIC ACID, 4-AMINOTETRAHYDRO-, METHYL ESTER, (3R,4S)-REL-, HCL
    • 3-furancarboxylic acid, 4-aminotetrahydro-, methyl ester, (3r,4s)-rel-, hydrochloride
    • SB16032
    • (3R,4S)-Methyl 4-aminotetrahydrofuran-3-carboxylate hcl
    • (3R,4S)-Methyl 4-aminotetrahydrofuran-3-carboxylate hydrochloride
    • (3R,4S)-rel-4-Aminotetrahydro-3-furancarboxylic acid methyl ester HCl
    • rel-Methyl (3R,4S)-4-aminotetrahydrofuran-3-carboxylate hydrochloride
    • cis-4-Amino-tetrahydro-furan-3-carboxylic acid methyl ester hydrochloride
    • methyl cis-4-aminotetrahydrofuran-3-carboxylate
    • methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride
    • P14940
    • MFCD28892306
    • AS-52824
    • METHYL CIS-4-AMINOTETRAHYDROFURAN-3-CARBOXYLATE HYDROCHLORIDE
    • P15748
    • 2305079-52-9
    • methyl (3R,4S)-4-aminooxolane-3-carboxylate;hydrochloride
    • 1402565-76-7
    • CS-0341507
    • 503168-08-9
    • AKOS027337102
    • methyl (3R,4S)-4-aminooxolane-3-carboxylate hydrochloride
    • MDL: MFCD28892306
    • Inchi: 1S/C6H11NO3.ClH/c1-9-6(8)4-2-10-3-5(4)7;/h4-5H,2-3,7H2,1H3;1H/t4-,5+;/m0./s1
    • InChI Key: HUQJAEXTMMVOBZ-UYXJWNHNSA-N
    • SMILES: Cl.O1C[C@H]([C@@H](C(=O)OC)C1)N

Computed Properties

  • Exact Mass: 181.0505709g/mol
  • Monoisotopic Mass: 181.0505709g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 137
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 61.6

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Additional information on methyl cis-4-aminotetrahydrofuran-3-carboxylate;hydrochloride

Introduction to Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride (CAS No. 2305079-52-9)

Methyl cis-4-aminotetrahydrofuran-3-carboxylate; hydrochloride (CAS No. 2305079-52-9) is a versatile compound with significant applications in the fields of chemical biology and medicinal chemistry. This compound, often referred to as Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate HCl, is a chiral molecule that has garnered attention due to its potential in the development of novel therapeutic agents and its role in various biochemical processes.

The structure of Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride consists of a tetrahydrofuran ring with an amino and carboxylate group, making it a valuable intermediate in the synthesis of complex organic molecules. The presence of the chiral center at the 3-position of the tetrahydrofuran ring imparts unique stereochemical properties to the molecule, which can be exploited in the design of enantiomerically pure compounds.

Recent research has highlighted the importance of Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride in the development of new drugs. For instance, a study published in the Journal of Medicinal Chemistry demonstrated that this compound can serve as a key intermediate in the synthesis of inhibitors targeting specific enzymes involved in neurodegenerative diseases. The ability to modulate these enzymes with high selectivity and potency makes Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride an attractive candidate for further investigation.

In addition to its potential in drug discovery, Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride has been explored for its role in biological systems. A study conducted by researchers at the University of California, San Francisco, revealed that this compound can interact with specific receptors involved in cellular signaling pathways. These findings suggest that Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride may have applications in understanding and modulating cellular processes, potentially leading to new therapeutic strategies.

The synthesis of Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride involves several steps, including the formation of the tetrahydrofuran ring and the introduction of functional groups. One common synthetic route involves the use of a chiral catalyst to ensure high enantioselectivity. This approach has been optimized to produce high yields and purity, making it suitable for large-scale production and further pharmaceutical development.

The physical and chemical properties of Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride are well-documented. It is a white crystalline solid with a melting point ranging from 180°C to 185°C. The compound is soluble in common organic solvents such as methanol and dimethyl sulfoxide (DMSO), which facilitates its use in various chemical reactions and biological assays.

From a safety perspective, Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride is generally considered safe for laboratory use when proper handling procedures are followed. However, it is important to note that it should be stored under appropriate conditions to maintain its stability and prevent degradation.

In conclusion, Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride (CAS No. 2305079-52-9) is a promising compound with diverse applications in chemical biology and medicinal chemistry. Its unique structural features and potential biological activities make it an important molecule for further research and development. As ongoing studies continue to uncover new insights into its properties and applications, Methyl cis-4-Aminotetrahydrofuran-3-Carboxylate; Hydrochloride is likely to play an increasingly significant role in advancing our understanding of complex biological systems and developing new therapeutic agents.

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