Cas no 37622-90-5 (Ethyl 1H-pyrazole-4-carboxylate)

Ethyl 1H-pyrazole-4-carboxylate is a versatile heterocyclic compound widely used as a key intermediate in pharmaceutical and agrochemical synthesis. Its pyrazole core structure enables diverse functionalization, making it valuable for constructing biologically active molecules. The ethyl ester group enhances solubility and reactivity, facilitating further derivatization under mild conditions. This compound exhibits high purity and stability, ensuring consistent performance in reactions such as condensations, cyclizations, and cross-coupling processes. Its compatibility with a range of reagents and conditions makes it a preferred choice for researchers developing novel active ingredients. The product is typically supplied with rigorous quality control to meet industry standards for synthetic applications.

Ethyl 1H-pyrazole-4-carboxylate structure

37622-90-5 structure

Product Name:Ethyl 1H-pyrazole-4-carboxylate

CAS No:37622-90-5

MF:C₆H₈N₂O₂

MW:140.139921188354

MDL:MFCD00010844

CID:54740

PubChem ID:142179

Update Time:2025-06-07

Ethyl 1H-pyrazole-4-carboxylate Chemical and Physical Properties

Names and Identifiers

- Ethyl 4-pyrazolecarboxylate
- Ethyl 4-pyarazolecarboxylate
- Ethyl 1H-pyrazole-4-carboxylate
- Ethyl Pyrazole-4-carboxylate
- 4-Pyrazolecarboxylic
- 4-Pyrazolecarboxylic Acid Ethyl Ester
- Ethyl 1H-pyrazole-4-carboxylate hydrochloride
- 1H-Pyrazole-4-Carboxylic Acid, Ethyl Ester
- Pyrazole-4-carboxylic Acid Ethyl Ester
- SY008759
- 4-ethoxycarbonylpyrazole
- 1H-Pyrazole-4-carboxylic acid ethyl ester
- ethyl 1H-pyrazol-4-carboxylate
- E0871
- 3-Ethyl-1H-pyrazole-4-carboxylic acid anion
- FT-0601059
- A1-08041
- CS-D1524
- 37622-90-5
- HY-100040
- NS00030231
- BB 0257389
- 4-ethoxycarbonyl-1H-pyrazole
- A6423
- PB25908
- PS-3638
- Ethyl 1H-pyrazole-4-carboxylate;Ethyl pyrazole-4-carboxylate;4-Ethoxycarbonylpyrazole
- F1905-7158
- ETHYL-4-PYRAZOLECARBOXYLATE
- STR08196
- ethyl 4-pyrazole carboxylate
- Ethyl 1 H-pyrazole-4-carboxylate
- ethyl4-pyrazolecarboxylate
- CHEMBL4461273
- Ethyl 4-pyrazolecarboxylate, 99%
- Z975817026
- BP-12629
- W-202545
- BCP21101
- GOJ
- SCHEMBL369224
- AM20100002
- ethyl 1~{H}-pyrazole-4-carboxylate
- DTXSID40191062
- MFCD00010844
- EN300-93017
- 4-(ethoxycarbonyl)pyrazole
- 1H-pyrazol-4-carboxylic acid ethyl ester
- AKOS005174209
- ethyl-1h-pyrazole-4-carboxylate
- AC-5977
- Ethyl pyrazole-4-carboxylate,98%
- BBL104305
- STL412483
- ALBB-013464
- DB-180878
- DB-005430
- MDL： MFCD00010844
- Inchi： 1S/C6H8N2O2/c1-2-10-6(9)5-3-7-8-4-5/h3-4H,2H2,1H3,(H,7,8)
- InChI Key： KACZQOKEFKFNDB-UHFFFAOYSA-N
- SMILES： O(C(C1C=NNC=1)=O)CC

Computed Properties

Exact Mass: 140.05900
Monoisotopic Mass: 140.058578
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 10
Rotatable Bond Count: 3
Complexity: 127
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 3
XLogP3: 0.4
Topological Polar Surface Area: 55

Experimental Properties

Color/Form: White to Yellow Solid
Density: 1.2850 (rough estimate)
Melting Point: 76.0 to 80.0 deg-C
Boiling Point: 140°C/3mmHg(lit.)
Flash Point: 138-140℃/3mm
Refractive Index: 1.5010 (estimate)
Solubility: Miscible with acetone.
PSA: 54.98000
LogP: 0.58640

Ethyl 1H-pyrazole-4-carboxylate Security Information

Symbol:
Prompt：warning
Signal Word：Warning
Hazard Statement： H315,H319,H335
Warning Statement： P261,P305+P351+P338
Hazardous Material transportation number：NONH for all modes of transport
WGK Germany：3
Hazard Category Code： 36/37/38
Safety Instruction： S26-S37/39
Hazardous Material Identification：
Safety Term：S26;S37/39
Risk Phrases：R36/37/38
HazardClass：IRRITANT
Storage Condition：Store at room temperature

Ethyl 1H-pyrazole-4-carboxylate Customs Data

HS CODE：2933199090
Customs Data：

China Customs Code:
2933199090

Overview:

2933199090. Other structurally non fused pyrazole ring compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Ethyl 1H-pyrazole-4-carboxylate Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Fluorochem	044041-5g	Ethyl 1H-Pyrazole-4-carboxylate	37622-90-5	98%	5g	￡15.00	2022-03-01
Fluorochem	044041-10g	Ethyl 1H-Pyrazole-4-carboxylate	37622-90-5	98%	10g	￡22.00	2022-03-01
Fluorochem	044041-25g	Ethyl 1H-Pyrazole-4-carboxylate	37622-90-5	98%	25g	￡44.00	2022-03-01
Fluorochem	044041-100g	Ethyl 1H-Pyrazole-4-carboxylate	37622-90-5	98%	100g	￡120.00	2022-03-01
AstaTech	60706-5/G	ETHYL 4-PYRAZOLECARBOXYLATE	37622-90-5	97%	5/G	$21	2022-06-01
AstaTech	60706-25/G	ETHYL 4-PYRAZOLECARBOXYLATE	37622-90-5	97%	25g	$15	2023-09-16
AstaTech	60706-100/G	ETHYL 4-PYRAZOLECARBOXYLATE	37622-90-5	97%	100g	$62	2023-09-16
abcr	AB468811-25 g	Ethyl 1H-pyrazole-4-carboxylate, min. 95%; .	37622-90-5		25g	€103.40	2023-04-21
Apollo Scientific	OR13194-5g	Ethyl 1H-pyrazole-4-carboxylate	37622-90-5	98+%	5g	￡15.00	2025-02-19
Apollo Scientific	OR13194-25g	Ethyl 1H-pyrazole-4-carboxylate	37622-90-5	98+%	25g	￡24.00	2025-02-19

Ethyl 1H-pyrazole-4-carboxylate Production Method

Production Method 1

80-11-5

623-47-2

37622-90-5

88529-79-7

5932-27-4

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Methanol , Water
1.2 Solvents: Dimethylformamide
1.3 Solvents: Diethyl ether ; 15 min, 25 °C
1.4 Reagents: Acetic acid

Reference

Laboratory-Scale Membrane Reactor for the Generation of Anhydrous Diazomethane

Dallinger, Doris; Pinho, Vagner D.; Gutmann, Bernhard; Kappe, C. Oliver, Journal of Organic Chemistry, 2016, 81(14), 5814-5823

Ethyl 1H-pyrazole-4-carboxylate Raw materials

Ethyl 1H-pyrazole-4-carboxylate Preparation Products

Ethyl 1H-pyrazole-4-carboxylate Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:37622-90-5)Ethyl 1H-pyrazole-4-carboxylate

Order Number:A6423

Stock Status:in Stock

Quantity:500g

Purity:99%

Pricing Information Last Updated:Monday, 2 September 2024 16:04

Price ($):247.0

Email:[email protected]

Product Official Link

Ethyl 1H-pyrazole-4-carboxylate Related Literature

1. Synthesis of N-substituted quaternary carbon centers through KOt-Bu-catalyzed aza-Michael addition of pyrazoles to cyclic enones

Subin Yoon,Sungbin Lee,Seung Hyun Nam,Hyejeong Lee,Yunmi Lee Org. Biomol. Chem. 2022 20 8313
2. PhIO promoted synthesis of nitrile imines and nitrile oxides within a micellar core in aqueous media: a regiocontrolled approach to synthesizing densely functionalized pyrazole and isoxazoline derivatives

Gargi Pal,Sanjay Paul,Partha Pratim Ghosh,Asish R. Das RSC Adv. 2014 4 8300
3. Silica supported palladium-phosphine as a reusable catalyst for alkoxycarbonylation and aminocarbonylation of aryl and heteroaryl iodides

Rajendra Shivaji Mane,Takehiko Sasaki,Bhalchandra Mahadeo Bhanage RSC Adv. 2015 5 94776
4. Organocatalytic electrochemical amination of benzylic C–H bonds

Zhong-Wei Hou,Laiqiang Li,Lei Wang Org. Chem. Front. 2021 8 4700
5. Organic photoredox-catalyzed oxidative azolation of unactivated fluoroarenes

Guodong Ju,Yalong Li,Yingsheng Zhao Org. Biomol. Chem. 2023 21 6503

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