Organic photoredox-catalyzed oxidative azolation of unactivated fluoroarenes?
Organic & Biomolecular Chemistry Pub Date: 2023-08-02 DOI: 10.1039/D3OB01041D
Abstract
Inexpensive and commercially available 2,4,6-triphenylpyrrolium tetrafluoroborate (TPT) is used as an organic photocatalyst for the nucleophilic aromatic substitution of unactivated fluoroarenes with pyrazole derivatives (SNAr) to form azole arenes. The use of organic photoredox catalysis enables the easy operation of this method under mild conditions. Various fluorinated aromatic compounds are suitable electrophiles for this transformation.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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