Cas no 372-39-4 (3,5-Difluoroaniline)
3,5-Difluoroaniline is a fluorinated aromatic amine with the molecular formula C?H?F?N. This compound is characterized by the presence of two fluorine atoms at the 3 and 5 positions of the aniline ring, which enhance its reactivity and stability in various chemical applications. It serves as a valuable intermediate in pharmaceutical, agrochemical, and material science industries, particularly in the synthesis of active ingredients and specialty chemicals. The fluorine substituents contribute to improved lipophilicity and metabolic stability, making it advantageous for designing bioactive molecules. Its high purity and consistent quality ensure reliable performance in synthetic processes, including cross-coupling reactions and nucleophilic substitutions.
3,5-Difluoroaniline structure
Product Name:3,5-Difluoroaniline
CAS No:372-39-4
MF:C6H5F2N
MW:129.107408285141
MDL:MFCD00007763
CID:37130
PubChem ID:96595
Update Time:2025-05-27
3,5-Difluoroaniline Chemical and Physical Properties
Names and Identifiers
-
- 3,5-Difluoroaniline
- 3,4-DIFLUOROANILINE 0.995 COLORLESS TO LIGHT YELLOW TRANSPARENT LIQUID
- 3,5-difluorobenzenamine
- 3,4-difluoro-phenylamine
- 3,5-Difluor-anilin
- 3,5-difluoro-aniline
- 3,5-DIFLUOROBENZENEAMINE
- 3,5-Difluoronitroaniline
- 3,5-Difluorophenylamine
- 5-Difluoroaniline
- Benzenamine,3,5-difluoro
- Benzenamine, 3,5-difluoro-
- KQOIBXZRCYFZSO-UHFFFAOYSA-N
- 3,5-Difluoro Aniline
- 3,5-difluoranilin
- 3,5-difluoroanilin
- 3.5-difluoroaniline
- 3,5 difluoroaniline
- PubChem2296
- 3, 5-difluoroaniline
- 3,5-Difluoro-phenylamine
- (3,5-difluorophenyl)amine
- 5AN
- KSC226A6N
- KQOIBXZRCYFZSO-UHFFFAOYSA-
- Z
- SB75374
- DB03238
- EN300-23894
- 372-39-4
- PD007310
- NSC 81289
- SCHEMBL69602
- 3,5-Difluoroaniline, purum, >=98.0% (GC)
- PS-9153
- BP-11914
- NSC-81289
- CS-D1125
- InChI=1/C6H5F2N/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2
- Q27094167
- 93F28C8C0X
- W-106555
- FT-0614587
- AC-10342
- NS00042188
- F0001-1071
- AM20061100
- Z166631028
- NSC81289
- UNII-93F28C8C0X
- A25250
- SDCCGMLS-0066233.P001
- MFCD00007763
- DTXSID0059906
- 3,5-Difluoroaniline, 98%
- D2665
- AKOS001407524
- EINECS 206-752-8
- STL169017
- DTXCID0039300
- 206-752-8
-
- MDL： MFCD00007763
- Inchi： 1S/C6H5F2N/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2
- InChI Key： KQOIBXZRCYFZSO-UHFFFAOYSA-N
- SMILES： FC1C=C(C=C(C=1)N)F
- BRN： 2802286
Computed Properties
- Exact Mass: 129.03900
- Monoisotopic Mass: 129.039006
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 9
- Rotatable Bond Count: 0
- Complexity: 87.1
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.4
- Topological Polar Surface Area: 26
Experimental Properties
- Color/Form: Not available
- Density: 1,295 g/cm3
- Melting Point: 37.0 to 41.0 deg-C
- Boiling Point: 82°C/20mmHg(lit.)
- Flash Point: Fahrenheit: 167 ° f < br / > Celsius: 75 ° C < br / >
- Refractive Index: 1,512-1,514
- PSA: 26.02000
- LogP: 2.12820
- Solubility: Not available
- Sensitiveness: Sensitive to air and light
3,5-Difluoroaniline Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Warning
- Hazard Statement： H302,H312,H332
- Warning Statement： P280
- Hazardous Material transportation number：UN 1325 4.1/PG 2
- WGK Germany：3
- Hazard Category Code： 20/21/22
- Safety Instruction： S28-S36/37/39-S26
- FLUKA BRAND F CODES：8-10-23
-
Hazardous Material Identification：
- Safety Term：6.1
- Packing Group：III
- Risk Phrases：R20/21/22; R36/37/38
- Storage Condition：Keep away from high temperature, sparks, flames and fire sources. Store in tightly closed containers. Store in a cool, dry, well ventilated area away from incompatible substances.
- Packing Group：III
- Hazard Level：6.1
- HazardClass：6.1
- PackingGroup：III
- TSCA：Yes
3,5-Difluoroaniline Customs Data
- HS CODE：2921420090
- Customs Data：
China Customs Code:
2921420090Overview:
2921420090 Other aniline derivatives and their salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
3,5-Difluoroaniline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM118179-500g |
3,5-Difluoroaniline |
372-39-4 | 95+% | 500g |
$153 | 2021-06-17 | |
| Chemenu | CM118179-1000g |
3,5-Difluoroaniline |
372-39-4 | 95+% | 1000g |
$224 | 2021-06-17 | |
| Fluorochem | 001690-5g |
3,5-Difluoroaniline |
372-39-4 | 98% | 5g |
￡12.00 | 2022-03-01 | |
| Fluorochem | 001690-25g |
3,5-Difluoroaniline |
372-39-4 | 98% | 25g |
￡20.00 | 2022-03-01 | |
| Fluorochem | 001690-100g |
3,5-Difluoroaniline |
372-39-4 | 98% | 100g |
￡34.00 | 2022-03-01 | |
| Fluorochem | 001690-250g |
3,5-Difluoroaniline |
372-39-4 | 98% | 250g |
￡70.00 | 2022-03-01 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0422029467-1g |
3,5-Difluoroaniline |
372-39-4 | 98%（GC) | 1g |
￥ 149.4 | 2024-07-20 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0422029451-5g |
3,5-Difluoroaniline |
372-39-4 | 98%（GC) | 5g |
￥ 527.1 | 2024-07-20 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0422029443-25g |
3,5-Difluoroaniline |
372-39-4 | 98%（GC) | 25g |
￥ 1294.1 | 2024-07-20 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | A808437-1g |
3,5-Difluoroaniline |
372-39-4 | 98% | 1g |
￥76.00 | 2022-09-03 |
3,5-Difluoroaniline Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:372-39-4)3,5-Difluoroaniline
Order Number:sfd5512
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:372-39-4)3,5-Difluoroaniline
Order Number:A25250
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:18
Price ($):242.0
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:372-39-4)3,5-Difluoroaniline
Order Number:LE3716
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:44
Price ($):discuss personally
Email:[email protected]
3,5-Difluoroaniline Related Literature
-
Ramana Sreenivasa Rao,Femil Joseph Shajan,D. Srinivasa Reddy Org. Biomol. Chem. 2019 17 8384
-
Jason R. Price,Yanhua Lan,Sally Brooker Dalton Trans. 2007 1807
-
Yiu-Tung Wong,Wing-Ki Law,Shirley Sau-Ling Lai,Siu-Pan Wong,Kong-Chi Lau,Clare Ho Anal. Methods 2018 10 3514
-
Zhi-Gang Niu,Jun Chen,Peng Tan,Wei Sun,You-Xuan Zheng,Gao-Nan Li,Jing-Lin Zuo Dalton Trans. 2018 47 8032
-
Yan Yin,Yuxing Sun,Lianhua Zhao,Jinpeng Pan,Yangbo Feng RSC Med. Chem. 2020 11 583
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