Cas no 37064-30-5 (Procyanidin C1)

Procyanidin C1 is a trimeric proanthocyanidin compound, classified as a condensed tannin, derived primarily from grape seeds, cocoa, and other plant sources. It exhibits strong antioxidant properties due to its ability to scavenge free radicals and chelate metal ions. Structurally, it consists of three epicatechin units linked by interflavan bonds, contributing to its stability and bioactivity. Procyanidin C1 is studied for its potential benefits in cardiovascular health, anti-inflammatory effects, and skin protection against oxidative stress. Its high molecular weight and polyphenolic nature enhance its interaction with cellular targets, making it a subject of interest in nutraceutical and pharmaceutical research.

Procyanidin C1 structure

Product Name:Procyanidin C1

CAS No:37064-30-5

MF:C₄₅H₃₈O₁₈

MW:866.772434711456

MDL:MFCD29918426

CID:309266

PubChem ID:169853

Update Time:2025-05-21

Procyanidin C1 Chemical and Physical Properties

Names and Identifiers

- [4,8':4',8''-Ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol,2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-,(2R,2'R,2''R,3R,3'R,3''R,4R,4'S)-
- [4,8':4',8''-Ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol,2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexah
- Procyanidin C1
- PROCYANIDIN C1(P) PrintBack
- (2R,3R,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
- Procyanidol C1
- Cinnamtannin A1
- Proanthocyanidin C1
- Procyanidin C-1
- Procyanidin trimer C1
- 33516LCW4F
- [Epicatechin(4b->8)]2-epicatechin
- [Epicatechin-(4beta->8)]2-epicatechin
- EC-(4b,8)-EC-(4b,8)-EC
- Epicatechin-(4beta->8)-epicatechin-(4beta->8)-epicatechin
- (2R,2'R,2''R,3R,3'R,3''R,4R,4'S)-2,2',2''-Tris(3,4-dihydroxyphenyl)-[4,8':4',8''-terchroman]-3,3',3'',5,5',5'',7,7',7''-nonaol
- (4,8':4',8''-Ter-2H-1-benzopyran)-3,3',3'
- UNII-33516LCW4F
- Proanthocyanidin C1;
- AC-35069
- 37064-30-5
- C17624
- CHEMBL290632
- PCC1
- Epicatechin-(4.beta.-->8)epicatechin-(4.beta.-->8)epicatechin
- HY-N2342
- (2R,3R,4S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-8-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
- PROCYANIDIN C1 (CONSTITUENT OF MARITIME PINE) [DSC]
- epicatechin-(4beta-8)-epicatechin-(4beta-8)-epicatechin
- EPICATECHIN-(4.BETA.->8)-EPICATECHIN-(4.BETA.->8)-EPICATECHIN
- (2R,3R,4R,2''R,3''R,4''S,2''''R,3''''R)-2,2'',2''''-Tris-(3,4-dihydroxy-phenyl)-3,4,3'',4'',3'''',4''''-hexahydro-2H,2''H,2''''H-[4,8'';4'',8'''']terchromene-3,5,7,3'',5'',7'',3'''',5'''',7''''-nonaol
- DTXCID50113053
- MS-31600
- PROCYANIDIN C1, (+)-
- AKOS027321198
- SCHEMBL678609
- Q7247556
- (2r,2'r,2''r,3r,3'r,3''r,4r,4's)-2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-2h,2'h,2''h-4,8':4',8''-terchromene-3,3',3'',5,5',5'',7,7',7''-nonol
- DTXSID10190562
- PROCYANIDIN C1 (CONSTITUENT OF MARITIME PINE)
- BDBM50240460
- (2R,3R,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-8-yl]-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-yl]chromane-3,5,7-triol
- (4,8':4',8''-Ter-2H-1-benzopyran)-3,3',3'',5,5',5'',7,7',7''-nonol, 2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-, stereoisomer
- 1ST166802
- (Epicatechin-(4beta->8))2-epicatechin
- CHEBI:75643
- (Epicatechin(4b->8))2-epicatechin
- CS-0021304
- DA-77079
- C45H38O18
- MDL： MFCD29918426
- Inchi： 1S/C45H38O18/c46-18-10-27(54)33-32(11-18)61-42(16-2-5-21(48)25(52)8-16)39(59)37(33)35-29(56)14-30(57)36-38(40(60)43(63-45(35)36)17-3-6-22(49)26(53)9-17)34-28(55)13-23(50)19-12-31(58)41(62-44(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,31,37-43,46-60H,12H2/t31-,37-,38+,39-,40-,41-,42-,43-/m1/s1
- InChI Key： MOJZMWJRUKIQGL-XILRTYJMSA-N
- SMILES： O1C2C(=C(C=C(C=2[C@H](C2=C(C=C(C3C[C@H]([C@@H](C4C=CC(=C(C=4)O)O)OC2=3)O)O)O)[C@H]([C@H]1C1C=CC(=C(C=1)O)O)O)O)O)[C@H]1C2C(=CC(=CC=2O[C@H](C2C=CC(=C(C=2)O)O)[C@@H]1O)O)O

Computed Properties

Exact Mass: 866.20600
Monoisotopic Mass: 866.20581436 g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 15
Hydrogen Bond Acceptor Count: 18
Heavy Atom Count: 63
Rotatable Bond Count: 5
Complexity: 1550
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 8
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 331
Molecular Weight: 866.8
XLogP3: 3.3

Experimental Properties

Color/Form: Brown powder
Density: 1.747±0.06 g/cm3( 20 oC : 760 Torr)
Melting Point: 140.0-142.0°C
PSA: 331.14000
LogP: 4.44390

Procyanidin C1 Security Information

Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Hazardous Material transportation number：NONH for all modes of transport
WGK Germany：3
Safety Instruction： H303+H313+H333
Storage Condition：?20°C

Procyanidin C1 Pricemore >>

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Procyanidin C1 Production Method

Procyanidin C1 Suppliers

Hubei Cuiyuan Biotechnology Co.,Ltd

Gold Member

Audited Supplier

(CAS:37064-30-5)ProcyanidinC1

Order Number:CRN0060

Stock Status:in stock

Quantity:5mg/20mg/50mg

Purity:≥98%

Pricing Information Last Updated:Friday, 14 March 2025 10:55

Price ($):

Email:[email protected]

Product Official Link

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:37064-30-5)Procyanidin C1

Order Number:LE13609

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:09

Price ($):discuss personally

Email:[email protected]

Procyanidin C1 Related Literature

1. Absorption, metabolism, distribution and faecal excretion of B-type procyanidin oligomers in mice after a single oral administration of black soybean seed coat extract

Liuqing Wang,Yoko Yamashita,Shingo Komeda,Akiko Saito,Hitoshi Ashida Food Funct. 2018 9 5362
2. Ultrahigh pressure liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry for the determination of polyphenolic profiles in the characterization and classification of cranberry-based pharmaceutical preparations and natural extracts

Lidia Parets,élida Alechaga,Oscar Nú?ez,Javier Saurina,Santiago Hernández-Cassou,Lluis Puignou Anal. Methods 2016 8 4363
3. Insights into the potential benefits of black soybean (Glycine max L.) polyphenols in lifestyle diseases

Yoko Yamashita,Hiroyuki Sakakibara,Toshiya Toda,Hitoshi Ashida Food Funct. 2020 11 7321
4. Chinese chestnut shell polyphenol extract regulates the JAK2/STAT3 pathway to alleviate high-fat diet-induced, leptin-resistant obesity in mice

Suwen Liu,Wenhong Jiang,Chang Liu,Shuo Guo,Hao Wang,Xuedong Chang Food Funct. 2023 14 4807
5. New insights on Phyllanthus reticulatus Poir. leaves and stem bark extracts: UPLC-ESI-TOF-MS profiles, and biopharmaceutical and in silico analysis

Kouadio Ibrahime Sinan,María de la Luz Cádiz-Gurrea,Francisco Javier Leyva-Jiménez,álvaro Fernández-Ochoa,Antonio Segura-Carretero,Jasmina Glamocilja,Marina Sokovic,Marija Nenadi?,Abdurrahman Aktumsek,Stefano Dall'Acqua,Gokhan Zengin New J. Chem. 2021 45 21049

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Additional information on Procyanidin C1

Procyanidin C1: A Comprehensive Overview

Procyanidin C1 (CAS No. 37064-30-5) is a bioactive compound belonging to the class of flavonoids, specifically a type of proanthocyanidin. These compounds are widely found in various plant sources, including grapes, cocoa, and certain types of tea. Procyanidin C1 has garnered significant attention in recent years due to its potential health benefits and applications in the fields of nutrition, medicine, and cosmetics.

Procyanidin C1 is structurally characterized by its unique composition, which includes two catechin units linked by a single bond. This structure contributes to its antioxidant properties, making it highly effective in neutralizing free radicals and protecting cells from oxidative damage. Recent studies have highlighted the role of Procyanidin C1 in mitigating oxidative stress, a condition linked to various chronic diseases such as cardiovascular disorders, diabetes, and neurodegenerative diseases.

The biological activity of Procyanidin C1 extends beyond its antioxidant properties. Research has demonstrated its potential anti-inflammatory effects, which could be beneficial in managing conditions like arthritis and inflammatory bowel disease. Additionally, Procyanidin C1 has shown promise in modulating cellular signaling pathways involved in cell proliferation and apoptosis, suggesting its potential role in cancer prevention and treatment.

One of the most exciting areas of research involving Procyanidin C1 is its impact on cardiovascular health. Studies have indicated that this compound may improve endothelial function, reduce blood pressure, and inhibit the oxidation of low-density lipoprotein (LDL) cholesterol—a key factor in the development of atherosclerosis. These findings underscore the potential of Procyanidin C1 as a natural supplement for promoting heart health.

Moreover, Procyanidin C1 has been explored for its cognitive benefits. Emerging evidence suggests that this compound may enhance memory and learning by improving neuronal communication and protecting against neurotoxicity. This has led to increased interest in its application as a nutraceutical for age-related cognitive decline and neurodegenerative diseases such as Alzheimer's.

The application of Procyanidin C1 extends into the cosmetic industry as well. Its potent antioxidant and anti-inflammatory properties make it a valuable ingredient in skincare products aimed at combating signs of aging, reducing inflammation, and protecting the skin from environmental stressors.

In terms of bioavailability, Procyanidin C1 is known to have relatively low absorption rates when consumed orally. However, recent advancements in delivery systems, such as encapsulation techniques and nanoformulations, have shown promise in enhancing its bioavailability and efficacy.

Despite the growing body of research on Procyanidin C1, further studies are needed to fully understand its mechanisms of action and optimal dosing strategies. Collaborative efforts between researchers, healthcare professionals, and industry experts are essential to harness the full potential of this compound for human health.

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