Cas no 133-04-0 ((-)-Asarinin)
(-)-Asarinin Chemical and Physical Properties
Names and Identifiers
-
- (-)-Asarinin
- L-Asarinin
- ASARININ
- EPI-SESAMIN
- (-)-SESAMINE
- ASARININ(RG)(SEE SESAMIN)
- 5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole)
- 5-[4-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole
- (-)-5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole]
- Asarinin, 98%, from Aristolochia debilis Sieb. & Zucc.
- 333JW641ML
- Xanthoxyln S
- Y0033
- 133A040
- 1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo(3,4-c)furan-1,4-diyl)bis-, (1R-(1alpha,3aalpha,4beta,6aalpha))-
- CHEMBL1572261
- CS-0009717
- DTXSID501033823
- s5467
- AS-76457
- pseudocubebin
- 1,3-BENZODIOXOLE, 5,5'-(TETRAHYDRO-1H,3H-FURO(3,4-C)FURAN-1,4-DIYL)BIS-, (1R-(1.ALPHA.,3A.ALPHA.,4.BETA.,6A.ALPHA.))-
- (1RS,3aRS,4SS,6aRS)-1,4-bis(benzo[d][1,3]dioxol-5-yl)hexahydrofuro[3,4-c]furan
- AKOS000278098
- UNII-333JW641ML
- Q27256222
- 5-[(3R,3aS,6S,6aS)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole
- SCHEMBL6704290
- ASARININ [MI]
- CCRIS 8100
- NCGC00142464-01
- 1,3-Benzodioxole,5,5'-[(1R,3aS,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis-
- Eleutheroside B4
- HY-N0701
- ASARININ, (-)-
- 5,5'-[(1R,3aS,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis-1,3-benzodioxole
- MFCD00198067
- 1,3-BENZODIOXOLE, 5,5'-((1R,3AS,4S,6AS)-TETRAHYDRO-1H,3H-FURO(3,4-C)FURAN-1,4-DIYL)BIS-
- CCG-268080
- AC-34863
- NCGC00017230-02
- 1ST40196
- Episesamin
- 133-04-0
- DA-59399
- (-)-Episesamin
- [1R-(1?,3a?,4?,6a?)]-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole; 1H,3H-Furo[3,4-c]furan-1,3-benzodioxole Deriv.; 5,5'-[(1R,3aS,4S,6aS)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole]; (-)-Asarinin; (-)-Episesamin;
-
- MDL： MFCD00198067
- Inchi： 1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19-,20+/m1/s1
- InChI Key： PEYUIKBAABKQKQ-FQZPYLGXSA-N
- SMILES： O1C([H])([H])[C@@]2([H])[C@@]([H])(C3C([H])=C([H])C4=C(C=3[H])OC([H])([H])O4)OC([H])([H])[C@@]2([H])[C@]1([H])C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])O2
Computed Properties
- Exact Mass: 354.11000
- Monoisotopic Mass: 354.110338
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 26
- Rotatable Bond Count: 2
- Complexity: 482
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 4
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 55.4
- Molecular Weight: 354.4
- XLogP3: 2.7
Experimental Properties
- Color/Form: Powder
- Density: 1.385
- Melting Point: 121°
- Boiling Point: 504.4 °C at 760 mmHg
- Flash Point: 212.3 °C
- Refractive Index: 1.623
- PSA: 55.38000
- LogP: 3.21920
- Specific Rotation: D20 -118.6°; D23 -122° (chloroform)
(-)-Asarinin Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：Please store the product under the recommended condition sin the description
(-)-Asarinin Customs Data
- HS CODE：2932999099
- Customs Data：
China Customs Code:
2932999099Overview:
2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
(-)-Asarinin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-N0701-5mg |
(-)-Asarinin |
133-04-0 | 99.90% | 5mg |
￥800 | 2024-04-20 | |
| MedChemExpress | HY-N0701-10mg |
(-)-Asarinin |
133-04-0 | 99.90% | 10mg |
￥1300 | 2024-04-20 | |
| MedChemExpress | HY-N0701-20mg |
(-)-Asarinin |
133-04-0 | 99.90% | 20mg |
￥1800 | 2024-04-20 | |
| S e l l e c k ZHONG GUO | S5467-1mg |
Asarinin |
133-04-0 | 99.80% | 1mg |
￥1040.63 | 2023-09-15 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A302403-50mg |
(-)-Asarinin |
133-04-0 | ≥98%(HPLC) | 50mg |
￥1799.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A302403-25mg |
(-)-Asarinin |
133-04-0 | ≥98%(HPLC) | 25mg |
￥999.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A302403-100mg |
(-)-Asarinin |
133-04-0 | ≥98%(HPLC) | 100mg |
￥3239.90 | 2023-09-04 | |
| DC Chemicals | DCX-016-20 mg |
(-)-asarinin |
133-04-0 | >98%, Standard References Grade | 20mg |
$280.0 | 2022-02-28 | |
| Chemenu | CM494013-50mg |
L-Asarinin |
133-04-0 | 97% | 50mg |
$157 | 2023-02-18 | |
| Chemenu | CM494013-100mg |
L-Asarinin |
133-04-0 | 97% | 100mg |
$538 | 2024-08-02 |
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(-)-Asarinin Related Literature
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David J. Aldous,Andrei S. Batsanov,Dmitrii S. Yufit,Anne J. Dalen?on,William M. Dutton,Patrick G. Steel Org. Biomol. Chem. 2006 4 2912
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2. Amides of vegetable origin. Part III. Structure and stereochemistry of neoHerculinL. Crombie J. Chem. Soc. 1955 995
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Can Zhao,Ijaz Khan,Yong Jian Zhang Chem. Commun. 2020 56 12431
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Lu Zheng,Xiao-Kui Huo,Chao Wang,Hai-Jian Cong,Ting Xiang,Bin Wu,Bao-Jing Zhang,Shan-Shan Huang,Lin Zhang,Xiao-Chi Ma Anal. Methods 2016 8 3359
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5. A new synthetic route to furofuranoid lignans via the intramolecular Mukaiyama reactionDavid R. Stevens,Clive P. Till,Donald A. Whiting J. Chem. Soc. Perkin Trans. 1 1992 185
Related Categories
- Solvents and Organic Chemicals Organic Compounds Lignans, neolignans and related compounds Furanoid lignans Furanoid lignans
- Solvents and Organic Chemicals Organic Compounds Lignans, neolignans and related compounds Furanoid lignans
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Reference Substances
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
Additional information on (-)-Asarinin
Exploring the Unique Properties and Applications of (-)-Asarinin (CAS No. 133-04-0)
(-)-Asarinin (CAS No. 133-04-0) is a naturally occurring lignan compound found in various plant species, particularly in the Asarum genus. This bioactive molecule has garnered significant attention in recent years due to its potential therapeutic properties and diverse applications in the pharmaceutical, nutraceutical, and cosmetic industries. Researchers and industry professionals are increasingly interested in (-)-Asarinin for its unique chemical structure and biological activities, making it a hot topic in natural product chemistry.
The chemical structure of (-)-Asarinin features a dibenzylbutyrolactone skeleton, which is characteristic of many biologically active lignans. This specific stereochemistry (the "(-)" enantiomer) is crucial for its interactions with biological targets. Recent studies have shown that (-)-Asarinin exhibits remarkable antioxidant, anti-inflammatory, and neuroprotective effects, positioning it as a promising candidate for various health applications. These properties align well with current consumer trends toward natural, plant-derived bioactive compounds.
In traditional medicine systems, plants containing (-)-Asarinin have been used for centuries to treat various ailments. Modern scientific investigations are now validating many of these traditional uses. For instance, (-)-Asarinin has demonstrated potential in supporting cardiovascular health, which is particularly relevant given the growing global focus on heart disease prevention. Its ability to modulate inflammatory pathways also makes it interesting for researchers studying chronic inflammatory conditions, a major area of interest in contemporary medicine.
The extraction and purification of (-)-Asarinin present interesting challenges for chemists and manufacturers. Advanced techniques such as preparative HPLC and chiral separation methods are often employed to obtain high-purity (-)-Asarinin for research and commercial applications. The compound's stability profile and solubility characteristics are important considerations for formulators developing products containing this bioactive ingredient.
From a market perspective, demand for (-)-Asarinin has been steadily increasing, particularly in the nutraceutical sector. Consumers are actively searching for information on "natural antioxidants", "plant-derived neuroprotective compounds", and "traditional medicine phytochemicals" - all areas where (-)-Asarinin shows promise. This aligns with the broader trend toward evidence-based herbal medicine and functional foods.
Recent research has explored the potential of (-)-Asarinin in skincare applications. Its antioxidant properties may help protect skin cells from oxidative stress, making it an interesting ingredient for anti-aging formulations. This application is particularly timely, as consumers increasingly seek out "clean beauty" ingredients with scientifically validated benefits. Cosmetic chemists are investigating optimal delivery systems for (-)-Asarinin to maximize its skin bioavailability.
Quality control is a critical aspect when working with (-)-Asarinin. Analytical methods such as HPLC-UV and LC-MS are commonly used to verify the identity and purity of (-)-Asarinin preparations. Standardization is particularly important given the compound's potential therapeutic applications, where consistent potency is essential for reproducible effects.
The biosynthesis of (-)-Asarinin in plants involves fascinating enzymatic pathways that are currently being elucidated by phytochemists. Understanding these pathways could open doors to sustainable production methods, including biotechnological approaches. This is especially relevant in the context of growing interest in "green chemistry" and sustainable sourcing of bioactive compounds.
From a regulatory standpoint, (-)-Asarinin is generally recognized as safe when derived from traditional food plants. However, as research progresses and new applications emerge, regulatory frameworks may evolve. Companies working with (-)-Asarinin should stay informed about developments in natural product regulations, particularly in different global markets.
Future research directions for (-)-Asarinin include more detailed investigations of its mechanisms of action, potential synergistic effects with other phytochemicals, and clinical validation of its health benefits. The compound's unique stereochemistry also presents interesting opportunities for structure-activity relationship studies that could lead to novel derivatives with enhanced properties.
For researchers and product developers seeking high-quality (-)-Asarinin, it's important to source material from reputable suppliers who can provide comprehensive analytical data. Key specifications to evaluate include enantiomeric purity (ensuring the "(-)" form predominates), residual solvent levels, and absence of heavy metals or other contaminants.
The growing body of scientific literature on (-)-Asarinin suggests this compound will continue to attract attention across multiple disciplines. Its combination of traditional use and modern scientific validation makes it particularly appealing in today's market where consumers value both heritage and evidence-based benefits. As research progresses, we can expect to see (-)-Asarinin incorporated into more innovative health and wellness products.
In conclusion, (-)-Asarinin (CAS No. 133-04-0) represents an intriguing example of nature's chemical diversity with significant potential for various applications. Its unique properties align well with current consumer trends and scientific interests, making it a compound worth watching in the coming years as research continues to uncover its full potential.
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