Cas no 364634-18-4 (1,2-Bis((pinacolato)boryl)ethane)

1,2-Bis((pinacolato)boryl)ethane is a versatile borylating reagent widely used in organic synthesis and cross-coupling reactions. Its key advantage lies in its stability and reactivity as a diboron compound, making it valuable for Suzuki-Miyaura couplings and other transition-metal-catalyzed transformations. The pinacolato groups enhance its air and moisture stability, facilitating handling and storage compared to more sensitive boron reagents. This compound is particularly useful for introducing boron functionalities into organic frameworks, enabling efficient C–C bond formation. Its consistent performance and compatibility with various substrates make it a reliable choice for researchers in medicinal chemistry, materials science, and catalytic applications.
1,2-Bis((pinacolato)boryl)ethane structure
364634-18-4 structure
Product Name:1,2-Bis((pinacolato)boryl)ethane
CAS No:364634-18-4
MF:C14H28B2O4
MW:281.991724967957
CID:1004713
PubChem ID:11471561
Update Time:2025-06-14

1,2-Bis((pinacolato)boryl)ethane Chemical and Physical Properties

Names and Identifiers

    • 1,2-Bis((pinacolato)boryl)ethane
    • 4,4,5,5-tetramethyl-2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl]-1,3,2-dioxaborolane
    • (pinacolato)2BCH2CH2B
    • D-1439
    • 1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane
    • 364634-18-4
    • CS-0531331
    • 2,2'-(1,2-Ethanediyl)bis[4,4,5,5-tetramethyl-1,3,2-dioxaborolane]
    • DB-422385
    • 1,3,2-Dioxaborolane, 2,2'-(1,2-ethanediyl)bis[4,4,5,5-tetramethyl-
    • 1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane; 2,2'-(1,2-Ethanediyl)bis[4,4,5,5-tetramethyl-1,3,2-Dioxaborolane
    • DTXSID10467009
    • Inchi: 1S/C14H28B2O4/c1-11(2)12(3,4)18-15(17-11)9-10-16-19-13(5,6)14(7,8)20-16/h9-10H2,1-8H3
    • InChI Key: XSJBRPOBMHZZNA-UHFFFAOYSA-N
    • SMILES: O1B(CCB2OC(C)(C)C(C)(C)O2)OC(C)(C)C1(C)C

Computed Properties

  • Exact Mass: 282.21700
  • Monoisotopic Mass: 282.2173697g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 3
  • Complexity: 311
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 36.9?2

Experimental Properties

  • PSA: 36.92000
  • LogP: 3.17080

1,2-Bis((pinacolato)boryl)ethane Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
B522740-25mg
1,2-Bis((pinacolato)boryl)ethane
364634-18-4
25mg
$ 230.00 2023-09-08
TRC
B522740-250mg
1,2-Bis((pinacolato)boryl)ethane
364634-18-4
250mg
$ 1774.00 2023-09-08
SHENG KE LU SI SHENG WU JI SHU
sc-503830-25 mg
1,2-Bis((pinacolato)boryl)ethane,
364634-18-4
25mg
¥2,858.00 2023-07-11
SHENG KE LU SI SHENG WU JI SHU
sc-503830-25mg
1,2-Bis((pinacolato)boryl)ethane,
364634-18-4
25mg
¥2858.00 2023-09-05
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1601995-25mg
1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane
364634-18-4 98%
25mg
¥3046.00 2024-05-16

1,2-Bis((pinacolato)boryl)ethane Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Sodium Solvents: Benzene
Reference
Addition Reactions of Bis(pinacolato)diborane(4) to Carbonyl Enones and Synthesis of (pinacolato)2BCH2B and (pinacolato)2BCH2CH2B by Insertion and Coupling
Ali, Hijazi Abu; Goldberg, Israel; Srebnik, Morris, Organometallics, 2001, 20(18), 3962-3965

1,2-Bis((pinacolato)boryl)ethane Raw materials

1,2-Bis((pinacolato)boryl)ethane Preparation Products

Additional information on 1,2-Bis((pinacolato)boryl)ethane

Comprehensive Overview of 1,2-Bis((pinacolato)boryl)ethane (CAS No. 364634-18-4)

1,2-Bis((pinacolato)boryl)ethane (CAS No. 364634-18-4) is a highly versatile boron-based compound widely utilized in organic synthesis, pharmaceuticals, and materials science. Its unique structure, featuring two pinacol boronate groups, makes it an essential reagent for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry. Researchers and industries value this compound for its stability, reactivity, and compatibility with diverse reaction conditions.

The growing demand for 1,2-Bis((pinacolato)boryl)ethane is driven by its applications in drug discovery and agrochemical development. With the rise of green chemistry and sustainable practices, this compound has gained attention for its role in reducing waste and improving reaction efficiency. Its ability to form carbon-boron bonds under mild conditions aligns with the industry's shift toward eco-friendly methodologies, making it a topic of frequent searches in AI-driven chemical databases and academic forums.

One of the most searched questions about CAS No. 364634-18-4 revolves around its synthetic applications. Users often inquire about its use in constructing complex biaryl structures or modifying heterocyclic compounds. Recent studies highlight its utility in OLED materials and polymeric catalysts, further expanding its relevance in cutting-edge technologies. The compound's moisture stability and handling precautions are also common discussion points, reflecting practical concerns in laboratory settings.

From an SEO perspective, keywords like "pinacol boronate synthesis," "boronic ester applications," and "364634-18-4 supplier" are frequently associated with this compound. These terms cater to both academic researchers and commercial buyers seeking high-purity reagents. The compound's role in peptide coupling and bioconjugation techniques has also sparked interest, particularly in the context of biopharmaceutical innovations.

In summary, 1,2-Bis((pinacolato)boryl)ethane (CAS No. 364634-18-4) stands as a pivotal tool in modern chemistry, bridging fundamental research and industrial applications. Its adaptability to flow chemistry and high-throughput screening underscores its future potential, ensuring continued relevance in scientific and commercial landscapes.

Recommended suppliers
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
Shanghai Bent Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.