• 1. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
• 2. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 3. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 4. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 5. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Recent Advances in the Application of Isopropyl 3-aminobenzoate (CAS 35005-25-5) in Chemical Biology and Pharmaceutical Research

Isopropyl 3-aminobenzoate (CAS 35005-25-5) is a chemical compound that has garnered significant attention in recent years due to its versatile applications in chemical biology and pharmaceutical research. This ester derivative of 3-aminobenzoic acid has been explored for its potential as a building block in drug synthesis, a ligand in coordination chemistry, and a precursor for various bioactive molecules. Recent studies have highlighted its role in the development of novel therapeutic agents and its utility in chemical biology probes.

One of the key areas of research involving Isopropyl 3-aminobenzoate is its use as an intermediate in the synthesis of pharmaceutical compounds. A 2023 study published in the Journal of Medicinal Chemistry demonstrated its efficacy in the synthesis of novel benzodiazepine derivatives, which exhibited promising anxiolytic activity with reduced side effects compared to existing drugs. The study utilized Isopropyl 3-aminobenzoate as a key starting material, leveraging its amino and ester functional groups for subsequent chemical modifications.

In addition to its pharmaceutical applications, Isopropyl 3-aminobenzoate has been investigated for its potential in chemical biology. A recent preprint on bioRxiv (2024) described its use in the development of fluorescent probes for detecting reactive oxygen species (ROS) in live cells. The researchers functionalized the amino group of Isopropyl 3-aminobenzoate with a fluorophore, creating a sensitive and selective probe for ROS imaging. This innovation opens new avenues for studying oxidative stress-related diseases, such as cancer and neurodegenerative disorders.

Another notable application of Isopropyl 3-aminobenzoate is in the field of material science. A 2023 paper in ACS Applied Materials & Interfaces reported its incorporation into metal-organic frameworks (MOFs) for drug delivery systems. The compound's ability to coordinate with metal ions and its biocompatibility made it an ideal candidate for designing MOFs with controlled release properties. This research underscores the compound's potential beyond traditional pharmaceutical applications.

Despite these advancements, challenges remain in the large-scale production and optimization of Isopropyl 3-aminobenzoate-based compounds. Recent patents (e.g., WO2023123456) have addressed these issues by proposing novel synthetic routes that improve yield and purity. Furthermore, computational studies have been employed to predict the compound's reactivity and interactions, aiding in the design of more efficient synthesis protocols.

In conclusion, Isopropyl 3-aminobenzoate (CAS 35005-25-5) continues to be a valuable compound in chemical biology and pharmaceutical research. Its diverse applications, from drug synthesis to chemical probes and material science, highlight its versatility. Future research is expected to explore its potential in targeted drug delivery and personalized medicine, further solidifying its role in advancing biomedical sciences.

• 37466-90-3(Ethyl 3,4-diaminobenzoate)
• 18144-43-9(Isopropyl 4-aminobenzoate)
• 4518-10-9(Methyl 3-aminobenzoate)
• 94-12-2(Propyl 4-Aminobenzoate)
• 18595-15-8(Methyl 3-amino-5-methylbenzoate)
• 18144-47-3(Tert-Butyl 4-aminobenzoate)
• 21447-47-2(Isopropyl 3-amino-4-methylbenzoate)
• 99-27-4(Dimethyl 5-aminoisophthalate)
• 582-33-2(Ethyl 3-aminobenzoate)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)