• 1. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 2. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
  Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
• 3. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 4. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 5. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds N-acetylarylamines
• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds N-arylamides N-acetylarylamines

N-(2-Methyl-3-Pyridinyl)-Acetamide: A Comprehensive Overview

N-(2-Methyl-3-pyridinyl)-acetamide is a chemical compound that has garnered significant attention in the field of biomedical research. This molecule belongs to the family of acetamides and features a unique pyridine ring system with specific substituents, making it a subject of interest for researchers exploring its potential applications in pharmaceuticals and biochemistry.

The structure of N-(2-Methyl-3-pyridinyl)-acetamide comprises an acetamide group attached to the nitrogen atom of a pyridine ring. The pyridine ring is substituted at positions 2 and 3 with a methyl group and hydrogen atoms, respectively. This specific substitution pattern renders the molecule distinct and imparts it with unique chemical and biological properties.

Recent studies have highlighted the potential of this compound in various biomedical applications. One of the most promising avenues is its role as a ligand in metalloprotein research. Metalloproteins are enzymes that require metal ions for their catalytic activity, and understanding their structure-function relationships is crucial for drug discovery. The ability of N-(2-Methyl-3-pyridinyl)-acetamide to coordinate with metal ions makes it a valuable tool in this context.

Another area of interest is the exploration of this compound's pharmacokinetics. Understanding how drugs are absorbed, distributed, metabolized, and excreted is essential for developing efficient therapeutic agents. Preliminary studies suggest that N-(2-Methyl-3-pyridinyl)-acetamide exhibits favorable pharmacokinetic properties, making it a potential candidate for further drug development.

In the realm of neuroscience, this compound has shown intriguing possibilities as a research tool. Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by complex molecular mechanisms, including abnormal protein aggregation. The ability of N-(2-Methyl-3-pyridinyl)-acetamide to interact with amyloid-beta peptides has been investigated, revealing its potential role in modulating these pathological processes.

Moreover, this compound has been explored for its antimicrobial properties. With the rising concern of antibiotic resistance, there is a pressing need for novel agents that can combat bacterial and fungal infections effectively. Studies have demonstrated that N-(2-Methyl-3-pyridinyl)-acetamide exhibits potent antimicrobial activity against several pathogenic strains, making it a promising lead in the development of new antimicrobial agents.

Looking ahead, the continued investigation of N-(2-Methyl-3-pyridinyl)-acetamide is expected to yield further insights into its diverse biological activities. Its unique chemical structure positions it as a versatile tool for probing fundamental biological processes and developing innovative therapeutic solutions.

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