• 1. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 2. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 3. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig

• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes Stilbenes
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes

Introduction to 4-Hydroxy-3-methoxystilbene (CAS No. 3391-75-1)

4-Hydroxy-3-methoxystilbene, identified by its Chemical Abstracts Service (CAS) number 3391-75-1, is a naturally occurring stilbenoid compound that has garnered significant attention in the field of chemobiology and pharmaceutical research. This molecule, characterized by its phenolic and methoxy substituents, exhibits a unique structural framework that contributes to its diverse biological activities. The compound belongs to the stilbene family, which is renowned for its potential health benefits, particularly in the context of antioxidant and anti-inflammatory properties.

The chemical structure of 4-Hydroxy-3-methoxystilbene consists of a central biphenyl core connected by a vinylene bridge. The presence of hydroxyl and methoxy groups at specific positions on the aromatic rings enhances its reactivity and interaction with biological targets. This structural motif is reminiscent of other well-studied stilbenes, such as resveratrol, which has been extensively researched for its role in modulating various cellular processes.

Recent advancements in molecular biology and pharmacology have highlighted the therapeutic potential of 4-Hydroxy-3-methoxystilbene. Studies have demonstrated its ability to modulate multiple signaling pathways, including those involved in oxidative stress, inflammation, and cell proliferation. These findings have positioned the compound as a promising candidate for further investigation in the development of novel therapeutic agents.

In particular, research has focused on the antioxidant properties of 4-Hydroxy-3-methoxystilbene. Oxidative stress is a critical factor in the pathogenesis of numerous diseases, including neurodegenerative disorders, cardiovascular conditions, and certain types of cancer. The compound's capacity to scavenge reactive oxygen species (ROS) and inhibit the activity of pro-oxidant enzymes has been well-documented in vitro. These effects are attributed to its phenolic structure, which allows it to participate in redox reactions and neutralize free radicals.

Moreover, 4-Hydroxy-3-methoxystilbene has shown significant anti-inflammatory activity. Chronic inflammation is another key driver of many chronic diseases, and inhibiting inflammatory pathways has emerged as a viable strategy for therapeutic intervention. Preclinical studies have indicated that this compound can suppress the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6). These findings suggest that 4-Hydroxy-3-methoxystilbene may have a role in managing inflammatory conditions.

The potential chemopreventive properties of 4-Hydroxy-3-methoxystilbene are also an area of active investigation. Cancer research has long recognized the importance of natural compounds that can modulate cellular processes associated with tumor growth and progression. Studies have suggested that 4-Hydroxy-3-methoxystilbene can induce apoptosis in certain cancer cell lines by activating stress-responsive pathways. Additionally, it has been observed to inhibit angiogenesis, the process by which new blood vessels form to supply nutrients to tumors.

From a pharmacokinetic perspective, 4-Hydroxy-3-methoxystilbene exhibits characteristics that make it an attractive candidate for therapeutic applications. Its solubility in both water and lipids allows for versatile formulation options, enhancing bioavailability. Furthermore, preliminary studies suggest that it can be metabolically active within biological systems, potentially contributing to its prolonged effects.

The synthesis and isolation of 4-Hydroxy-3-methoxystilbene have been refined through various chemical methodologies. Natural sources such as plants from the Polygonaceae family are known to contain this compound, though synthetic routes offer greater control over purity and yield. Advances in organic synthesis techniques have enabled researchers to produce high-purity samples suitable for detailed biological testing.

Future directions in research on 4-Hydroxy-3-methoxystilbene include exploring its mechanism of action in greater detail. Understanding how this compound interacts with specific biological targets will provide insights into its therapeutic potential and aid in the design of more effective derivatives. Additionally, clinical trials are needed to validate the safety and efficacy of 4-Hydroxy-3-methoxystilbene in human populations.

In conclusion,4-Hydroxy-3-methoxystilbene (CAS No. 3391-75-1) is a multifaceted compound with significant promise in the realm of chemobiology and pharmaceutical science. Its unique structural features contribute to its diverse biological activities, particularly those related to antioxidant and anti-inflammatory effects. As research continues to uncover new insights into its mechanisms and applications,4-Hydroxy-3-methoxystilbene may emerge as a valuable component in future therapeutic strategies.

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