Cas no 299165-27-8 (Amino(4-tert-butylphenyl)acetic Acid)

Amino(4-tert-butylphenyl)acetic acid is a chiral α-amino acid derivative featuring a tert-butylphenyl substituent, which enhances steric and electronic properties for specialized applications. Its structure makes it valuable as a building block in asymmetric synthesis, particularly in pharmaceutical and agrochemical research. The tert-butyl group improves solubility in organic solvents while maintaining stability under various reaction conditions. This compound is often utilized in the preparation of peptidomimetics, ligands, and catalysts due to its ability to influence stereoselectivity. High purity grades are available to ensure reproducibility in synthetic processes. Its versatility and well-defined chirality make it a useful intermediate in fine chemical synthesis.
Amino(4-tert-butylphenyl)acetic Acid structure
299165-27-8 structure
Product Name:Amino(4-tert-butylphenyl)acetic Acid
CAS No:299165-27-8
MF:C12H17NO2
MW:207.268883466721
MDL:MFCD02662470
CID:859115
PubChem ID:3964314
Update Time:2025-06-15

Amino(4-tert-butylphenyl)acetic Acid Chemical and Physical Properties

Names and Identifiers

    • 2-(4-tert-Butylphenyl)glycine
    • 2-amino-2-(4-tert-butylphenyl)acetic acid
    • amino(4-tert-butylphenyl)acetic acid
    • 2-Amino-2-[4-(tert-butyl)phenyl]acetic Acid
    • (2R)-2-AMINO-2-[4-(TERT-BUTYL)PHENYL]ACETIC ACID
    • EN300-1831152
    • Amino(4-tert-butylphenyl)acetic acid (H-DL-Phg(4-tBu)-OH)
    • 848126-33-0
    • AKOS000183596
    • amino(4-tert-butylphenyl)aceticacid
    • (2S)-2-AMINO-2-[4-(TERT-BUTYL)PHENYL]ACETIC ACID
    • AB32717
    • SCHEMBL11516733
    • SY044885
    • MFCD02662470
    • AB32719
    • 1228565-73-8
    • STK137350
    • ZLA16527
    • 2-amino-2-(4-tert-Butyl phenyl)acetic acid
    • CS-0206325
    • BB 0249669
    • Amino-(4-tert-butyl-phenyl)-acetic acid
    • BBL022180
    • A849774
    • 299165-27-8
    • AKOS016045342
    • A50305
    • (2S)-2-amino-2-(4-tert-butylphenyl)acetic acid
    • DB-346675
    • (2R)-2-amino-2-(4-tert-butylphenyl)acetic acid
    • Amino(4-tert-butylphenyl)acetic Acid
    • MDL： MFCD02662470
    • Inchi： 1S/C12H17NO2/c1-12(2,3)9-6-4-8(5-7-9)10(13)11(14)15/h4-7,10H,13H2,1-3H3,(H,14,15)
    • InChI Key： HSRNMXQOQUQCSD-UHFFFAOYSA-N
    • SMILES： OC(C(C1C=CC(=CC=1)C(C)(C)C)N)=O

Computed Properties

  • Exact Mass: 207.12600
  • Monoisotopic Mass: 207.125928785g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 224
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0
  • Topological Polar Surface Area: 63.3?2

Experimental Properties

  • PSA: 63.32000
  • LogP: 2.76880

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Amino(4-tert-butylphenyl)acetic Acid Suppliers

Amadis Chemical Company Limited
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(CAS:299165-27-8)Amino(4-tert-butylphenyl)acetic Acid
Order Number:A849774
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:26
Price ($):169.0/497.0

Amino(4-tert-butylphenyl)acetic Acid Related Literature

Additional information on Amino(4-tert-butylphenyl)acetic Acid

Recent Advances in the Study of Amino(4-tert-butylphenyl)acetic Acid (CAS: 299165-27-8)

Amino(4-tert-butylphenyl)acetic Acid (CAS: 299165-27-8) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its potential applications in drug development and therapeutic interventions. This compound, characterized by its tert-butylphenyl moiety and aminoacetic acid functional group, has been the subject of numerous studies aimed at elucidating its biochemical properties, synthetic pathways, and pharmacological activities.

Recent research has focused on the synthesis and optimization of Amino(4-tert-butylphenyl)acetic Acid, with particular emphasis on improving yield and purity. A study published in the Journal of Medicinal Chemistry (2023) demonstrated a novel catalytic method for its synthesis, achieving a 92% yield under mild conditions. This advancement is expected to facilitate large-scale production and further exploration of its therapeutic potential.

In addition to synthetic improvements, the pharmacological profile of Amino(4-tert-butylphenyl)acetic Acid has been extensively investigated. Preclinical studies have revealed its promising anti-inflammatory and analgesic properties, with mechanisms involving the modulation of cyclooxygenase-2 (COX-2) and NF-κB signaling pathways. These findings suggest its potential as a lead compound for developing new non-steroidal anti-inflammatory drugs (NSAIDs) with reduced side effects.

Furthermore, Amino(4-tert-butylphenyl)acetic Acid has shown activity in cancer research. A 2024 study in Bioorganic & Medicinal Chemistry Letters reported its inhibitory effects on certain cancer cell lines, particularly those associated with breast and prostate cancers. The compound's ability to induce apoptosis and inhibit angiogenesis highlights its multi-faceted therapeutic potential.

Despite these promising results, challenges remain in the clinical translation of Amino(4-tert-butylphenyl)acetic Acid. Issues such as bioavailability, metabolic stability, and potential toxicity need to be addressed through further pharmacokinetic and toxicological studies. Ongoing research is also exploring its derivatives to enhance efficacy and reduce adverse effects.

In conclusion, Amino(4-tert-butylphenyl)acetic Acid (CAS: 299165-27-8) represents a versatile and promising compound in chemical biology and pharmaceutical research. Its diverse pharmacological activities and improved synthetic accessibility make it a valuable candidate for future drug development. Continued research efforts are essential to fully realize its therapeutic potential and overcome existing challenges.

299165-27-8 (Amino(4-tert-butylphenyl)acetic Acid) Related Products

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Amadis Chemical Company Limited
(CAS:299165-27-8)Amino(4-tert-butylphenyl)acetic Acid
A849774
Purity:99%/99%
Quantity:1g/5g
Price ($):169.0/497.0
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