Production Method 1

56-81-5

298-12-4

56-82-6

144-62-7

473-81-4

79-14-1

Reaction Conditions

1.1R:KOH, C:Cu, S:H2O, 4 h

Reference

A versatile single-copper-atom electrocatalyst for biomass valorization

By Zhou, Yongfang et al, Applied Catalysis, 2023, 324, 122218

2-oxoacetic acid Raw materials

• Glycerol

2-oxoacetic acid Preparation Products

• DL-Glyceraldehyde (56-82-6)
• Oxalic acid (144-62-7)
• 2,3-Dihydroxypropanoic Acid(20% in water) (473-81-4)
• 2-hydroxyacetic acid (79-14-1)
• 2-oxoacetic acid (298-12-4)

• 1. Self-catalytic mechanism of prebiotic reactions: from formamide to pterins and guanine
  Venelin Enchev,Sofia Slavova Phys. Chem. Chem. Phys. 2021 23 19043
• 2. Selective nickel-catalyzed dehydrogenative–decarboxylative formylation of indoles with glyoxylic acid
  Zhiping Yin,Zechao Wang,Xiao-Feng Wu Org. Biomol. Chem. 2018 16 3707
• 3. 920. Olefinic acids. Part VIII. α-Bromocyclohexylideneacetic acid
  D. D. E. Newman,L. N. Owen J. Chem. Soc. 1952 4713
• 4. Thallimetric Oxidations. Part III. Determination of glyoxylic acid and binary mixtures of glyoxylic, oxalic and formic acids by photochemical methods
  S. R. Sagi,K. Appa Rao,M. S. Prasada Rao Analyst 1984 109 53
• 5. Radical 5-exo cyclization of alkynoates with 2-oxoacetic acids for synthesis of 3-acylcoumarins
  Tong Liu,Qiuping Ding,Qianshou Zong,Guanyinsheng Qiu Org. Chem. Front. 2015 2 670

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acids

2-oxoacetic Acid (CAS No. 298-12-4): A Comprehensive Overview

2-oxoacetic acid (CAS No. 298-12-4), also known as glyoxylic acid, is a versatile organic compound that plays a significant role in various chemical and biological processes. This compound is characterized by its unique structure, which includes a carboxylic acid group and a ketone group, making it a valuable intermediate in the synthesis of numerous pharmaceuticals, agrochemicals, and fine chemicals.

The chemical formula of 2-oxoacetic acid is C₂H₂O₃, and it has a molecular weight of approximately 74.03 g/mol. The compound is a colorless liquid at room temperature and is highly soluble in water. Its reactivity and functional groups make it an essential building block in organic synthesis, particularly in the formation of esters, amides, and other derivatives.

In the realm of pharmaceutical research, 2-oxoacetic acid has garnered significant attention due to its potential applications in drug development. Recent studies have explored its role as a precursor in the synthesis of antiviral agents, anticancer drugs, and other therapeutic compounds. For instance, a study published in the Journal of Medicinal Chemistry highlighted the use of 2-oxoacetic acid in the synthesis of novel antiviral agents targeting RNA viruses, demonstrating its potential in combating viral infections.

Beyond pharmaceuticals, 2-oxoacetic acid is also utilized in the agrochemical industry. It serves as an intermediate in the production of herbicides and pesticides, contributing to the development of more effective and environmentally friendly agricultural products. Research published in the Pest Management Science journal discussed the synthesis of new herbicides using 2-oxoacetic acid, emphasizing its role in enhancing crop protection while minimizing environmental impact.

In the field of fine chemicals, 2-oxoacetic acid is employed in the production of various specialty chemicals, including fragrances, dyes, and polymers. Its unique chemical properties make it an ideal candidate for these applications, where precise control over molecular structure is crucial. A recent study in the Journal of Polymer Science explored the use of 2-oxoacetic acid in the synthesis of biodegradable polymers, highlighting its potential for sustainable materials science.

The environmental impact of 2-oxoacetic acid has also been a subject of interest. Researchers have investigated its biodegradability and toxicity to ensure its safe use in industrial processes. A study published in the Environmental Science & Technology journal reported that 2-oxoacetic acid exhibits good biodegradability under aerobic conditions and has low toxicity to aquatic organisms, making it a more environmentally friendly alternative to other organic acids.

In conclusion, 2-oxoacetic acid (CAS No. 298-12-4) is a multifunctional compound with wide-ranging applications across various industries. Its unique chemical structure and reactivity make it an indispensable intermediate in pharmaceuticals, agrochemicals, and fine chemicals. Ongoing research continues to uncover new possibilities for its use, further solidifying its importance in modern chemistry and biology.

• 286367-59-7(Ethanedioic-13C2 acid,dihydrate (9CI))
• 6153-56-6(Oxalic acid dihydrate)
• 2706-75-4(Acetic acid, oxo-,sodium salt (9CI))
• 1047-25-2(Ferrous oxalate dihydrate)
• 127609-92-1(Protein (mouse geneHox-1.4 reduced) (9CI))
• 6047-25-2(Iron(II) Oxalate Dihydrate)
• 15321-61-6(Ferrioxalate)
• 28877-87-4(Ethanedioic acid,neodymium(3+) salt, hydrate (3:2:?))
• 2065-73-8(Oxalic Acid-d2)
• 19469-07-9(Iron, [m-[ethanedioato(2-)-kO1,kO2':kO1',kO2]]bis[ethanedioato(2-)-kO1,kO2]di-, hydrate (9CI))